Aug 02, 2021

We aimed to identify randomized clinical trials (RCTs) which evaluated the efficacy of adjunctive psychosocial interventions to improve outcomes during the perinatal period for women with bipolar diso...

Aug 02, 2021

The concurrent existence of Omphalocele and Meckel's diverticulum is not unheard of but is relatively uncommon. A few cases of their coexistence have been reported. Due to the uncommon dual presentati...

Aug 02, 2021

To assess CA 125 and transvaginal ultrasound surveillance in women with BRCA1 or BRCA2 pathogenic variants in a pragmatic clinical setting with>1 year follow up.Retrospective cohort study in a larg...

Aug 02, 2021

To examine whether exposure to ambient ozone, particulate matter with diameter less than 2.5 μm (PM), nitrogen dioxide (NO), and distance to major roadways (DTR) impact ovarian cancer-specific surviv...

Aug 02, 2021

Polyguanine tracts (PolyGs) are short guanine homopolymer repeats that are prone to accumulating mutations when cells divide. This feature makes them especially suitable for cell lineage tracing, whic...

Aug 02, 2021

Studies on immunological infertility after inguinal hernia correction are few and not very representative. Anti-sperm antibodies (ASA) have been shown to reduce male fertility. Although the extent of ...

Aug 02, 2021

Pyrotinib is an irreversible EGFR/HER2 inhibitor, which has been approved for the treatment of breast cancer. The aim of this work was to establish a quantification method for simultaneous determinati...

Aug 02, 2021

Gamma-tocotrienol (γT3) is an analogue of vitamin E with beneficial effects on the immune system, including immune-modulatory properties. This study reports the immune-modulatory effects of daily sup...

Aug 02, 2021

Breast cancer is the most common cancer among females and the leading cause of cancer-related deaths. Approximately 70 % of breast cancers are estrogen receptor (ER) positive. An ER antagonist such ...

Jul 31, 2021

Despite a need for more robust evidence, many patients with chronic pain are being treated with medical cannabis and cannabinoids. In the Journal of Cannabis Research, the Global Task Force on Dosing ...

Jul 29, 2021

Determination of optimal treatment durations for common infectious diseases is an important strategy to preserve antibiotic effectiveness.To determine whether 7 days of treatment is noninferior to 14 ...

Jul 29, 2021

To perform a cost-effectiveness analysis for the surgical and non-surgical management of stress urinary incontinence (SUI) with and without the availability of midurethral sling.Cost-effectiveness ana...

Jul 29, 2021

Exposure to consumer product chemicals during pregnancy may increase susceptibility to pregnancy disorders by influencing maternal inflammation. However, effects on specific inflammatory pathways have...

Jul 29, 2021

Positive ascites cytology is a strong prognostic factor in patients with early-stage ovarian cancer (OvCa). However, limited information is currently available on the impact of positive ascites cytolo...

Jul 29, 2021

Ovarian high grade serous carcinoma (HGSC) is a lethal form of ovarian cancer (OVCA). In most cases it is detected at late stages as the symptoms are non-specific during early stages. Emerging informa...

Jul 29, 2021

Defects in translation lead to changes in the expression of proteins that can serve as drivers of cancer formation. Here, we show that cytosolic NAD synthesis plays an essential role in ovarian cancer...

Jul 29, 2021

In this study, we evaluated the structural features of the endometrial tissues, the immunohistochemical expression of MUC-1, which plays an important role in implantation, and the biochemical markers ...

Jul 29, 2021

Hypoxia has been suggested as an important pathophysiological feature in varicocele disease. On the other hand, the expression of hypoxia-inducible factor 1-alpha (HIF1-α) is associated with the inci...

Jul 29, 2021

Regular physical activity (PA) and healthy body weight have proven benefits on survival in breast cancer (BC) survivors. We aimed to define predictors of long-term PA and weight gain in a representati...

Jul 29, 2021

In this study, eleven new 3- and 7-positions modified scopoletin derivatives (18a-k) were designed, synthesized, and biologically evaluated against human breast cancer cell lines. Most compounds showe...