PubMed

A 5-step root cause analysis model for test overutilization: A study on its application to plasma transferrin testing.

Mar 7, 2024

This study aimed to develop a root cause analysis (RCA) model for test overutilization, applying it to transferrin overordering at our institution.A comprehensive review was undertaken to establish a systematic RCA model. Upon...

[Clinical features and prognostic analysis of checkpoint inhibitor pneumonitis in patients with non-small cell lung cancer].

Mar 7, 2024

To describe the clinical characteristics of patients with non-small cell lung cancer (NSCLC) who developed checkpoint inhibitor pneumonitis (CIP) and to explore potential prognostic factors. NSCLC patients who were complicated...

Causality of blood metabolites and metabolic pathways on Graves’ disease and Graves’ ophthalmopathy: a two-sample Mendelian randomization study.

Mar 7, 2024

There is ample that metabolic dysregulation is involved in Graves’ disease (GD) and Graves’ ophthalmopathy (GO). Recent studies have identified numerous metabolites associated with GD and GO. However, the causal...

Community-embedded follow-up management intervention for geriatric primary care: a mixed-methods study of an integrated health services model.

Mar 7, 2024

To propose a community-embedded follow-up management model to provide health services for elderly patients with osteoporosis who live alone.Researchers randomly selected 396 people with osteoporosis living alone from five...

Patients’ perspectives on adherence to cardiovascular screening consultation and lifestyle changes.

Mar 7, 2024

Rheumatoid arthritis (RA) poses a significant health burden, with patients facing a twofold higher risk of cardiovascular diseases compared to the general population. As a results, the international recommendations set forth by...

Effect of shift work on excessive daytime sleepiness in female nurses: results from the Japan nurses’ health study.

Mar 7, 2024

We investigated the relationship between shift work and excessive daytime sleepiness (EDS) among participants in the Japan Nurses’ Health Study (JNHS). Responses of 9,728 female nurses to the 6th follow-up questionnaire...

Highgrade cervical lesions diagnosed by methylation in highrisk human papillomavirusinfected patients.

Mar 7, 2024

Currently, traditional cervical cancer screening methods, such as high-risk human papillomavirus testing and liquid based cytology (LBC), still possess limitations. This study aims to identify new diagnostic biomarkers to...

Reproductive outcomes after vaginal repair of isthmocele: A preliminary study and systematic review of the literature.

Mar 7, 2024

Although vaginal repair of isthmocele is an effective and safe surgical option, data on reproductive and obstetrical outcomes are lacking. The aim of this study is to evaluate reproductive outcomes of women undergone vaginal...

Nanomaterial-encapsulated dsRNA of ecdysone-induced early gene E75, a potential RNAi-based SIT strategy for pest control against Bactrocera dorsalis.

Mar 7, 2024

Bactrocera dorsalis is a notorious pest widely distributed across most Asian countries. With the rapid development of pesticide resistance, new pest control methods are urgently needed. RNAi-based sterile insect technique (SIT)...

Cutaneous melanoma in older patients.

Mar 7, 2024

In industrialized countries, the aging population is steadily rising. The incidence of cutaneous malignant melanoma (CMM) is highest in old people. This study focuses on the clinicopathological profile of CMM and indicators of...

Cost-effectiveness of immunotherapies for advanced squamous non-small cell lung cancer: a systematic review.

Mar 7, 2024

There are differences in the pharmacoeconomics of Immune checkpoint blocking (ICB) therapies for the treatment of lung squamous cell carcinoma (LSCC). However, no corresponding review studies have fully discussed the...

[TRANSLATIONAL MEDICINE IN DERMATOLOGY- FURTHER PROMOTING PSORIASIS RESEARCH].

Mar 7, 2024

Psoriasis is a chronic inflammatory skin disorder that affects approximately 2-3% of the population worldwide. Translational medicine, which focuses on treating and analyzing diseases caused by translational factors, is becoming...

he Influence of Academician Franjo Kogoj on Global Dermatology.

Mar 7, 2024

Academician Franjo Kogoj graduated medicine in 1920 in Prague, where he then pursued training in dermatovenerology. During later years, he also visited other dermatology clinics in Europe, where he collaborated with renowned...

Predicting sepsis in-hospital mortality with machine learning: a multi-center study using clinical and inflammatory biomarkers.

Mar 7, 2024

This study aimed to develop and validate an interpretable machine-learning model that utilizes clinical features and inflammatory biomarkers to predict the risk of in-hospital mortality in critically ill patients suffering from...

Gastrosplenic fistula due to splenic lymphoma: two case reports and review of the literature.

Mar 7, 2024

Gastrosplenic fistula is a rare and potentially fatal complication of various conditions. Lymphoma is the most common cause. It can occur spontaneously or after chemotherapy. Gastrosplenic fistula diagnosis can be confused with...

Automated surveillance of non-ventilator-associated hospital-acquired pneumonia (nvHAP): a systematic literature review.

Mar 7, 2024

Hospital-acquired pneumonia (HAP) and its specific subset, non-ventilator hospital-acquired pneumonia (nvHAP) are significant contributors to patient morbidity and mortality. Automated surveillance systems for these...

Impact of a multidisciplinary management team on clinical outcome in ICU patients affected by Gram-negative bloodstream infections: a pre-post quasi-experimental study.

Mar 7, 2024

Bloodstream infections (BSIs) by Gram-negative pathogens play a major role in intensive care patients, both in terms of prevalence and severity, especially if multi-drug resistant pathogens are involved. Early appropriate...

From genome to clinic: The power of translational bioinformatics in improving human health.

Mar 7, 2024

Translational bioinformatics (TBI) has transformed healthcare by providing personalized medicine and tailored treatment options by integrating genomic data and clinical information. In recent years, TBI has bridged the gap...

Noninvasive Assessment of Intracranial Pressure: Deformability Index as an Adjunct to Optic Nerve Sheath Diameter to Increase Diagnostic Ability.

Mar 7, 2024

Today, invasive intracranial pressure (ICP) measurement remains the standard, but its invasiveness limits availability. Here, we evaluate a novel ultrasound-based optic nerve sheath parameter called the deformability index (DI)...

Use of the energy waveform electrocardiogram to detect subclinical left ventricular dysfunction in patients with type 2 diabetes mellitus.

Mar 7, 2024

Recent guidelines propose N-terminal pro-B-type natriuretic peptide (NT-proBNP) for recognition of asymptomatic left ventricular (LV) dysfunction (Stage B Heart Failure, SBHF) in type 2 diabetes mellitus (T2DM). Wavelet...

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