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OB/GYN General

Diagnozing Malignant or Benign Extra-ovarian Condition During Ovarian Follicle Pool Decline

Feb 13, 2023

The following is the summary of “Role of apoptosis and autophagy in ovarian follicle pool decline in children and women diagnosed with benign or malignant extra-ovarian conditions” published in th...

Prevalence of pelvic floor disorders in the Eastern Mediterranean region: A meta-analysis.

Feb 13, 2023

High prevalence of risk factors for pelvic floor disorders (PFD) in the Eastern Mediterranean may result in higher rates of prevalence of PFD in comparison to other regions. Despite individual studies...

Intention matters: Success rate of bilateral salpingo-oophorectomy at the time of vaginal hysterectomy for pelvic organ prolapse.

Feb 13, 2023

The objective of this study was to determine the incidence of successful bilateral salpingo-oophorectomy at the time of vaginal hysterectomy for pelvic organ prolapse and to evaluate associated factor...

Investigating Genetic Determinants of Plasma Inositol Status in Adult Humans.

Feb 13, 2023

Myo-inositol (MI) is incorporated into numerous biomolecules, including phosphoinositides and inositol phosphates. Disturbance of inositol availability or metabolism is associated with various disorde...

Epigenetic alterations impede epithelial-mesenchymal transition by modulating centrosome amplification and Myc/RAS axis in triple negative breast cancer cells.

Feb 13, 2023

Alterations in centrosome proteins may result in centrosome abnormalities such as disorganized spindles and centrosome amplification, leading to aneuploidy and genomic instability. Centrosomes exhibit...

Psychological distress and decision-making factors for prophylactic bilateral mastectomy in cancer-unaffected BRCA1/2 pathogenic variant carriers.

Feb 13, 2023

Women carrying a BRCA1/2 pathogenic variant have increased risk for breast cancer and may opt for risk-reducing bilateral mastectomy. In this study, we examine which demographic, psychosocial, and per...

Evaluation and Management of Early Pregnancy: A Flipped Classroom Case for OB/GYN Clerkship Students.

Feb 13, 2023

Evaluation and management of an early pregnancy diagnosis are clinically pertinent to multiple specialties that will encounter reproductive-age patients. We designed an interactive, small-group, flipp...

Learning Curve for Ultrasound Assessment of Myometrial Infiltration in Endometrial Cancer Visualizing Videoclips: Potential Implications for Training.

Feb 13, 2023

Diagnostic accuracy for estimating myometrial infiltration by ultrasound in endometrial cancer requires experience. The objective of this study is to determine the learning curve (LC) for assessing my...

Analyzing Outcomes Following ART’s in Women Suffering from Cancer

Feb 10, 2023

The following is the summary of “Outcomes after assisted reproductive technology in women with cancer: a systematic review and meta-analysis” published in the January 2023 issue of Human Reproduct...

Spontaneous Preterm Birth: Evaluating Placental Transcriptomic Signatures

Feb 09, 2023

The following is a summary of "Placental transcriptomic signatures of spontaneous preterm birth," published in the January 2023 issue of Obstetrics and Gynecology by Paquette, et al. Most prete...

Weight Loss and Reduced Fetal Growth Velocity with Adverse Perinatal Outcomes in Growth Restricted Fetuses

Feb 08, 2023

The following is a summary of "Reduced fetal growth velocity and weight loss are associated with adverse perinatal outcome in fetuses at risk of growth restriction," published in the January 2023 issu...

All Pregnant, Lactating, and Non-pregnant Women Respond Positively to COVID-19 Booster Dose

Feb 07, 2023

The following is a summary of "COVID-19 booster dose induces robust antibody response in pregnant, lactating, and nonpregnant women," published in the January 2023 issue of Obstetrics and Gynecology b...

Vaginal Hysterectomy with Uterosacral Ligament Suspension Compared to Sacrospinous Hysteropexy with Graft

Feb 06, 2023

The following is a summary of "Characteristics associated with composite surgical failure over 5 years of women in a randomized trial of sacrospinous hysteropexy with graft vs. vaginal hysterectomy wi...

Urinary Incontinence and Prolapse Surgery: Effects of Parity, Pregnancy, and Mode of Delivery

Feb 06, 2023

The following is a summary of "Influence of pregnancy, parity, and mode of delivery on urinary incontinence and prolapse surgery—a national register study," published in the January 2023 issue of Ob...

Assessment of Urinary Level of Neutrophil Gelatinaseassociated Lipocalin (NAGL) in Children with Renal Scar Due to Vesicoureteral Reflux.

Feb 06, 2023

Renal scarring is a serious complications of urinary tract infection and vesicoureteral reflux (VUR). The dimercaptosuccinic acid (DMSA) scan is the gold standard method for diagnosing renal scars but...

A comparison of the perineal and penoscrotal approaches in artificial urinary sphincter implantation for the control of male stress urinary incontinence.

Feb 06, 2023

The two most common surgical approaches to treat stress urinary incontinence in men are the traditional perineal and the new penoscrotal approach for artificial urinary sphincter (AUS) implantation. E...

Factors associated with knowledge about pharmacological management of pregnant women in Peruvian dental students: a logistic regression analysis.

Feb 06, 2023

Clinical management to maintain or restore oral health through the use of drugs during pregnancy is crucial, since at this stage physiological changes significantly influence the absorption, distribut...

Therapeutic effect of haploidentical peripheral blood stem cell treatment on relapsed/refractory ovarian cancer.

Feb 06, 2023

The traditional immunotherapy is limited on relapsed/refractory metastatic ovarian cancer because tumors cause immunosuppression. Since new therapeutic strategies to improve clinical outcomes for pati...

Development and verification of a 7-lncRNA prognostic model based on tumor immunity for patients with ovarian cancer.

Feb 06, 2023

Both immune-reaction and lncRNAs play significant roles in the proliferation, invasion, and metastasis of ovarian cancer (OC). In this study, we aimed to construct an immune-related lncRNA risk model ...

Transcriptomic screening to identify hub genes and drug signatures for PCOS based on RNA-Seq data in granulosa cells.

Feb 06, 2023

Polycystic ovary syndrome (PCOS) is one of the most incident reproductive diseases, and remains the main cause of female infertility. Granulosa cells play a critical role in normal follicle developmen...

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