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Ophthalmology General

Development of VFDs after PPV

Oct 15, 2020

Pars plana vitrectomy (PPV) is a commonly done procedure in patients with idiopathic epiretinal membrane (iERM) so that their vision can get better. Postoperative visual field defects (VFDs) were repo...

Internal carotid and vertebral artery dissections - a comparison of clinical, radiological and prognostic characteristics.

Oct 15, 2020

To examine whether baseline characteristics, potential risk factors, clinical symptoms, radiological presentation, and long-term outcomes differ between internal carotid artery dissection (ICAD) and v...

Inducing differentiation of human dental pulp cells toward acinar-lineage.

Oct 15, 2020

To induce acinar-differentiation from human dental pulp cells for potential application in aiding treatment of dry-eye syndromes.Human dental pulp cells were co-cultured with human submandibular gland...

Immunohistological study of palpebral lobe of the lacrimal gland in severe dry eyes secondary to Stevens-Johnson syndrome.

Oct 15, 2020

To detect the immunohistochemical changes in the main lacrimal glands of patients suffering from chronic ocular sequelae of Stevens-Johnson syndrome (SJS).Histological sections of biopsies from the la...

Corneal Nerve abnormalities in ocular and systemic diseases.

Oct 15, 2020

The trigeminal nerve gives rise to the corneal subbasal nerve system, which plays a crucial role in sensations of touch, pain, and temperature and in ocular healing processes. Technological advancemen...

Metformin attenuated histopathological ocular deteriorations in a streptozotocin-induced hyperglycemic rat model.

Oct 15, 2020

Diabetes mellitus (DM) often causes ocular disorders leading to vision loss. Metformin is commonly prescribed for type 2 diabetes. This study assessed the effect of metformin on hyperglycemic histopat...

NETosis contributes to the pathogenesis of diabetes and its complications.

Oct 15, 2020

NETosis, a novel form of neutrophil-related cell death, acts as a major regulator of diabetes and diabetes-associated complications. In this review, we show that the extrusion of neutrophil extracellu...

The influence of hyperglycaemia on the safety of ultrasound in retinal pigment epithelial cells.

Oct 15, 2020

Ultrasound (US) assisted drug delivery is receiving interest in treating posterior eye diseases such as diabetic retinopathy (DR) due to its ability to maximise drug penetration into difficult to reac...

Gypenosides attenuate retinal degeneration in a zebrafish retinitis pigmentosa model.

Oct 15, 2020

Retinitis pigmentosa (RP) is a collection of heterogenous genetic retinal disorders resulting in cumulative retinal deterioration involving progressive loss of photoreceptors and eventually in total b...

Canaloplasty and Trabeculotomy with the OMNI System in Pseudophakic Patients with Open-Angle Glaucoma: the ROMEO Study.

Oct 15, 2020

Provide outcomes up to 12 months post-surgically for sequential canaloplasty and trabeculotomy with the OMNI surgical system (OMNI) in pseudophakic patients with mild to moderate open-angle glaucoma (...

Functional impact of a congenital stationary night blindness type 2 mutation depends on subunit composition of Ca1.4 Ca channels.

Oct 12, 2020

Voltage-gated Ca1 and Ca2 Ca channels are comprised of a pore-forming a1 subunit (Ca1.1-1.4, Ca2.1-2.3) and auxiliary β (β) and αδ (αδ-1-4) subunits. The properties of these channels vary with d...

Therapeutic potential of castor oil in managing blepharitis, meibomian gland dysfunction and dry eye.

Oct 12, 2020

The multifactorial pathogenesis and interrelationship of blepharitis, meibomian gland dysfunction and dry eye disease poses challenges to any therapeutic approach. Current treatments are mostly pallia...

Validation of a Novel Confocal Microscopy Imaging Protocol With Assessment of Reproducibility and Comparison of Nerve Metrics in Dry Eye Disease Compared With Controls.

Oct 12, 2020

The purposes of this study were to assess the reproducibility of a novel standardized technique for capturing corneal subbasal nerve plexus images with in vivo corneal confocal microscopy and to compa...

The cornea in keratoconjunctivitis sicca.

Oct 12, 2020

The lacrimal functional unit (LFU) regulates tear production, composition, distribution and clearance to maintain a stable protective tear layer that is essential for maintaining corneal epithelial he...

Lactoferrin Concentration in Human Tears and Ocular Diseases: A Meta-Analysis.

Oct 12, 2020

To evaluate the potential of lactoferrin (Lf) as a diagnostic biomarker for ocular diseases using a meta-analytic approach.All original studies reporting an estimate of the average Lf concentration in...

Optical coherence tomography angiography findings in patients undergoing transcorneal electrical stimulation for treating retinitis pigmentosa.

Oct 12, 2020

Transcorneal electrical stimulation (TES) is a novel treatment approach for patients with retinitis pigmentosa (RP). The aim of our study was to observe changes in optical coherence tomography angiogr...

Changes in intraocular pressure control in the first year after secondary intraocular lens implantation in children.

Oct 12, 2020

To compare intraocular pressure (IOP) control before and during the first year after secondary intraocular lens (IOL) implantation in children.This was a retrospective chart review of children who rec...

Limbal stem cell deficiency secondary to systemic paclitaxel (Taxol) for breast cancer: a case report.

Oct 12, 2020

Paclitaxel (PTX) is an antineoplastic drug widely used in treatments for ovarian, breast, and small-cell lung cancer. Although ocular effects associated with PTX have been previously described, very f...

Deep learning in glaucoma with optical coherence tomography: a review.

Oct 12, 2020

Deep learning (DL), a subset of artificial intelligence (AI) based on deep neural networks, has made significant breakthroughs in medical imaging, particularly for image classification and pattern rec...

Blood Biomarkers and 6- to 7-Year Childhood Outcomes Following Neonatal Encephalopathy.

Oct 12, 2020

 This study aimed to profile the cytokine/chemokine response from day 0 to 7 in infants (≥36 weeks of gestational age) with neonatal encephalopathy (NE) and to explore the association with long-te...