Efficacy of Upadacitinib in a Randomized Trial of Patients With Active Ulcerative Colitis.
We evaluated the efficacy and safety of upadacitinib, an oral selective inhibitor of Janus kinase...
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The Value of Parental Testing by Next-Generation Sequencing Includes the Detection of Germline Mosaicism.
When a potential disease-causing variant is detected in a proband, parental testing is used to...
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Application of a human mesoderm tissue elongation system in vitro derived from human induced pluripotent stem cells to risk assessment for teratogenic chemicals.
Toxic compounds from the mother’s diet and medication in addition to genetic factors and...
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Epidemiology of pre-eclampsia in the Republic of Kazakhstan: Maternal and neonatal outcomes.
Pre-eclampsia (PE) still significantly contributes to maternal and neonatal morbidity and...
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Pregnancy in Advanced Kidney Disease: Clinical Practice Considerations on a Challenging Combination.
Thanks to the advances in care, pregnancy is now attainable for the majority of young female CKD...
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Role of Frozen Section in Surgical Management of Ovarian Neoplasm.
Cancers of the adnexae, including ovarian and fallopian tube, constitute the eighth most common...
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Comparison of BRCA versus non-BRCA germline mutations and associated somatic mutation profiles in patients with unselected breast cancer.
The data on the phenotypes associated with some rare germline mutations in Chinese breast cancer...
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The contribution of germline predisposition gene mutations to clinical subtypes of invasive breast cancer from a clinical genetic testing cohort.
The germline cancer predisposition genes associated with increased risk of each clinical subtype...
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Improved stability of siRNA-loaded lipid nanoparticles prepared with a PEG-monoacyl fatty acid facilitates ligand-mediated siRNA delivery.
Peptide modification is a popular strategy for developing an active targeting lipid nanoparticle...
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Detection of BRCA1/2 Large Genomic Rearrangement including BRCA1 Promoter-Region Deletions using Next-Generation Sequencing.
Germline mutations in BRCA1 and BRCA2 (BRCA1/2) have been conventionally analyzed by Sanger...
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Is midlife metabolic syndrome associated with cognitive function change? The Study of Women’s Health Across the Nation.
Metabolic syndrome (MetS) affects cognitive function in late-life, particularly in women. But...
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A cumulative index of exposure to endogenous estrogens and breast cancer by molecular subtypes in northern Mexican women.
To evaluate breast cancer (BC) molecular subtypes association with reproductive characteristics...
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Ovariectomy-induced depressive-like behavior and brain glucose metabolism changes in female rats are not affected by chronic mild stress.
The increased incidence of depression in women going through peri-menopause suggests that...
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Ovariectomy provokes inflammatory and cardiovascular effects of endotoxemia in rats: Dissimilar benefits of hormonal supplements.
The female gender is protected against immunological complications of endotoxemia. Here we...
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Impact of Bariatric Surgery on Clinical, Biochemical, and Hormonal Parameters in Women with Polycystic Ovary Syndrome (PCOS).
There is limited data on the impact of bariatric surgery on polycystic ovarian syndrome (PCOS)...
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Management of endometriosis-related infertility: Considerations and treatment options.
Endometriosis is a common inflammatory disease in women of reproductive age and is one of the...
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Disseminated Endometriosis and Low-Grade Endometrioid Stromal Sarcoma in a Patient with a History of Uterine Morcellation for Adenomyosis.
Morcellation of benign uterine tumors allows for removal of the tumors via minimally invasive...
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Producing Parenthood: Islamic Bioethical Perspectives & Normative Implications.
Biomedicine has opened up new possibilities for parenthood. Once resigned to remaining childless...
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A randomized controlled trial of a lifestyle intervention with longitudinal follow up on ovarian dysmorphology in women with polycystic ovary syndrome.
Effects of lifestyle modification on reproductive function in polycystic ovary syndrome (PCOS)...
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Polyamine stimulation perturbs intracellular Ca2+ homeostasis and decreases viability of breast cancer BT474 cells.
Intracellular polyamines such as spermine and spermidine are essential to cell growth in normal...
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