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OB/GYN General

A case report on the crashing eclamptic patient and a resultingperi-mortem C-section.

Feb 18, 2020

Cardiac arrest in pregnancy is high acuity, low occurrence event. It involves the coordination of multiple teams to take care of ultimately two patients. This is further compounded by physiology that ...

Integrating Screening, Brief Intervention and Referral to Treatment (SBIRT) for Substance Use into Prenatal Care.

Feb 18, 2020

Universal screening for substance use during pregnancy, brief intervention, and referral to treatment (SBIRT) is recommended by ACOG and the USPSTF. Here we present the implementation of SBIRT into th...

Knowledge, attitude, intention, and religion aspect toward fertility preservation among obstetrics and gynecology residents in Indonesia: A cross-sectional study.

Feb 18, 2020

The lack of knowledge from healthcare providers regarding fertility preservation will certainly affect the patient's knowledge, attitude, behavior, and also perspective. Obstetrics and Gynecology (OB/...

Liver Transplantation for Alcoholic Liver Disease: What Is the Risk and Consequence of Relapse?

Feb 18, 2020

Although short- and medium-term outcomes after liver transplantation for alcohol-related liver disease (ARLD) are generally excellent and similar to outcomes for transplantation for other indications,...

The Impact of Skeletal Muscle ERα on Mitochondrial Function and Metabolic Health.

Feb 18, 2020

The incidence of chronic disease is elevated in women after menopause. Increased expression of ESR1 (the gene that encodes the estrogen receptor alpha, ERα) in muscle is highly associated with metabo...

Maternal and Infant Anthropometric Characteristics and Breast Cancer Incidence in the Daughter.

Feb 18, 2020

The intrauterine and early life environments have been linked to the etiology of breast cancer in prior studies. We prospectively examined whether maternal and newborn anthropometric factors as report...

Impact of sex on response to neoadjuvant chemotherapy in patients with bladder cancer.

Feb 18, 2020

To assess the effect of patient's sex on response to neoadjuvant chemotherapy (NAC) in patients with clinically nonmetastatic muscle-invasive bladder cancer (MIBC).Complete pathologic response, define...

Postmenopausal hormone therapy and Alzheimer's disease, dementia, and Parkinson's disease: A systematic review and time-response meta-analysis.

Feb 18, 2020

Hormone therapy continues to be a favourable option in the management of menopausal symptomatology, but the associated risk-benefit ratios with respect to neurodegenerative diseases remain controversi...

Hepatitis C vaccine: 10 good reasons for continuing.

Feb 17, 2020

The introduction of direct-acting antivirals (DAAs) has revolutionized hepatitis C treatment. Short courses of treatment with these drugs are highly beneficial to patients, eliminating the hepatitis C...

Risk factors for hepatocellular carcinoma (HCC) in the northeast of the United States: results of a case-control study.

Feb 17, 2020

HCC incidence has been continuously rising in the US for the past 30 years. To understand the increase in HCC risk, we conducted a case-control study in Connecticut, New Jersey and part of New York C...

Evaluation of Maternal Risk Factors in Neonatal Hyperbilirubinemia.

Feb 17, 2020

Diagnosis and timely treatment of neonatal jaundice and prevention of dangerous side effects of pathologic neonatal jaundice remain a serious debate. The first step in prevention of jaundice is the id...

Immune epigenetic age in pregnancy and one year after birth: Associations with weight change.

Feb 17, 2020

Epigenetic age indices are markers of biological aging determined from DNA methylation patterns. Accelerated epigenetic age predicts morbidity and mortality. Women tend to demonstrate slower blood epi...

Adverse pregnancy outcomes and risk of later allergic rhinitis - Nationwide Swedish cohort study.

Feb 17, 2020

Perinatal conditions may be associated with future allergic disease; however, data are conflicting and incomplete for childhood allergic rhinitis (AR). The aim of this study was to examine pregnancy o...

Chickens bred extensively as sentinels from soil contamination by Toxocara.

Feb 17, 2020

Environmental contamination by Toxocara spp eggs can be verified by parasitological techniques, which are mostly laborious, have low sensitivity, and may require repeated tests to establish the contam...

ABCG2 Overexpression Contributes to Pevonedistat Resistance.

Feb 17, 2020

MLN4924 (pevonedistat) is a first-in-class NEDD8-activating enzyme (NAE) inhibitor in clinical trials for the treatment of solid tumors and hematologic malignancies. Despite the promising activity of ...

Vitamin D Exposure and Ovarian Cancer Risk and Prognosis.

Feb 17, 2020

Given the poor prognosis of ovarian cancer and limited population-level strategies for early detection and long-term treatment success, knowledge of modifiable risk factors for prevention and improved...

TGF-β1 fucosylation enhances the autophagy and mitophagy via PI3K/Akt and Ras-Raf-MEK-ERK in ovarian carcinoma.

Feb 17, 2020

Transforming growth factor-β, a cell secretion factor of the TGF-β superfamily, is involved in the regulation of cell proliferation, differentiation, cytoskeleton formation, migration, invasion and ...

The DNA cytosine deaminase APOBEC3B is a molecular determinant of platinum responsiveness in clear cell ovarian cancer.

Feb 17, 2020

Clear cell ovarian carcinoma (CCOC) is an aggressive disease that often demonstrates resistance to standard chemotherapies. Approximately 25% of CCOC show a strong APOBEC mutation signature. Here, we ...

IL-1 Signaling in Tumor Microenvironment.

Feb 17, 2020

Interleukin 1 (IL-1) has long been known for its pleiotropic effects on inflammation that plays a complex, and sometimes contrasting, role in different stages of cancer development. As a major proinfl...

Low-Dose, Contrast-Enhanced Mammography Compared to Contrast-Enhanced Breast MRI: A Feasibility Study.

Feb 17, 2020

Contrast-enhanced MRI (CE-MRI) is the most sensitive technique for breast cancer detection. Contrast-enhanced mammography (CEM) is emerging as a possible alternative to CE-MRI.To evaluate the diagnost...

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