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Ophthalmology General

Effects of congenital ptosis on the refractive development of eye and vision in children.

Nov 23, 2020

To investigate the influence of unilateral congenital ptosis on the development of the eye and vision in children.In this prospective observational study, 41 patients with unilateral congenital ptosis...

Myopia progression varies with age and severity of myopia.

Nov 23, 2020

To investigate annual myopia progression in individuals from South Indian states across different age groups, and its association with age of onset and severity of myopia.This retrospective study incl...

Consistency between optical coherence tomography and humphrey visual field for evaluating glaucomatous defects in high myopic eyes.

Nov 23, 2020

The study is to investigate the influence of high myopia on the consistency between optical coherence tomography (OCT) and visual field in primary open-angle glaucoma (POAG).We enrolled 37 patients wi...

A randomised clinical trial of multifocal contact lenses and contact lens discomfort.

Nov 23, 2020

To determine how multifocal contact lenses affect contact lens discomfort.This randomised, participant-masked, crossover clinical trial fitted 84 uncomfortable soft contact lens wearers (30-40 years ...

Esculetin protects human corneal epithelial cells from oxidative stress through Nrf-2 signaling pathway.

Nov 23, 2020

Dry eye formation often originates from oxidative damage to the ocular surface, which can be caused by external environment or internal pathologic factors. Esculetin (6, 7-dihydroxycoumarin) is a natu...

End of Study Results for the Ladder Phase 2 Trial of the Port Delivery System with Ranibizumab for Neovascular Age-Related Macular Degeneration.

Nov 23, 2020

To report the end of study results from the Ladder clinical trial of the Port Delivery System with ranibizumab (PDS) for the treatment of neovascular age-related macular degeneration (nAMD).Multicente...

Serum essential trace elements and toxic metals in Chinese diabetic retinopathy patients.

Nov 23, 2020

Trace elements are essential for the proper functioning of proteins, enzymes, and transcriptional factors. However, toxic metals will compete with essential trace elements, and damage enzymatic activi...

The SUSTech-SYSU dataset for automated exudate detection and diabetic retinopathy grading.

Nov 23, 2020

Automated detection of exudates from fundus images plays an important role in diabetic retinopathy (DR) screening and evaluation, for which supervised or semi-supervised learning methods are typically...

Prevalence and associated factors of glaucoma in the Russian Ural Eye and Medical Study.

Nov 23, 2020

To assess the prevalence and associated factors of glaucoma in a Russian population. The population-based Ural Eye and Medical Study included 5899 (mean age 59.0 ± 10.7 years; range 40-94 years...

Treat-and-extend versus fixed bimonthly treatment regimens for treatment-naive neovascular age-related macular degeneration: real world data from the Fight Retinal Blindness registry.

Nov 23, 2020

To compare the outcomes of two different antivascular endothelial growth factor treatment regimens for treatment-naive eyes with neovascular age-related macular degeneration in routine clinical care a...

Organoids and organ chips in ophthalmology.

Nov 23, 2020

Recent advances have driven the development of stem cell-derived, self-organizing, three-dimensional miniature organs, termed organoids, which mimic different eye tissues including the retina, cornea,...

What are Ophthalmology Patients Asking Online? An Analysis of the Eye Triage Subreddit.

Nov 20, 2020

Ophthalmology patients are seeking medical advice on social media websites like Reddit, where users are able to post comments and discuss issues pertaining to different topics that are organized in 's...

What can anisometropia tell us about eye growth?

Nov 20, 2020

The study explored the interocular differences in biometry to determine the potential role of other factors in refractive development. In 362 subjects Childhood Errors of Refraction study were studie...

Rapid assessment of avoidable blindness-based healthcare costs of diabetic retinopathy in Hungary and its projection for the year 2045

Nov 20, 2020

The purpose of this study was to estimate the total healthcare cost associated with DR in the population aged 18 years and older in Hungary, and its projection for the year 2045. A cost model was dev...

Ultra-wide-field scanning laser ophthalmoscopy and optical coherence tomography in FEVR: findings and its diagnostic ability

Nov 20, 2020

The study was done to describe some novel vitreoretinal microstructural findings in patients with mild FEVR on UWF-SLO and UWF optical coherence tomography (UWF-OCT) and to evaluate their clinical sig...

Outcomes of gonioscopy-assisted transluminal trabeculotomy in pseudoexfoliative glaucoma: 24-month follow-up

Nov 20, 2020

The study was done to report on outcomes of gonioscopy-assisted transluminal trabeculotomy (GATT) in eyes with PXG. 103 eyes from 84 patients with PXG were enrolled to undergo a 360-degree ab interno...

National approaches to trichiasis surgical follow-up, outcome assessment and surgeon audit in trachoma-endemic countries in Africa

Nov 20, 2020

The study was done to assess national approaches to trichiasis surgical follow-up, outcome assessment and audit, and identify national targets for good surgical outcome. A cross-sectional survey was ...

Genetic associations of myopia severities and endophenotypes in children

Nov 20, 2020

The study was done to investigate the associations of multiple SNPs with the severities and endophenotypes of myopia in children. 3300 children aged were recruited. 13 SNPs in 13 genes/loci were sele...

The Cologne rebubbling study: a reappraisal of 624 rebubblings after Descemet membrane endothelial keratoplasty

Nov 20, 2020

The study was done to analyse graft detachments prior to rebubbling, the influence of rebubbling on the postoperative outcome after Descemet membrane endothelial keratoplasty (DMEK) and the need for r...

Anaesthesia for ophthalmic procedures in patients with thyroid eye disease.

Nov 19, 2020

Thyroid eye disease is an autoimmune inflammatory disorder of the orbit in adults. It causes inflammation, expansion and fibrosis of orbital fat, muscles and the lacrimal gland, leading to facial disf...