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Ophthalmology General

Reversible corneal stromal thinning, acute-onset white cataract and angle-closure glaucoma due to erdafitinib, a fibroblast growth factor receptor inhibitor: Report of three cases.

Nov 12, 2020

To report corneal and lens toxicity in patients undergoing chemotherapy with erdafitinib, a fibroblast growth factor receptor (FGFR) inhibitor.This retrospective case series contains three patients fr...

MicroRNA expression profile of Lacrimal Glands in rabbit autoimmune dacryoadenitis model.

Nov 12, 2020

To identify the differential expression of microRNAs (miRs) and the related gene networks and signal pathways in lacrimal glands (LGs) of rabbit autoimmune dacryoadenitis. Autoimmune dacryoadenitis ...

Effect of 808-nm Laser Photobiomodulation Treatment in Blepharitis Rat Model.

Nov 12, 2020

Blepharitis, simply defined as eyelid inflammation, is one of the common ocular conditions associated with discomfort and irritation. Because blepharitis causes meibomian gland dysfunction and dry eye...

Investigation of macular and optic nerve head structural changes using spectral domain optical coherence tomography in internal carotid artery stenosis.

Nov 12, 2020

To demonstrate differences in optic nerve head (ONH), retinal nerve fiber layer (RNFL), and macular thickness in patients with internal carotid artery (ICA) stenosis using spectral domain optical cohe...

Identification of microvascular and morphological alterations in eyes with central retinal non-perfusion.

Nov 12, 2020

To evaluate the characteristics and morphological alterations in central retinal ischemia caused by diabetic retinopathy (DR) or retinal vein occlusion (RVO) as seen in optical coherence tomography an...

Using retinal function to define ischemic exclusion criteria for animal models of glaucoma.

Nov 12, 2020

Most animal models of glaucoma rely on induction of ocular hypertension (OHT), yet such models can suffer from high IOPs leading to undesirable retinal ischemia. Thus, animals with IOPs exceeding a th...

The Minimal Clinically Important Difference in Glaucoma Medication Adherence: Interviews of Glaucoma Experts.

Nov 12, 2020

Poor adherence to glaucoma medications is associated with progressive vision loss. While many interventions have sought to increase glaucoma medication adherence, the amount by which adherence must in...

Inter-Eye Comparison of Focal Lamina Cribrosa Defect in Normal Tension Glaucoma Patients with Asymmetric Visual Field Loss.

Nov 12, 2020

To evaluate the association of focal lamina cribrosa (LC) defect with asymmetric visual field (VF) loss in normal tension glaucoma (NTG) through inter-eye comparisons.Paired eyes were divided into bet...

What are Ophthalmology Patients Asking Online? An Analysis of the Eye Triage Subreddit.

Nov 12, 2020

Ophthalmology patients are seeking medical advice on social media websites like Reddit, where users are able to post comments and discuss issues pertaining to different topics that are organized in 's...

Ophthalmic Technology Assessment Interventions for Indirect Traumatic Optic Neuropathy A report by the American Academy of Ophthalmology.

Nov 12, 2020

To review the literature on the efficacy and safety of medical and surgical interventions for indirect traumatic optic neuropathy (TON), defined as injury to the nerve that occurs distal to the optic ...

Ophthalmic immune-related adverse events following anti-CTLA-4 or PD-1 therapy recorded in the American Academy of Ophthalmology IRIS® Registry.

Nov 12, 2020

Detailed study of ophthalmic immune-related adverse events (OirAEs), including determination of incidence and recurrence rates, is of integral importance in the evolving field of cancer immunotherapy ...

[Ocular manifestations of viral diseases].

Nov 12, 2020

Viral infections may involve all ocular tissues and may have short and long-term sight-threatening consequences. Among them, ocular infections caused by herpesviruses are the most frequent. HSV-1 kera...

Disparities in Outpatient Ophthalmologic Care

Nov 11, 2020

Research indicates discrepancies in access to healthcare and prevalence of ophthalmologic conditions based on demographic characteristics, with the prevalence of primary ophthalmologic diseases differ...

3-D assessment of gaze-induced eye shape deformations and downgaze-induced vitreous chamber volume increase in highly myopic eyes with staphyloma

Nov 09, 2020

The study was done to determine if the stress of normal eye movements results in gaze-induced globe deformations, vitreous chamber axial length and vitreous chamber axial volume (VCAV) change in highl...

Keratoconus staging by decades

Nov 09, 2020

This study aims to analyse the keratoconus (KC) stage distribution at different ages within the Homburg Keratoconus Center (HKC). 1000 patients were selected out of which 728 of the patients were mal...

Automated detection of early-stage ROP using a deep convolutional neural network

Nov 09, 2020

The study was done to automatically detect and classify the early stages of retinopathy of prematurity (ROP) using a deep convolutional neural network (CNN). This retrospective cross-sectional study ...

Ophthalmic adverse effects of immune checkpoint inhibitors: the Mayo Clinic experience

Nov 09, 2020

This study was done to investigate immune-related ophthalmic side effects of systemic checkpoint inhibitors and compare side effect frequency and requirement for cessation of immunotherapy by checkpoi...

Standardisation of optical coherence tomography angiography nomenclature in uveitis: first survey results

Nov 09, 2020

The study was done to standardise the nomenclature for reporting OCT-A findings in the field of uveitis. Members of the International Uveitis Study Group, of the American Uveitis Society and of the S...

The association of clinical phenotypes to known AD/FTD genetic risk loci and their inter-relationship.

Nov 09, 2020

To elucidate how variants in genetic risk loci previously implicated in Alzheimer's Disease (AD) and/or frontotemporal dementia (FTD) contribute to expression of disease phenotypes, a phenome-wide ass...

PPARγ modulates refractive development and form deprivation myopia in Guinea pigs.

Nov 09, 2020

Form deprivation myopia (FDM) is characterized by loss of choroidal thickness (ChT), reduced choroidal blood perfusion (ChBP), and consequently scleral hypoxia. In some tissues, changes in levels of p...