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OB/GYN General

IR780 loaded sulfobetaine methacrylate-functionalized albumin nanoparticles aimed for enhanced breast cancer phototherapy.

Apr 22, 2020

New insights about nanomaterials' biodistribution revealed their ability to achieve tumor accumulation by taking advantage from the dynamic vents occurring in tumor's vasculature. This paradigm-shift ...

Advanced oxidation protein products upregulate efflux transporter expression and activity through activation of the Nrf-2-mediated signaling pathway in vitro and in vivo.

Apr 22, 2020

Clinical and benchtop studies suggest that chronic kidney disease (CKD) alters both renal and nonrenal clearance of drugs. Although studies have documented that the accumulating uremic toxins in the b...

Targeting self-assembly peptide for inhibiting breast tumor progression and metastasis.

Apr 22, 2020

The ubiquitous interactions between tumor cells and the surrounding microenvironment contribute to tumor metastasis, interrupting these communications has, therefore, a great potential for antimetasta...

Measures of Patient Dissatisfaction With Health Care in Polycystic Ovary Syndrome: Retrospective Analysis.

Apr 22, 2020

Polycystic ovary syndrome (PCOS) is a common reproductive and metabolic disorder in women; however, many clinicians may not be well versed in scientific advances that aid understanding of the associat...

Temporal Trends of Urogynecologic Mesh Reports to the U.S. Food and Drug Administration.

Apr 14, 2020

To compare temporal trends of urogynecologic mesh medical device reports with sentinel U.S. Food and Drug Administration (FDA) notices and to examine all linked reports of patient death.The Reed Tech ...

Delayed Treatment with Low-Intensity Extracorporeal Shock Wave Therapy in an Irreversible Rat Model of Stress Urinary Incontinence.

Apr 14, 2020

To determine the outcomes and mechanisms of delayed low-intensity extracorporeal shock wave therapy (Li-ESWT) in a rat model of irreversible SUI.Twenty-four female Sprague-Dawley rats were randomly as...

Cost Analysis of Vaginal Anti-Incontinence Procedures at a Tertiary Care Center.

Apr 14, 2020

To compare the cost of three vaginal procedures used in the surgical management of SUI at one tertiary institution.The costs of autologous fascial sling (AFS), synthetic mid-urethral sling (MUS), and ...

A systematic review and meta-analysis of antibiotic resistance patterns, and the correlation between biofilm formation with virulence factors in uropathogenic E. coli isolated from urinary tract infections.

Apr 14, 2020

Urinary tract infection (UTI) is caused by the invasion of the pathogen in the urinary system that can manifest as symptomatic or asymptomatic bacteriuria. This study was conducted to investigate anti...

Zolpidem related persistent genital arousal disorder: An interesting case.

Apr 14, 2020

The present paper is describing a case of persistent genital arousal disorder that developed to a 55-year-old woman, shortly after the initiation of zolpidem. Persistent genital arousal disorder (PGAD...

Trichomonas vaginalis in Pregnancy: Patterns and Predictors of Testing, Infection, and Treatment.

Apr 14, 2020

To identify factors associated with testing for and diagnosis of trichomoniasis in pregnancy and to describe patterns of treatment and tests of reinfection or persistence.We conducted a retrospective ...

The balancing perspective of hard-to-reach hepatitis C patients who were lost to follow-up: A qualitative study.

Apr 14, 2020

In the foreseeable future, patients with hepatitis C virus (HCV) with good healthcare access will all have been cured and the lost to follow-up (LFU) HCV-population will increasingly exist of hard-to-...

Clinical characteristics and immunosuppressants management of coronavirus disease 2019 in solid organ transplant recipients.

Apr 14, 2020

Over 1,000,000 cases of coronavirus disease 2019 (COVID-19) have been confirmed since the worldwide outbreak began. Not enough data on infected solid organ transplant (SOT) recipients are available, e...

Mitochondrial disease disrupts hepatic allostasis and lowers the threshold for immune-mediated liver toxicity.

Apr 14, 2020

In individuals with mitochondrial disease, respiratory viral infection can result in metabolic decompensation with mitochondrial hepatopathy. Here, we used a mouse model of liver-specific Complex IV d...

The increased virulence of hypervirulent fowl adenovirus 4 is independent of fiber-1 and penton.

Apr 14, 2020

Hepatitis-hydropericardium syndrome (HHS) caused by hypervirulent fowl adenovirus 4 (FAdV-4) have been causing great economic losses to Chinese poultry industry since 2015. Elucidation of the pathogen...

Prevalence of preeclampsia and eclampsia in adolescent pregnancy: A systematic review and meta-analysis of 291,247 adolescents worldwide since 1969.

Apr 14, 2020

Hypertensive disorders are among the main causes of maternal and perinatal morbidity and mortality, and the findings regarding the occurrence of preeclampsia (PE) and eclampsia (E) in adolescent pregn...

Single layer suturing in intracapsular myomectomy of intramural myomas is sufficient for a normal wound healing.

Apr 14, 2020

To evaluate surgical outcomes of intracapsular single-layer myomectomy in terms of efficacy and safety as well as examine potential alterations based on kind of surgical approach.A prospective observa...

Adipocytokines are not associated with gestational diabetes mellitus but with pregnancy status.

Apr 14, 2020

Adipose tissue-secreted proteins, i.e. adipocytokines, have been identified as potential mediators linking fat mass and adipose tissue dysfunction with impaired glucose homeostasis, alterations in the...

Artificial intelligence-assisted prediction of preeclampsia: Development and external validation of a nationwide health insurance dataset of the BPJS Kesehatan in Indonesia.

Apr 14, 2020

We developed and validated an artificial intelligence (AI)-assisted prediction of preeclampsia applied to a nationwide health insurance dataset in Indonesia.The BPJS Kesehatan dataset have been prepro...

Maternal arginine supplementation enhances thermogenesis in the newborn lamb.

Apr 14, 2020

Body temperature maintenance is one of the most important physiological processes initiated after birth. Brown adipose tissue (BAT) is an essential mediator of thermogenesis in many species and is res...

A missense mutation of Leu74Pro of OGR1 found in familial amelogenesis imperfecta actually causes the loss of the pH-sensing mechanism.

Apr 14, 2020

Ovarian cancer G protein-coupled receptor 1 (OGR1), also known as GPR68, is a proton-sensing G protein-coupled receptor (GPCR) coupling to G/phospholipase C/Ca signaling pathways. The specific histidi...

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