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OB/GYN General

Prognostic value of insulin resistance in patients with female reproductive system malignancies: A multicenter cohort study.

Jan 01, 2024

Insulin resistance (IR) and systemic inflammation are common in patients with cancer and are associated with poor prognosis. Few studies have reported IR in female reproductive system malignancies. Th...

ChatGPT's performance in German OB/GYN exams - paving the way for AI-enhanced medical education and clinical practice.

Jan 01, 2024

Chat Generative Pre-Trained Transformer (ChatGPT) is an artificial learning and large language model tool developed by OpenAI in 2022. It utilizes deep learning algorithms to process natural language ...

Moesin affects the plasma membrane expression and the immune checkpoint function of CD47 in human ovarian clear cell carcinoma.

Dec 25, 2023

Among major histological subtypes of epithelial ovarian cancer, a higher incidence of ovarian clear cell carcinoma (OCCC) is observed in East Asian populations, particularly in Japan. Despite recent p...

Systemic Inflammatory Patterns in Ovarian Cancer Patients: Analysis of Cytokines, Chemokines, and Microparticles.

Dec 25, 2023

 To compare the patterns of systemic inflammatory response in women with epithelial ovarian cancer (EOC) or no evidence of malignant disease, as well as to evaluate the profile of systemic inflammat...

Endometriosis-related infertility: severe pain symptoms do not impact assisted reproductive technology outcomes.

Dec 25, 2023

Do severe endometriosis-related painful symptoms impact ART live birth rates?Severe pain symptoms are not associated with reduced ART live birth rates in endometriosis patients.ART is currently recogn...

The BRCA2 R2645G variant increases DNA binding and induces hyper-recombination.

Dec 25, 2023

BRCA2 tumor suppressor protein ensures genome integrity by mediating DNA repair via homologous recombination (HR). This function is executed in part by its canonical DNA binding domain located at the ...

Strengthening the Reproductive Endocrinology and Infertility Curriculum Through Three Interactive Cases.

Dec 25, 2023

Improved reproductive endocrinology and infertility (REI) curricula are needed to address educational deficiencies both at our institution and on a national level. To improve REI education for OB/GYN ...

How I Do It: Transcutaneous tibial nerve stimulation TENSI+ system.

Dec 18, 2023

Overactive bladder (OAB) is a common condition that significantly impacts the quality of life (QoL), well-being and daily functioning for both men and women. Among various treatments, peripheral tibia...

Hsa_circ_0013561 promotes epithelial-mesenchymal transition and tumor progression by regulating ANXA2 via miR-23b-3p in ovarian cancer.

Dec 18, 2023

Our preliminary experiment discovered that hsa_circ_0013561 was aberrantly expressed in OC. However, the underlying mechanism is unclear. The expression of hsa_circ_0013561 in OC cells and tissues was...

P53 and TLR4 expression are prognostic markers informing progression free survival of advanced stage high grade serous ovarian cancer.

Dec 18, 2023

New prognostic biomarkers, and bio-signatures, are urgently needed to facilitate a precision medicine-based approach to more effectively treat patients with high-grade serous ovarian cancer (HGSC). In...

Which transfer day results in the highest live birth rate for PCOS patients undergoing in vitro fertilization?

Dec 18, 2023

Polycystic ovary syndrome (PCOS) has unusual levels of hormones. The hormone receptors in the endometrium have a hostile effect and make the microenvironment unfavorable for embryo implantation. The u...

Synthesis of melampomagnolide B derivatives as potential anti-Triple Negative Breast Cancer agents.

Dec 18, 2023

Triple-negative breast cancer (TNBC) is the most malignant and aggressive subtype of breast cancer. Currently, the treatment options to TNBC are limited and the discovery of new drugs and novel therap...

Pelvic floor and sexual function 3 years after hysterectomy - A prospective cohort study.

Dec 11, 2023

Long term effects after hysterectomy, such as a worsening of pelvic floor and sexual function, have been studied with diverse results. Therefore, we investigated the long-term effects of hysterectomy ...

Investigation of intradetrusor onabotulinum toxin A efficacy and safety in older adults with urge urinary incontinence.

Dec 11, 2023

Intradetrusor onabotulinum toxin A (BTX-A) has been demonstrated to be an effective treatment option for overactive bladder (OAB). However, concerns about frailty and frequent injections may deter its...

Abortion restrictions and medical residency applications.

Dec 11, 2023

Residency selection is a challenging process for medical students, one further complicated in the USA by the recent () decision over-ruling the federal right to abortion. We surveyed medical students...

Maternal treatment with selective serotonin reuptake inhibitors during pregnancy and delayed neonatal adaptation: a population-based cohort study.

Dec 11, 2023

Selective serotonin reuptake inhibitor (SSRI) use is common in pregnancy. It is associated with delayed neonatal adaptation. Most previous studies have not adjusted for the severity of maternal mental...

LncRNA HCP5 Facilitates the Progression of Ovarian Cancer by Interacting with the PTBP1 Protein.

Dec 11, 2023

Ovarian cancer (OC) is a major gynecological malignancy with an annually increasing morbidity that poses a significant threat to the health of women worldwide. Most OC patients are diagnosed at an adv...

Multi-Organ Increase in Norepinephrine Levels after Central Leptin Administration and Diet-Induced Obesity.

Dec 11, 2023

Autonomic innervation is important to regulate homeostasis in every organ of the body. The sympathetic nervous system controls several organs associated with metabolism and reproduction, including adi...

Prevalence, diagnostic delay and economic burden of endometriosis and its impact on quality of life: results from an Eastern Mediterranean population.

Dec 11, 2023

There are limited data on endometriosis from the Eastern Mediterranean region. This study for the first time estimates the prevalence and impact of endometriosis on women in Northern Cyprus, an under-...

The Financial Relationship Between the Medical Industry and Residency Leadership in OB/GYN and Urology.

Dec 11, 2023

Industry payments to physicians exceed millions of dollars. Payments can influence physicians' practices and potentially impact trainees. To examine the magnitude of industry payments to obstetrics ...

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