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Ovarian Cancer

Cancer antigen 125 expression enhances the gemcitabine/cisplatin-resistant tumor microenvironment in bladder cancer.

Jan 02, 2023

Cancer antigen 125 (CA125) is one of the mucin family proteins and is a serum tumor marker for various tumors, such as ovarian cancer, endometrial cancer, pancreatic cancer, and bladder cancer, used t...

The prognosis predictive score around primary debulking surgery (PPSP) improves diagnostic efficacy in predicting the prognosis of ovarian cancer.

Jan 02, 2023

In recent years, the pretreatment inflammatory responses have proven to predict the prognosis, but no report exists analyzing the combined inflammatory response of the pre- and postsurgical treatment....

Integrated multi-omic analysis of low-grade ovarian serous carcinoma collected from short and long-term survivors.

Dec 19, 2022

Low-grade serous ovarian cancer (LGSOC) is a rare disease that occurs more frequently in younger women than those with high-grade disease. The current treatment is suboptimal and a better understandin...

Pretreatment Nutritional Status in Combination with Inflammation Affects Chemotherapy Interruption in Women with Ovarian, Fallopian Tube, and Peritoneal Cancer.

Dec 12, 2022

Discontinuing chemotherapy worsens cancer prognosis. This study aimed to investigate the relationship between nutritional status at the start of chemotherapy and chemotherapy discontinuation in patien...

Fertility Options for Patients With Gynecological Cancer

Nov 04, 2022

For patients with early-stage endometrial cancer (EC), standard treatment has been hysterectomy with bilateral salpingo-oophorectomy with lymphadenectomy, note the authors of a study published in ...

Immune Microenvironment Manipulation for Uterine Cancer

Oct 04, 2022

Studies show that endometrial cancer (EC) rates are increasing in younger people with obesity is a likely contributor to this observed proliferation because it raises estrogen production and adipokine...

Conservative Vs Surgical Management of Atypical Endometrial Hyperplasia

Oct 04, 2022

Endometrial hyperplasia (EH), a known risk factor for endometrial cancer (EC), is an irregular proliferation of the adrenal glands increasing the gland to stroma ratio. If it manifests as atypical end...

Foreseeing Uterine Cancer’s Lymph Node Metastasis (LNM)

Oct 01, 2022

Histopathological criteria have a huge role in the preoperative categorization in endometrial carcinoma (EC). Due to the danger of lymph node metastasis (LNM), the diagnostic performance is moderate. ...

Feasibility of Adjuvant Radiation Therapy to Treat Gynecological Cancer

Oct 01, 2022

Endometrial cancer is a widely recognized female threat. It usually affects around 40,000 women every year. Numerous prospective arbitrary trials have been published. However, despite that, there stil...

MetS Tied to Poor Prognosis in Some Uterine Cancers

Sep 19, 2022

Metabolic syndrome was tied closely to poor prognosis among patients with endometrial cancer, according to a study published in Frontiers in Endocrinology. For the retrospective study—conducted at a...

Patients Undergoing Gynecologic Cancer Surgery Face Insurance-Based Disparities and Financial Toxicity

Sep 14, 2022

For a study, researchers sought to assess the association between insurance status and clinical and financial outcomes and financial toxicity (FT) risk among inpatients receiving gynecologic cancer re...

Financial Toxicity in Gynecologic Cancers: Patient-Reported Drivers

Sep 12, 2022

For a study, researchers sought to comprehend the effects that treatment-related financial burden has on gynecologic cancer patients and to pinpoint areas that may be targeted for treatments to lessen...

Uterine Carcinosarcoma: Combined Chemotherapy & EBRT

Sep 12, 2022

With stage, I to IV uterine carcinosarcoma patients are treated with surgery followed by adjuvant chemotherapy alone, radiation therapy alone, or a combination of chemotherapy and radiation therapy. F...

Financial Toxicity Has ‘Profound Impact’ in Gynecologic Oncology

Jun 13, 2022

Patients undergoing surgery for gynecologic cancer, particularly those without insurance, experience a significant risk for financial toxicity, according to findings published in Gynecologic Oncology....

Pyroptosis-Related Genes May Have a Prominent Role in Uterine Cancer

Jun 07, 2022

The linguistic origin of pyroptosis is Greek—pyro meaning fire and ptosis meaning falling or dropped. In science, the term pyroptosis appropriately refers to a highly inflammatory pathway toward reg...

Molecular Classification Can Indicate Survival in Gynecologic Cancer Recurrence

Apr 28, 2022

Molecular classification served as a significant marker of survival following endometrial cancer (EC) recurrence, with patterns of recurrence that varied based on molecular subgroups, according to fin...

Microbiome Differs in Black Vs White Women With Gynecologic Cancer

Apr 27, 2022

Black women experience higher mortality from endometrial cancer (EC) than White women, according to published data, and potential reasons for this disparity include increased rates of obesity and more...

How tamoxifen (sometimes) induces uterine cancer: affecting the PI3K pathway

Dec 15, 2021

Long-term use of tamoxifen is associated with an increased risk for the development of uterine cancer. New research shows that tamoxifen directly activates a signaling pathway (PIK3) that is a well-kn...

Updated results from RxPONDER confirm importance of menopausal status on treatment efficacy

Dec 14, 2021

The phase 3 RxPONDER trial evaluated the benefit of adjuvant chemotherapy followed by endocrine therapy in women with HR-positive, HER2-negative, early-stage breast cancer and 1–3 positive nodes. Up...

Unmet Needs for Gynecologic Malignancy

Dec 14, 2021

There remains an “urgent need” for better therapies, as well as earlier diagnosis and earlier identification of recurrences, in endometrial cancer, according to the authors of a study published in...

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