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Ophthalmology General

Prevalence of myopic macular degeneration worldwide

Dec 22, 2020

Researchers did this study to investigate the prevalence of MMD in the global population. Researchers selected only those published literature of population-based studies on MMD prevalence with preci...

Optical coherence tomography-based consensus definition for lamellar macular hole

Dec 22, 2020

A consensus on a definition of LMH and similar conditions is needed. The panel reviewed relevant peer-reviewed literature to reach an accord on LMH definition and differentiate LMH from similar situat...

Prediction of OCT images of short-term response to anti-VEGF treatment

Dec 22, 2020

Researchers did this study to generate and evaluate individualized post-therapeutic optical coherence tomography (OCT) images that could predict the short-term response of antivascular endothelial gro...

Improved localization and discrimination of heat-emitting household objects

Dec 22, 2020

Researchers did this study to demonstrate the potential clinically meaningful benefits of a thermal camera integrated with the Argus II, an artificial vision therapy system. Seven blind patients impl...

Asymmetry analysis of macular optical coherence tomography angiography

Dec 22, 2020

Quantitative analysis of OCT-A images requires a reproducible approach that accounts for sectoral loss. This study’s objective was to determine whether an index that accounts for both global (perfus...

Discriminating glaucomatous and compressive optic neuropathy

Dec 22, 2020

Researchers did this study to assess a deep learning classifier’s performance for GON differentiation from CON based on ganglion cell–inner plexiform layer (GCIPL) and RNFL spectral-domain optical...

Prevalence and determinants of uncorrected refractive error among a socially vulnerable older adult population living in Armenia.

Dec 21, 2020

This study estimated the prevalence of uncorrected refractive error (URE) and its determinants in a socially vulnerable older population living in Armenia.The study design used in the stidy is a cross...

Application of WES Towards Molecular Investigation of Congenital Cataracts: Identification of Novel Alleles and Genes in a Hospital-Based Cohort of South India.

Dec 21, 2020

Congenital cataracts are the prime cause for irreversible blindness in children. The global incidence of congenital cataract is 2.2-13.6 per 10,000 births, with the highest prevalence in Asia. Nearly ...

Wavefront excimer laser refractive surgery for adults with refractive errors.

Dec 21, 2020

Refractive errors (conditions in which the eye fails to focus objects accurately on the retina due to defects in the refractive system), are the most common cause of visual impairment. Myopia, hyperop...

Incidence and Outcomes of Suprachoroidal Hemorrhage Following Aurolab Aqueous Drainage Implant in Adult and Pediatric Glaucoma.

Dec 21, 2020

Postoperative suprachoroidal hemorrhage is an infrequent but devastating complication after non-valved aqueous drainage implant surgery and demonstrated a bimodal distribution. The final outcomes of e...

Intravitreal Anti-Vascular Endothelial Growth Factor Injection versus Laser Photocoagulation for Retinopathy of Prematurity: A Meta-Analysis of 3701 Eyes.

Dec 21, 2020

We investigate the efficacy and safety of intravitreal injection (IVI) of anti-vascular endothelial growth factor agents and laser photocoagulation (LPC) for retinopathy of prematurity (ROP). We perfo...

Assessment of patient burden from dry eye disease using a combination of five visual analogue scales and a radar graph: a pilot study of the PENTASCORE.

Dec 21, 2020

Dry eye disease (DED) questionnaires would ideally be easy and fast to answer and explore the main aspects of disease burden and satisfaction (efficacy and tolerability) with treatment. This pilot stu...

An Association Rule Analysis of Combined Acupoints for the Treatment of Patients with Dry Eye Disease.

Dec 21, 2020

Dry eye disease (DED) has a higher incidence in old age and is seen predominantly in females worldwide. Neurosensory abnormalities, ocular surface inflammation and damage, film instability, and hypero...

Dry Eye Disease Association with Computer Exposure Time Among Subjects with Computer Vision Syndrome.

Dec 21, 2020

To assess the time of exposure to the computer and dry eye disease (DED) in subjects with computer vision syndrome (CVS).A cross-sectional study was conducted in office workers, computer users of both...

Interphotoreceptor Retinol-Binding Protein Ameliorates Diabetes-induced Retinal Dysfunction and Neurodegeneration through Rhodopsin.

Dec 21, 2020

Diabetic patients often experience visual defects before any retinal pathologies are detected. The molecular mechanism for the visual defects in early diabetes has not been elucidated. Our previous st...

Human plasminogen-derived N-acetyl-Arg-Leu-Tyr-Glu antagonizes VEGFR-2 to prevent blood-retinal barrier breakdown in diabetic mice.

Dec 21, 2020

Targeting the vascular endothelial growth factor (VEGF)/its receptor-2 (VEGFR-2) system has become a mainstay of treatment for many human diseases, including retinal diseases. We examined the therapeu...

Protective effects of the novel amine-oxidase inhibitor multi-target drug SZV 1287 on streptozotocin-induced beta cell damage and diabetic complications in rats.

Dec 21, 2020

Diabetes mellitus is a common metabolic disease leading to hyperglycemia due to insufficient pancreatic insulin production or effect. Amine oxidase copper containing 3 (AOC3) is an enzyme that belongs...

Common aspects between glaucoma and brain neurodegeneration.

Dec 21, 2020

Neurodegeneration can be defined as progressive cell damage to nervous system cells, and more specifically to neurons, which involves morphologic alterations and progressive loss of function until cel...

A Service Coverage Analysis of Primary Congenital Glaucoma Care Across the United States.

Dec 21, 2020

To assess the number of infants at risk of delayed primary congenital glaucoma (PCG) evaluation due to long travel times to specialists.Cross-sectional geospatial service coverage analysis.All America...

Dominant optic atrophy: Culprit mitochondria in the optic nerve.

Dec 21, 2020

Dominant optic atrophy (DOA) is an inherited mitochondrial disease leading to specific degeneration of retinal ganglion cells (RGCs), thus compromising transmission of visual information from the reti...