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OB/GYN General

Efficacy and Safety of Niraparib Plus Bevacizumab as First-Line Maintenance Therapy

Sep 14, 2022

For a study, researchers sought to evaluate the efficacy and safety of niraparib plus bevacizumab as a first-line maintenance treatment for patients with newly diagnosed advanced ovarian cancer. Patie...

The Efficacy and Safety of Pembrolizumab in Patients with Previously Treated Advanced Vulvar Squamous Cell Carcinoma

Sep 14, 2022

For a study, researchers sought to find a few alternatives for treating advanced vulvar carcinoma. Patients in phase 2 multicohort, open-label KEYNOTE-158 study with advanced vulvar squamous cell carc...

TCS Role in Recurrent Epithelial Ovarian Cancer

Sep 14, 2022

Tertiary cytoreductive surgery (TCS) for recurrent ovarian cancer was studied to determine its clinical efficacy. You can search MEDLINE, PubMed, Embase (Elsevier), ClinicalTrials.gov, Scopus (Elsevie...

ECC: LAVRH as a Safe Option for Minimal Invasive Surgery

Sep 14, 2022

Radical hysterectomy and pelvic lymphadenectomy were found to be the gold standard treatments for early-stage cervical cancer  (ECC) in a study. Recent prospective randomized trial results have spark...

Type of Cancer Treatment & Physical Activity with Psychosocial Outcomes

Sep 14, 2022

Although 1 study found a correlation between vigorous exercise and improved cancer survival, it was unclear which patients would reap the greatest benefits from taking up a more active lifestyle. Rese...

MOABP in Ovarian Cancer Debulking

Sep 14, 2022

Ovarian cancer patients who have their bowels removed as part of cytoreductive surgery (CRS) may benefit from a study looking into the aftereffects of this procedure using a combination of mechanical ...

Abdominal Closure Protocol and SSI After Hysterectomy

Sep 14, 2022

The purpose of this study was to examine the relationship between the use of a strategy for abdominal closure and the occurrence of surgical site infection (SSI) in gynecologic oncology patients under...

cN-/pN+ Vulvar Cancer Treatment: Declining Use of IFL

Sep 14, 2022

Researchers found that when sentinel lymph node biopsy (SLNB) results are positive despite clinically negative groin lymph nodes, there is controversy over how to treat vulvar cancer. Inguinofemoral l...

Cervical Cancer Patients Undergoing Surgical Treatment for Early-Stage Disease Are Protected by Preoperative Conization

Sep 13, 2022

The research was set out to determine whether or not pre-operative conization improved disease-free survival (DFS) in early-stage cervical cancer. This population-based cohort study used data from cli...

Seizure Frequency in Pregnancy More Likely With Focal Epilepsy

Aug 26, 2022

Women with focal epilepsy experienced the greatest risk for increased seizure activity in pregnancy and may require closer monitoring in pregnancy and the postpartum period.   “During...

Endometrial HLA-F Expression: Genotypes & Immune cell infiltration

Aug 10, 2022

Extravillous trophoblast cells express the immunomodulatory HLA class Ib molecules HLA-G and HLA-F, interacting with receptors on maternal immune cells. These molecules were found on extravillous trop...

Early Metabolomic Markers Can Predict Gestational Diabetes

Jul 25, 2022

Changes in pregnant women's blood were found in metabolites from early to mid-pregnancy that were linked with the risk for gestational diabetes in later pregnancy. “Gestational diabetes is ty...

Women's AMH Levels Can be Attributed to Three Distinct Genes

Jun 23, 2022

Ovarian follicles expressed AMH in the antral stage of development in females, and variation in age-specific circulating AMH levels was linked to illness outcomes. However, the physiological processes...

Randomized Clinical Research Demonstrates that High-Intensity Exercise Improves Cardiometabolic & Reproductive Outcomes More than Moderate-Intensity Training in Women With the Polycystic Ovarian Syndrome

Jun 23, 2022

It was established that exercise training improved clinical outcomes in women with PCOS, but it was unknown whether HIIT results in better health outcomes than traditional MICT.  Researchers conducte...

Human Sperm Cells Can Produce Paracetamol Metabolite AM404

Jun 23, 2022

According to studies, adult men with high urine levels of the over-the-counter mild painkiller APAP had decreased sperm mobility and a longer time to conception. The study included an in vivo human ph...

Clinical Prediction Model for Predicting the Chance of Successful Medical Treatment of Early Pregnancy Loss

Jun 23, 2022

The success rates of medicinal treatments for EPL were highly variable, both between and within therapy regimens. Although certain predictors were established up to this point, no clinical prediction ...

Cervical Ripening of Synthetic Osmotic Cervical Dilator

Jun 14, 2022

For a study, researchers sought to determine if a synthetic osmotic cervical dilator was as effective as oral misoprostol for cervical ripening. Pregnant women having induction of labor at 37 weeks or...

Fertility Preservation for Transgender Males

Jun 14, 2022

Multiple organizations, including the American Society for Reproductive Medicine, the World Professional Association for Transgender Health, and the Endocrine Society, supported fertility preservation...

Intrapartum Fetal Heart Rate Patterns Unassociated With Recognized Sentinel Events

Jun 14, 2022

The evolution of continuous electronic fetal heart rate (FHR) monitoring has presented the obstetrician with a critical clinical conundrum: basic science observations suggested that such monitoring ma...

Patterns of Sexual Activity & the Development of Sexual Pain

Jun 14, 2022

For a study, researchers sought to investigate whether patterns of sexual intercourse frequency and demographic, menopausal status, genitourinary, health, and psychosocial variables were linked to the...

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