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OB/GYN General

Long-Term Outcomes of Immediate Autologous Breast Reconstruction for Breast Cancer Patients.

Mar 02, 2020

There is limited information on the oncological outcomes of immediate autologous breast reconstruction in the Asian population. This study aimed to evaluate the oncological outcomes of immediate one-s...

Discovery of T-1101 tosylate as a first-in-class clinical candidate for Hec1/Nek2 inhibition in cancer therapy.

Mar 02, 2020

Highly expressed in cancer 1 (Hec1) plays an essential role in mitosis and is correlated with cancer formation, progression, and survival. Phosphorylation of Hec1 by Nek2 kinase is essential for its m...

The incorporation of cationic property and immunopotentiator in poly (lactic acid) microparticles promoted the immune response against chronic hepatitis B.

Mar 02, 2020

Biodegradable microparticles (MPs) as vaccine adjuvants have sparked the passion of researchers in recent decades. However, it is still a huge challenge to develop an efficient vaccine delivery system...

High varicella-zoster virus susceptibility in Caribbean island populations: implications for vaccination.

Mar 02, 2020

In Caribbean island populations, varicella-zoster virus (VZV) infection is reported regularly among adolescents and adults. Among them, disease more often runs a severe course, causing a substantial b...

Cure of condyloma acuminata covering the glans penis using aminolevulinic acid/photodynamic therapy.

Mar 02, 2020

Condyloma acuminata are a type of verrucous hyperplasia in the genital and perianal areas caused by human papilloma virus (HPV) infection. Traditional treatment methods for condyloma acuminata, such a...

Classification of primary liver cancer with immunosuppression mechanisms and correlation with genomic alterations.

Mar 02, 2020

The tumor microenvironment can be classified into immunologically active "inflamed" tumors and inactive "non-inflamed" tumors based on the infiltration of cytotoxic immune cells. Previous studies on l...

Multivalent DNA vaccine protects against genital herpes by T-cell immune induction in vaginal mucosa.

Mar 02, 2020

Genital herpes is one of the most common sexually transmitted infections (STIs), and it is mainly caused by the neurotropic herpes simplex virus (HSV-2). Not only does this infection cause ulcers, but...

Parameters of Oxidative Stress in Reproductive and Postmenopausal Mexican Women.

Mar 02, 2020

In the reproductive phase, women experience cyclic changes in the ovaries and uterus, and hormones regulate these changes. Menopause is the permanent loss of menstruation after 12 months of amenorrhea...

Exclusion of pregnancy in dialysis patients: diagnostic performance of human chorionic gonadotropin.

Mar 02, 2020

A positive pregnancy test in acute or chronically ill patients has implications for the use of potentially mutagenic or teratogenic products in urgent medical therapies such as the use of chemotherapi...

The Onset of Urinary Incontinence in Different Subgroups and its Relation to Menopausal Status: A Hospital-based Study.

Mar 02, 2020

Numerous risk factors have been reported to influence the development of urinary incontinence (UI). In this study, we took a closer look on the different forms of UI and tried to identify differences ...

Reproductive and hormonal factors and risk of cognitive impairment among Singapore Chinese women.

Mar 02, 2020

Epidemiologic studies suggest that declining estrogen level in menopause may play an important role in the pathogenesis of dementia and contribute to increased risk of cognitive impairment in women. M...

Proteomic serum profile in menstrual-related and post menopause migraine.

Mar 02, 2020

The aim of this pilot study was to analyze the serum proteomic profile of women suffering from menstrual-related migraine (MM group, n = 15) and migraine in post-menopause (PM group, n = 15) in compar...

Comprehensive characterization of endometrial competing endogenous RNA network in infertile women of childbearing age.

Mar 02, 2020

Endometriosis is widely associated with infertility in women of childbearing age, for which there have been no effective treatments. Recent studies suggest that the dysregulation of RNAs contributes t...

Psychiatric comorbidity among women with endometriosis: nationwide cohort study in Sweden.

Mar 02, 2020

Endometriosis is a common gynecological condition affecting women of reproductive age. It has been linked with higher rates of depression and anxiety in small, cross-sectional, and clinical studies. O...

INCREASED RISK OF SEVERE MATERNAL MORBIDITY AMONG INFERTILE WOMEN: ANALYSIS OF US CLAIMS DATA.

Mar 02, 2020

Severe maternal morbidity continues to be an issue of national and global concern and is increasing in incidence. The incidence of infertility is also on the rise, and infertile women experience a hig...

Social Stress & Bone Loss

Mar 02, 2020

Psychosocial stress is an established risk factor for many chronic diseases, with mounting evidence suggesting that stress plays a role in osteoporotic fractures. With a growing aging population, oste...

Guillain-Barré and Acute Transverse Myelitis Overlap Syndrome Following Obstetric Surgery.

Feb 28, 2020

There are rare reports of the occurrence of acute transverse myelitis and Guillain-Barré syndrome after various surgical procedures and general/epidural anaesthesia. The concomitant occurrence of the...

Surgeon's experience and clinical outcome after retropubic tension-free vaginal tape - a case series.

Feb 28, 2020

The retropubic tension-free vaginal tape procedure has been the preferred method for primary surgical treatment of stress and stress-dominant mixed urinary incontinence in women for more than 20 years...

Hepatoprotective effect of total flavonoids of Mallotus apelta (Lour.) Muell.Arg. leaf against carbon tetrachloride-induced liver fibrosis in rats via modulation of TGF-β1/Smad and NF-κB signaling pathways.

Feb 28, 2020

The Mallotus apelta (Lour.) Muell.Arg. is a well-known traditional Chinese medicine (TCM) used for anti-inflammatory, hemostasis and chronic hepatitis.The purpose of this study was to explore the anti...

Sofosbuvir-based regimens in the treatment of patients with chronic hepatitis C virus infection: Real-world efficacy in Thailand.

Feb 28, 2020

To analyze the efficacy and safety of sofosbuvir (SOF)-based regimens in Thai patients with chronic hepatitis C virus infection who had pre-existing significant liver fibrosis.This was a retrospective...

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