PubMed

Current biology : CB 2013 10 3123(22) 2255-61 doi 10.1016/j.cub.2013.09.019 Abstract Polo-like kinase 4 (Plk4) is a conserved master regulator of centriole assembly. Previously, we found that Drosophila Plk4 protein levels are...

Journal of cell science 121(11) 1771 doi 10.1242/jcs.033340 Abstract

Current biology : CB 2013 10 3123(22) 2245-54 doi 10.1016/j.cub.2013.09.037 Abstract Polo-like kinase 4 (PLK4) is a major player in centriole biogenesis: in its absence centrioles fail to form, while in excess leads to centriole...

Nature communications 2018 05 159(1) 1911 doi 10.1038/s41467-018-04252-2 Abstract CRISPR is becoming an indispensable tool in biological research. Once known as the bacterial immune system against invading viruses, the...

Scientific reports 2018 05 148(1) 7526 doi 10.1038/s41598-018-25919-2 Abstract Coffee’s long-term effect on cognitive function remains unclear with studies suggesting both benefits and adverse effects. We used Mendelian...

Frontiers in physiology 2018 04 269() 403 doi 10.3389/fphys.2018.00403 Abstract The aim of the present work was to perform a meta-analysis evaluating the impact of recovery techniques on delayed onset muscle soreness (DOMS),...

The Journal of clinical investigation 2018 05 14128(6) 2613-2625 doi 10.1172/JCI98769 Abstract Critical immune-suppressive pathways beyond programmed death 1 (PD-1) and programmed death ligand 1 (PD-L1) require greater...

Metabolic engineering 2018 05 16() pii 10.1016/j.ymben.2018.05.005 Abstract The itinerary followed by Pseudomonas putida from being a soil-dweller and plant colonizer bacterium to become a flexible and engineer-able platform for...

Nutrition & metabolism 2018 05 0315() 33 doi 10.1186/s12986-018-0271-1 Abstract Branched-chain amino acids (BCAAs; valine, leucine, and isoleucine) are essential amino acids with protein anabolic properties, which have been...

Cell 2018 05 10173(6) 1508-1519.e18 pii 10.1016/j.cell.2018.04.015 Abstract As predicted by the notion that sister chromatid cohesion is mediated by entrapment of sister DNAs inside cohesin rings, there is perfect correlation...

Nature communications 2018 05 109(1) 1849 doi 10.1038/s41467-018-03917-2 Abstract Although PARP inhibitors (PARPi) target homologous recombination defective tumours, drug resistance frequently emerges, often via poorly...

JAMA 2018 06 07() doi 10.1001/jama.2018.6990 Abstract

Nature 2018 06 06() doi 10.1038/s41586-018-0198-8 Abstract Oxidized phospholipids (OxPL) are ubiquitous, are formed in many inflammatory tissues, including atherosclerotic lesions, and frequently mediate proinflammatory changes...

Nature 2018 06 06558(7708) 73-79 doi 10.1038/s41586-018-0175-2 Abstract Although plasma proteins have important roles in biological processes and are the direct targets of many drugs, the genetic factors that control...

Nature communications 2018 06 069(1) 2197 doi 10.1038/s41467-018-04564-3 Abstract Eukaryotic cells employ the ribosome-associated quality control complex (RQC) to maintain homeostasis despite defects that cause ribosomes to...

Blood 2018 06 08() pii 10.1182/blood-2018-03-840132 Abstract Understanding the profile of oncogene and tumor suppressor gene mutations with their interactions and impact on the prognosis of multiple myeloma (MM) can improve the...

Journal of cognitive neuroscience 2018 06 07() 1-26 doi 10.1162/jocn_a_01291 Abstract The prefrontal cortex (pFC) is central to flexible, goal-directed cognition, and understanding its representational code is an important...

Brain : a journal of neurology 2018 06 05() doi 10.1093/brain/awy146 Abstract Lewy bodies commonly occur in Alzheimer’s disease, and Alzheimer’s disease pathology is frequent in Lewy body diseases, but the burden of...

Nature 2018 06 06() doi 10.1038/s41586-018-0190-3 Abstract Wnt-β-catenin signalling plays a pivotal role in the homeostasis of the intestinal epithelium by promoting stem cell renewal. In the small intestine, epithelial Paneth...

Current opinion in genetics & development 2018 06 0452() 48-56 pii 10.1016/j.gde.2018.05.005 Abstract Genome editing with engineered nucleases (zinc finger, TAL effector, or CRISPR/Cas9-based) enables `write’ access...