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Ophthalmology General

Evaluating the Effect of a Myopia Control Spectacle Lens Among Children in Israel: 12-Month Results.

Sep 11, 2023

To investigate the effectiveness of a novel spectacle lens designed to slow the progression of myopia in children.A prospective, randomized, double blind clinical trial.126 Israeli children aged 6-13 ...

Evaluating the Efficacy of Polyglycolic Acid-Loading Tetrandrine Nanoparticles in the Treatment of Dry Eye.

Sep 11, 2023

Dry eye disease (DED) is a multifactor-induced disease accompanied by increased osmolarity of the tear film and inflammation of the ocular surface. Traditional anti-inflammation agent corticosteroids ...

Choroidal Structural Changes in Patients with Early Diabetic Nephropathy.

Sep 11, 2023

To determine alterations of the choroidal thickness (CT) and the choroidal vascularity index (CVI) in patients with glomerular hyperfiltration, a marker of early diabetic nephropathy (DN).Twenty-two p...

Molecular Regulatory Mechanism of Human Myosin-7a.

Sep 11, 2023

Myosin-7a is an actin-based motor protein essential for vision and hearing. Mutations of myosin-7a cause Usher syndrome type 1, the most common and severe form of deaf-blindness in humans. The molecul...

Insulin-like growth factor binding protein-3 mediates hyperosmolar stress-induced mitophagy through the mechanistic target of rapamycin.

Sep 11, 2023

Hyperosmolarity of the ocular surface triggers inflammation and pathological damage in dry eye disease (DED). In addition to a reduction in quality of life, DED causes vision loss and when severe, bli...

Heads-Up Three-Dimensional Viewing Systems in Vitreoretinal Surgery: An Updated Perspective.

Sep 11, 2023

Three-Dimensional (3D) heads-up visualization systems have significantly advanced vitreoretinal surgery, providing enhanced detail and improved ergonomics. This review discusses the application of 3D ...

Punctate Inner Pachychoroidopathy. Demographic and Clinical Features of Inner Choroidal Inflammation in Eyes with Pachychoroid Disease.

Sep 04, 2023

To perform an unsupervised machine learning clustering of patients with punctate inner choroidopathy (PIC) and provide new insights into the significance of pachychoroid disease features in PIC eyes.R...

Correlation of the macular microvasculature to the axial length in pediatric patients with high axial refractive errors.

Sep 04, 2023

To compare the vascular density (VD) of the macular superficial capillary plexus (SCP), deep capillary plexus (DCP), and choriocapillaris (CC), and the foveal avascular zone (FAZ) among high hyperopic...

Culture of primary human meibomian gland cells from surgically excised eyelid tissue.

Sep 04, 2023

Meibomian gland dysfunction is one of the most common ocular diseases, with therapeutic treatment being primarily palliative due to our incomplete understanding of meibomian gland (MG) pathophysiology...

TFOS lifestyle report executive summary: A lifestyle epidemic - Ocular surface disease.

Sep 04, 2023

The Tear Film & Ocular Surface Society (TFOS) Workshop entitled 'A Lifestyle Epidemic: Ocular Surface Disease' was a global initiative undertaken to establish the direct and indirect impacts of ev...

Deploying efficient net batch normalizations (BNs) for grading diabetic retinopathy severity levels from fundus images.

Sep 04, 2023

Diabetic retinopathy (DR) is one of the main causes of blindness in people around the world. Early diagnosis and treatment of DR can be accomplished by organizing large regular screening programs. Sti...

A Real-world Dataset and Benchmark For Foundation Model Adaptation in Medical Image Classification.

Sep 04, 2023

Foundation models, often pre-trained with large-scale data, have achieved paramount success in jump-starting various vision and language applications. Recent advances further enable adapting foundatio...

Effects of pictorial warning labels depicting lesser-known and well-known risks of smoking on viewing patterns, recall, and knowledge of smoking harms.

Sep 04, 2023

In 2019, the Food and Drug Administration introduced 11 pictorial warning labels (PWLs) for inclusion on cigarette packages, created in compliance with court recommendations and tailored to increase k...

Use of Mitomycin C in Dacryocystorhinostomy: A Report by the American Academy of Ophthalmology.

Sep 04, 2023

To review the literature on the adjuvant use of mitomycin C (MMC) during dacryocystorhinostomy (DCR) in adults with primary nasolacrimal duct obstructions (NLDOs) to determine the efficacy in improvin...

Therapeutic Potential of Cannabinoids in Glaucoma.

Aug 28, 2023

Glaucoma is a leading cause of irreversible blindness worldwide. To date, intraocular pressure (IOP) is the only modifiable risk factor in glaucoma treatment, but even in treated patients, the disease...

Effects of blue light exposure on ocular parameters and choroidal blood perfusion in Guinea pig.

Aug 28, 2023

To investigate the impact of different duration of blue light exposure on ocular parameters and choroidal blood perfusion in guinea pigs with lens-induced myopia.Three-week-old Guinea pigs were random...

Efficacy of different powers of Low-level Red Light in Children Myopia Control.

Aug 28, 2023

This study aimed to compare the efficacy and safety of low-intensity red light (LRL) in controlling myopia progression across three different powers (0.37 mW, 0.60 mW, and 1.20 mW).Single-center, sing...

TNF is a critical cytokine in age-related dry eye disease.

Aug 28, 2023

Aging is a complex biological process that is characterized by low-grade inflammation, called inflammaging. Aging affects multiple organs including eye and lacrimal gland. Tumor necrosis factor (TNF) ...

Limbal Stem Cell Dysfunction Induced by Severe Dry Eye via Activation of the p38 MAPK Signaling Pathway.

Aug 28, 2023

Severe dry eye (SDE) can cause grievous damage of the ocular surface and result in vision impairment and even blindness. To investigate the fate of limbal stem cells in SDE and the underlying mechanis...

The effect of Central and peripheral thyroid resistance indices on diabetic retinopathy: a study of hospitalized euthyroid patients with T2DM in China.

Aug 28, 2023

This study aims to explore the correlation between central and peripheral thyroid resistance indices and diabetic retinopathy(DR) in patients with type 2 diabetes mellitus (T2DM), so as to provide a c...

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