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Ophthalmology General

Discovery of Spilanthol Endoperoxide as a Redox Natural Compound Active against Mammalian Prx3 and Infection.

Dec 10, 2020

(Ct) is a bacterial intracellular pathogen responsible for a plethora of diseases ranging from blindness to pelvic inflammatory diseases and cervical cancer. Although this disease is effectively trea...

The lived experiences of work and health of people living with deaf-blindness due to Usher syndrome type 2.

Dec 10, 2020

: This study aimed to explore lived experiences with working life from the perspective of people with deafblindness due to Usher syndrome type 2 (USH2). : A limited number of studies have explored wor...

Efficacy and safety of atropine to control myopia progression: a systematic review and meta-analysis.

Dec 10, 2020

The effect and safety of atropine on delaying the progression of myopia has been extensively studied, but its optimal dose is still unclear. Therefore, the purpose of this meta-analysis is to systemat...

Exploring non-adherence to contact lens wear schedule: Subjective assessments and patient related factors in children wearing single vision and myopia control contact lenses.

Dec 10, 2020

To determine factors associated with non-adherence to contact lens wear schedule involving single vision and myopia control contact lenses in children.Data from 379 children enrolled in a prospective,...

Smartphone Overuse and Visual Impairment in Children and Young Adults: Systematic Review and Meta-Analysis.

Dec 10, 2020

Smartphone overuse has been cited as a potentially modifiable risk factor that can result in visual impairment. However, reported associations between smartphone overuse and visual impairment have bee...

Effect of Long-Term Topical Antiglaucoma Medication Use on the Ocular Surface.

Dec 10, 2020

The purpose of this study was to describe the prevalence and pattern of ocular surface disease (OSD) in glaucoma patients using preserved topical antiglaucoma medications in a Nigerian population.A co...

Efficacy and Safety of Sodium Hyaluronate/chondroitin Sulfate Preservative-free Ophthalmic Solution in the Treatment of Dry Eye: A Clinical Trial.

Dec 10, 2020

: To evaluate the efficacy of a preservative free sodium hyaluronate/chondroitin sulfate ophthalmic solution (SH/CS-PF) in patients with dry eye disease (DED). : This was a randomized phase IV, multic...

Ocular Discomfort and Quality of Life Among Patients in the Dry Eye Assessment and Management Study.

Dec 10, 2020

To assess the association of severity of ocular discomfort with measures of quality of life among patients with moderate to severe dry eye disease (DED).This is a prospective, observational, cohort st...

Machine Learning Based Automated Segmentation and Hybrid Feature Analysis for Diabetic Retinopathy Classification Using Fundus Image.

Dec 10, 2020

The object of this study was to demonstrate the ability of machine learning (ML) methods for the segmentation and classification of diabetic retinopathy (DR). Two-dimensional (2D) retinal fundus (RF) ...

Patient Perspectives of Diabetes and Diabetic Retinopathy Services in Kiribati: A Qualitative Study.

Dec 10, 2020

Diabetes mellitus is an increasing global health problem affecting millions of people worldwide, especially true in the Republic of Kiribati, with >20% of adults suffering from type 2 diabetes, and...

Robust and Interpretable Convolutional Neural Networks to Detect Glaucoma in Optical Coherence Tomography Images.

Dec 10, 2020

Recent studies suggest that deep learning systems can now achieve performance on par with medical experts in diagnosis of disease. A prime example is in the field of ophthalmology, where convolutional...

A wearable contact lens sensor for noninvasive in-situ monitoring of intraocular pressure.

Dec 10, 2020

Glaucoma is the second leading cause of blindness in the world. Intraocular pressure (IOP) is a primary indicator of glaucoma which can be measured for the treatment of the disease. This paper present...

Effect of Sensitivity Disparity Between the Two Eyes on Pointwise Monocular Sensitivity Under Binocular Viewing in Patients With Glaucoma.

Dec 10, 2020

PRéCIS:: A difference between monocular sensitivities measured with and without occlusion was observed in glaucoma. Monocular sensitivity without occlusion could have been affected differently by bin...

Choroidal alterations of Sturge-Weber syndrome secondary glaucoma and non-glaucoma port-wine stain patients distinguished by enhanced depth imaging optical coherence tomography.

Dec 10, 2020

To evaluate the choroidal changes in Sturge-Weber syndrome (SWS) secondary glaucoma and non-glaucoma port-wine stain (PWS) patients by enhanced depth imaging optical coherence tomography (EDI-OCT).SWS...

Calculating the economic burden of presumed microbial keratitis admissions at a tertiary referral centre in the UK.

Dec 10, 2020

Microbial keratitis (MK) is the most common non-surgical ophthalmic emergency admission in the UK. However, few prospective health-economic studies of MK have been performed, and no specific healthcar...

Microsporidial stromal keratitis: characterization of clinical features, and ultrastructural study by electron microscopy and efficacy of different surgical modalities

Dec 10, 2020

Researchers conducted this study to report the clinical manifestations, ultrastructure, and evaluate the efficacy of therapeutic lamellar keratectomy (TLK) and penetrating keratoplasty (PK) for micros...

Three-year follow-up of accelerated transepithelial corneal cross-linking for progressive paediatric keratoconus

Dec 08, 2020

Researchers did this study to investigate the long-term safety and efficacy of accelerated transepithelial corneal cross-linking (ATE-CXL) in children with progressive keratoconus. Fifty-three eyes o...

Long-term visual outcomes of the Boston type I keratoprosthesis in Canada

Dec 08, 2020

Researchers did this study to evaluate Boston type I keratoprosthesis (KPro) surgery’s long-term visual outcomes and identify risk factors for visual failure. The present study was a single surgeon...

Visual and refractive outcomes and complications in femtosecond laser-assisted versus conventional phacoemulsification cataract surgery: findings from a randomized, controlled clinical trial

Dec 08, 2020

Researchers conducted this study to compare visual and refractive outcomes, changes in IOP, and complications of FLACS to CPS in paired eyes from the same patients. This secondary analysis included 1...

Effectiveness of an innovative and comprehensive eye care model for individuals in residential care facilities: results of the residential ocular care (ROC) multicentred randomized controlled trial

Dec 08, 2020

The researchers did this study to assess the clinical and patient-centered effectiveness of a novel residential ocular care model in Australian individuals residing in residential care. The ROC arm c...