Gene Expression Profiles Predict Benefit From Neoadjuvant Immune Checkpoint Therapy in Triple-Negative Breast Cancer
The GeparNuevo trial sheds light on the role of RNA expression from peripheral immune cells in...
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Oncology
Olanzapine as an adjunct to standard antiemtic therapy for patients receiving chemotherapy
Bookmark1. The addition of olanzapine to standard antiemetic therapy had a significantly higher...
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Zolbetuximab improves survival in patients with advanced or metastatic gastric adenocarcinoma
Bookmark1. Median progression-free survival in zolbetuximab group was greater than in the placebo...
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Surgical removal of tonsils and adenoids may slightly increase risk of cancer development
Bookmark1. Surgical removal of the tonsils and adenoids was associated with slightly increased...
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Characterization of cancer development risk following pediatric radiation exposure from computed tomography
BookmarkEvidence rating level: 3 (Average) 1. Exposure to a higher cumulative number of pediatric...
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Quizartinib improves overall median survival in patients with acute myeloid leukemia
Bookmark1. Overall survival in the quizartinib group was 31.9 months compared to 15.1 months in...
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WB: Chemoimmunotherapy Not Linked With Overall Benefit Vs. Immunotherapy Alone
Chemoimmunotherapy was linked with no survival advantage versus immunotherapy alone in advanced...
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High body mass index associated with increased risk of gastrointestinal cancers
Bookmark1. Individuals with an overweight or obese body mass index (BMI) are at increased risk for...
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Tumour stroma ratio predicts prognosis and PD-L1 expression in hepatocellular carcinoma
Bookmark1. The tumour stroma ratio (TSR) is a prognostic biomarker for predicting recurrence-free...
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Temporary interruption of endocrine therapy in women with endocrine-responsive breast cancer did not affect cancer outcomes
Bookmark1. The 3-year incidence of breast cancer in the study group was 8.9% compared to 9.2% in...
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Trifluridine–Tipiracil and Bevacizumab Improves Survival in Metastatic Pretreated Colorectal Cancer
Bookmark1. The median overall survival was 10.8 months in the combination group (FTD–TPI +...
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Venetoclax in addition to ibrutinib effective as a treatment for chronic lymphocytic leukemia
Bookmark1. High genetic risk participants with chronic lymphocytic leukemia (CLL) taking...
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DVD and telephone-based interventions effective to increase rates of cancer screening in rural areas
Bookmark1. For female patients living in rural areas, an interactive DVD intervention and...
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Measuring the rate of change of breast density over time may help to refine breast cancer screening
Bookmark1. A significantly slower rate of breast density decline over time was observed in the...
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Adagrasib in Advanced Solid Tumors Harboring a KRASG12C Mutation
Bookmark1. The overall objective response rate was 35.1% in patients with initial measurable...
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Cesarean delivery may be associated with increase odds of developing early-onset colorectal cancer in women
Bookmark1. In a case-control study based in Sweden, females born by C-section had greater odds of...
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‘Inform and Empower’ Patients on PrEP to Start HPV Vaccine Series
Incorporating HPV vaccination into PrEP services may increase the number of patients who receive...
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Stereotactic radiosurgery did not outperform conventional external beam radiotherapy in patients with localized vertebral metastatic lesions
1. Pain response at 3 months post-treatment show no advantage of stereotactic radiosurgery vs....
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Long-Term Outcomes of Sotorasib in KRAS-G12C Non–Small-Cell Lung Cancer
1. Sotorasib showed prolonged efficacy with a median OS of 12.5 months (33% at 24 months) and an...
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Gastrointestinal cancer patients may have low spiritual well-being
1. In this cross-sectional study, the mean score for spiritual well-being among patients with...
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