Ovarian Cancer
Sep 17, 2020
Platinum resistant ovarian cancer, usually defined as progression occurring within 6 months after completing platinum-based therapy, is a heterogeneous disease with poor prognosis and short survival (...
Sep 14, 2020
Ovarian cancer is one of the most common gynecological cancers with high morbidity and mortality, which seriously endangers women's health and quality of life. Long noncoding RNAs (lncRNAs) can regula...
Sep 14, 2020
Vitamin D has been intensively studied for its association with human health, but the scope of such association and the causal role of vitamin D remain controversial. We aim to comprehensively investi...
Sep 14, 2020
We investigated N-hydroxy l-Arginine (NOHA) predictive response in serous ovarian carcinoma based on estrogen-hormone receptor expression status; and assessed the distinctive NOHA response between est...
Sep 10, 2020
The chemotherapy response score (CRS) proposed by Bohm and colleagues in 2015 has been validated as a reproducible method for determining histopathologic response of tubo-ovarian carcinoma to neoadjuv...
Sep 10, 2020
A number of studies have reported aberrant glycosylation in connection with malignancy. Our investigation further expands on this topic through the examination of N-glycans, which could be associated ...
Sep 10, 2020
About 70% of ovarian cancer (OvCa) cases are diagnosed at advanced stages (stage III/IV) with only 20-40% of them survive over 5 years after diagnosis. A reliably screening marker could enable a par...
Sep 07, 2020
To assess clinical and psychosocial outcomes of nurse-led follow-up in survivorship care of gynaecological malignancies.Women with endometrial or ovarian cancer who were attending regular post-treatme...
Sep 07, 2020
Ovarian cancer is the leading cause of death among gynecologic cancer patients. Although platinum-based chemotherapy as a frontline treatment for ovarian cancer has been widely used in clinical settin...
Sep 07, 2020
This study aims to develop an immune-related genes (IRGs) prognostic signature to stratify the epithelial ovarian cancer (EOC) patients. We identified 332 up- and 154 down-regulated EOC-specific IRGs....
Sep 03, 2020
Ovarian cancer is the most lethal diseases among women. The chemo-resistance has been a big challenge for the cancer treatment. It has been reported that metformin may inhibit ovarian cancer and is ab...
Sep 03, 2020
N6-methyladenosine (m6A) RNA methylation, one of the common RNA modifications, has been determined to execute crucial functions on tumorigenesis and cancer development. The m6A "writers" including Met...
Sep 03, 2020
Platinum is the backbone of systemic treatment in ovarian cancer and development of platinum resistance is associated with poor survival. Here, we perform a comprehensive review of the literature rega...
Aug 31, 2020
Ovarian cancer (OVCA) is characterized by genomic/molecular intra-patient heterogeneity (IPH). Tissue histology and morphological features are surrogates of the underlying genomic/molecular contexture...
Aug 31, 2020
The majority of ovarian cancer (OC) patients recur with a platinum-resistant disease. OC cells activate adaptive resistance mechanisms that are only partially described. Here we show that OC cells can...
Aug 31, 2020
To compare reproductive and oncologic outcomes of patients diagnosed with early stage epithelial ovarian carcinoma, borderline ovarian tumors, or non-epithelial ovarian carcinoma according to receipt ...
Aug 27, 2020
Interval cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) showed promising oncologic outcomes for patients with advanced ovarian cancer, but a large-scale, multice...
Aug 27, 2020
Contradicting results regarding ovarian cancer prognosis in women with endometriosis have been reported in the literature. Due to the small sample size of previous studies, larger studies are required...
Aug 27, 2020
The objective of this study was to evaluate the status of MYC and PVT1, which are frequently amplified in malignant tumors, and to assess their biological features according to histological subtypes i...
Aug 24, 2020
Ovarian cancer is the leading cause of cancer-related death among women. Complete cytoreductive surgery followed by platinum-taxene chemotherapy has been the gold standard for a long time. Various com...