ABCG2 Overexpression Contributes to Pevonedistat Resistance. Feb 17, 2020 MLN4924 (pevonedistat) is a first-in-class NEDD8-activating enzyme (NAE) inhibitor in clinical... Read More
Vitamin D Exposure and Ovarian Cancer Risk and Prognosis. Feb 17, 2020 Given the poor prognosis of ovarian cancer and limited population-level strategies for early... Read More
TGF-β1 fucosylation enhances the autophagy and mitophagy via PI3K/Akt and Ras-Raf-MEK-ERK in ovarian carcinoma. Feb 17, 2020 Transforming growth factor-β, a cell secretion factor of the TGF-β superfamily, is involved in the... Read More
The DNA cytosine deaminase APOBEC3B is a molecular determinant of platinum responsiveness in clear cell ovarian cancer. Feb 17, 2020 Clear cell ovarian carcinoma (CCOC) is an aggressive disease that often demonstrates resistance to... Read More
IL-1 Signaling in Tumor Microenvironment. Feb 17, 2020 Interleukin 1 (IL-1) has long been known for its pleiotropic effects on inflammation that plays a... Read More
Low-Dose, Contrast-Enhanced Mammography Compared to Contrast-Enhanced Breast MRI: A Feasibility Study. Feb 17, 2020 Contrast-enhanced MRI (CE-MRI) is the most sensitive technique for breast cancer detection.... Read More
Cyclins E1 and E2 in ER+ breast cancer: prospects as biomarkers and therapeutic targets. Feb 17, 2020 Cyclin E1 is one the most promising biomarkers in estrogen receptor positive (ER+) breast cancer... Read More
Molecular heterogeneity in breast carcinoma cells with increased invasive capacities. Feb 17, 2020 Background Metastatic progression of breast cancer is still a challenge in clinical oncology.... Read More
Transgelin Silencing Induces Different Processes in Different Breast Cancer Cell Lines. Feb 17, 2020 Transgelin is a protein reported to be a marker of several cancers. However, previous studies have... Read More