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OB/GYN General

Cigarette Smoking and Estrogen-Related Cancer.

May 17, 2021

Cigarette smoking is a known cause of many cancers, yet epidemiological studies have found protective associations with the risk of four "estrogen-related" malignancies: endometrial cancer, endometrio...

Ovarian cancer population screening and mortality after long-term follow-up in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial.

May 17, 2021

Ovarian cancer continues to have a poor prognosis with the majority of women diagnosed with advanced disease. Therefore, we undertook the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) t...

In vitro effects of aqueous extract of fermented rooibos (Aspalathus linearis) on human sperm function.

May 17, 2021

Aspalathus linearis (rooibos) is a herbal medicinal plant originally from South Africa's fynbos and well known for its medicinal effects in treating different medical conditions. Rooibos contains sign...

Effect of orlistat on live birth rate in overweight or obese women undergoing IVF-ET: A randomized clinical trial.

May 17, 2021

Obesity management prior to infertility treatment remains a challenge. To date, results from randomized clinical trials involving weight loss by lifestyle interventions have shown no evidence of impro...

Cytotoxicity, anti-tumor effects and structure-activity relationships of nickel and palladium S,C,S pincer complexes against double and triple-positive and triple-negative breast cancer (TNBC) cells.

May 17, 2021

Triple-Negative Breast Cancer (TNBC) is a highly aggressive form of breast cancer. The high rate of metastasis associated with TNBC is attributed to its multidrug resistance, making the treatment of t...

Stigma and its influencing factors among breast cancer survivors in China: A cross-sectional study.

May 17, 2021

Although stigma has attracted considerable scholarly attention, few studies have focused on its influencing factors among discharged breast cancer survivors, especially in a Chinese cultural context. ...

Rational design, chemical synthesis and cellular evaluation of novel 1,3-diynyl derivatives of noscapine as potent tubulin binding anticancer agents.

May 17, 2021

We present a new class of derivatives of noscapine, 1,3-diynyl-noscapinoids of an antitussive plant alkaloid, noscapine based on our in silico efforts that binds tubulin and displays anticancer activi...

Pediatric Vulvar Lichen Sclerosus: A Survey of Disease Course.

May 17, 2021

To assess long-term outcomes of Lichen Sclerosus (LS) in the female pediatric population, specifically in relation to patient age, treatment type and duration, and remission.Retrospective chart review...

Evaluation of systemic estrogen for preventing urinary tract infections in postmenopausal women.

May 13, 2021

Current guidelines for postmenopausal recurrent urinary tract infection (rUTI) prevention recommend the use of vaginal topical estrogen products but not systemic estrogens. Studies show that vaginal e...

Paper towel test as independently self-administered to quantify cough-related urine loss: Compliance and comparisons with survey-only data in SWAN.

May 13, 2021

The epidemiologic Study of Women's Health Across the Nation (SWAN) includes urinary incontinence (UI) questionnaire items. We introduced an independently self-administered paper towel test (PTT-ISA; i...

Does traditional pharmacotherapy augment behavioral modification in the treatment of nocturia?

May 13, 2021

To assess the efficacy of traditional first-line non-antidiuretic pharmacotherapy for nocturia in the real-world outpatient urology setting.We retrospectively analyzed voiding diaries from adult men t...

Client satisfaction and experience of telemedicine and home use of mifepristone and misoprostol for abortion up to 10 weeks' gestation at British Pregnancy Advisory Service: a cross-sectional evaluation.

May 13, 2021

Evaluate satisfaction and experience with telemedicine consultation and home use of mifepristone and misoprostol for abortion to 10 weeks' gestation.Cross-sectional evaluation of British Pregnancy Adv...

Late/post-term decidual basalis-derived mesenchymal stem/stromal cells show evidence of advanced ageing and downregulation of microRNA-516b-5p.

May 13, 2021

The placenta is a short-lived organ, yet it shows signs of progressive ageing in the third trimester. Studies of ageing chorionic placental tissue have recently flourished, providing evidence of advan...

Cytogenetic Analysis of the Products of Conception After Spontaneous Abortion in the First Trimester.

May 13, 2021

In the present study, we retrospectively recruited 340 patients who underwent spontaneous abortions to investigate chromosomal abnormalities of the conception products in the first trimester. We also ...

Low-grade serous epithelial ovarian cancer: a comprehensive review and update for radiologists.

May 13, 2021

Low-grade serous carcinoma (LGSC) is an infrequent subtype of ovarian cancer, corresponding to 5% of epithelial neoplasms. This subtype of ovarian carcinoma characteristically has molecular features, ...

LncRNA FGD5-AS1 promotes the malignant phenotypes of ovarian cancer cells via targeting miR-142-5p.

May 13, 2021

Long non-coding RNAs (lncRNAs) have been reported to participate in regulating gene expression and are related to tumor progression. FGD5 antisense RNA 1 (FGD5-AS1) facilitates the progression of vari...

Pelvic Floor Muscle Dysfunctions in Women with Deep Infiltrative Endometriosis: An Underestimated Association.

May 13, 2021

Deep infiltrative endometriosis (DIE) may cause pelvic pain and thus negatively affect the function of different structures. We hypothesized that women with DIE may have dysfunctions of the pelvic flo...

Radiation without endocrine therapy in older women with stage I estrogen-receptor (ER) positive breast cancer is not associated with a higher risk of second breast cancer events.

May 13, 2021

The omission of radiation therapy (RT) in elderly women with stage 1 estrogen-receptor positive (ER+) breast cancer receiving endocrine therapy (ET) is an acceptable strategy based on randomized trial...

Part-time cancers and role of melatonin in determining their metabolic phenotype.

May 13, 2021

This brief review describes the association of the endogenous pineal melatonin rhythm with the metabolic flux of solid tumors, particularly breast cancer. It also summarizes new information on the pot...

The Impact of Platinum-Containing Chemotherapies in Advanced Triple-Negative Breast Cancer: Meta-Analytical Approach to Evaluating Its Efficacy and Safety.

May 13, 2021

Triple-negative breast cancer (TNBC), the most common type of breast cancer, is associated with poor patient prognosis. Platinum-containing chemotherapies are commonly used in the treatment and preven...

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