Mar 18, 2021

Questionnaires designed to score the severity of faecal incontinence (FI) are widely used to provide an evaluation of symptoms across settings, studies and time. The Pelvic Floor Disorders Consortium ...

Mar 18, 2021

Rectovaginal fistula (RVF) after low anterior resection for rectal cancer is troublesome and refractory. Although various surgical procedures have been previously described, no definitive procedure ha...

Mar 18, 2021

Depression and anxiety occur frequently postpartum, calling for early detection and treatment. Evidence on risk factors may support early detection, but is inconclusive. Our aim was to identify risk f...

Mar 18, 2021

Poly (ADP-ribose) polymerase (PARP) inhibitors are being developed in maintenance and recurrence treatment settings of epithelial ovarian cancers (EOCs) with BRCA 1-2 genes mutation. PARP inhibitors a...

Mar 18, 2021

Hereditary breast and ovarian cancer (HBOC) is primarily associated with mutations in the BRCA1/2 genes. However, causal variants in other high, moderate, and low penetrance genes proportionally incre...

Mar 18, 2021

To determine the accuracy of interpretation of a non-contrast MRI protocol in characterizing adnexal masses.Two hundred ninety-one patients (350 adnexal masses) who underwent gynecological MRI at our ...

Mar 18, 2021

This review aimed to evaluate the current evidence on the effectiveness and safety of fennel (Foeniculum vulgare Miller) for managing menopausal women's health. Fourteen databases were searched. We in...

Mar 18, 2021

Endometriosis is an inflammation-dependent disease which shares similarities with malignant tumors including attachment and infiltration. Tripartite motif containing 24 (TRIM24) has been illustrated i...

Mar 18, 2021

The ongoing COVID-19 global pandemic is a stressful experience that is particularly likely to negatively affect cancer patients. The goal of this qualitative study was to explore how breast cancer pat...

Mar 18, 2021

Asian American women, both immigrant and US-born, are known to have low mammography screening rates. To reduce health disparities and address community health needs, we undertook a systematic review t...

Mar 15, 2021

Urinary tract infection (UTI) by antibiotic-resistant strains has become increasingly problematic, with trends that differ from country to country. This study examined cross-resistance and the mechani...

Mar 15, 2021

Limited evidence about the presence of Acanthamoeba spp. in urine specimens collected from urinary catheters of the patients in the intensive care units persuaded our study. No evidence has been found...

Mar 15, 2021

Knowledge of the fundamental properties of the urinary bladder is required to better understand its pathological conditions. Research on the passive and active properties of the bladder during stretch...

Mar 15, 2021

To determine the trajectories of platelet counts and the prevalence of gestational thrombocytopenia (<150 × 10/L) during normal pregnancies and pregnancies with complications, such as hypertensi...

Mar 15, 2021

The objective of this study was to evaluate the effects of gestational exposure to low doses of bisphenol A (BPA), bisphenol S (BPS), and bisphenol F (BPF) on pregnancy outcomes and offspring developm...

Mar 15, 2021

Targeting cell division by chemotherapy is a highly effective strategy to treat a wide range of cancers. However, there are limitations of many standard-of-care chemotherapies: undesirable drug toxici...

Mar 15, 2021

Y box binding protein 1 (YB-1) is a multifunctional protein associated with tumor progression and the emergence of treatment resistance (TR). Here, we report an azopodophyllotoxin small molecule, SU05...

Mar 15, 2021

Clinical studies suggest altered systemic vascular biology in cancer patients. We assessed expression patterns of endothelial activation- and vascular leakage-related genes in tumor as well as in tumo...

Mar 15, 2021

To identify the contribution of mutations in the Desert Hedgehog (DHH) gene to the disorders of sexual differentiation (DSD) and male infertility.The study included a total 430 subjects, including 47 ...

Mar 15, 2021

Emerging data support the use of thymidine kinase 1 (TK1) activity as a prognostic marker and for monitoring of response in breast cancer (BC). The long-term prognostic value of TK1 kinetics during ne...