Tislelizumab for advanced esophageal squamous cell carcinoma
1. Median overall survival was 17.2 months in the tislelizumab group versus 10.6 months in the...
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Oncology
Previously treated advanced endometrial cancer treated with lenvatinib plus pembrolizumab results in greater survival than chemotherapy alone
1. Overall survival is longer for patients receiving a combination of lenvatinib plus...
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Spirituality may influence the aggressiveness of end-of-life treatments in cancer patients
1. In this scoping review, spiritual care offered by the medical team typically led to more...
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Prostate cancer overscreening persists despite guideline changes
1. This retrospective cohort study demonstrated that males over the age of 70 are overscreened for...
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Narrow margin excision of T1a melanoma not associated with recurrence or melanoma-specific mortality
1. Wide local excision of T1a melanoma near critical structures with narrow (5-mm) margins was not...
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Cardiac magnetic resonance tissue biomarkers unlikely to identify cancer therapy-related cardiac dysfunction in patients with breast cancer
1. Cardiac magnetic resonance (CMR) imaging demonstrated myocardial inflammation and edema in...
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CAR-T Cell Therapy for Relapsed or Refractory High-Risk Neuroblastoma
1. GD2-CART01 infusion had an overall response of 63% of patients (33% complete response) with a...
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Belzutifan plus cabozantinib for immunotherapy pre-treated advanced renal cell carcinoma
1.The objective response rate was 30.8% with the majority attributing to partial response. 2. Most...
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Physical activity may improve disease-free survival following resection of stage III colon cancer
1. In this cohort study, physical activity was associated with improved disease-free survival in...
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Programmed death-ligand 1 copy number alterations may provide an additional predictive measure for response to immunotherapy in non-small cell lung cancer
1. Programmed death-ligand 1 copy number loss was identified as an independent risk factor for the...
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Preexisting heart failure associated with lower use of anthracyclines and chemotherapy
1. In this longitudinal cohort study of 30 728 patients with diffuse large-B-cell lymphoma,...
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Reminiscence therapy improves mental health outcomes in cancer survivors
1. In this systematic review and meta-analysis, cancer survivors who received reminiscence therapy...
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Disulfiram is not effective as an adjunctive therapy to standard chemotherapy for glioblastoma
1. Adding disulfiram and copper to standard alkylating chemotherapy for glioblastoma (GB) was not...
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Helicobacter pylori, Homologous Recombination Genes, and Risk of Gastric Cancer
1. The following genes had statistically significant increased odds ratio of gastric cancer;...
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Hyperfractionated radiotherapy reduces complication rates compared to standard fractionation for locally advanced nasopharyngeal carcinoma
1. Fewer patients in the hyperfractionation group reported grade 3 or worse late radiation-induced...
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United States patients receive subcutaneous fluids less frequently than intravenous fluids when compared to Canadian patients
1. Canadian patients receive subcutaneous administration of medications and/or fluids more...
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Alternative Dose Regimens of Exemestane in Postmenopausal Women with Breast Cancer
1. Through the reduction in serum estradiol, there was noninferiority between the 3-times-weekly...
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Adenoma detection rate is inversely associated with post-colonoscopy colorectal cancer risk
1. In this prospective cohort study, the adenoma detection rate (ADR) was inversely associated...
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Nivolumab plus ipilimumab does not improve survival in post-nephrectomy patients with renal cell carcinoma
1. Disease-free survival in the placebo group was 50.7 months and was never reached in the...
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Active monitoring, prostatectomy, and radiotherapy as treatment options for localized prostate cancer result in similar prostate-cancer-mortality
1. Localized prostate cancer mortality remains similar between groups receiving prostatectomy,...
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