Adavosertib with or without olaparib shows efficacy in women with PARP inhibitor-resistant ovarian cancer (Abstract #5505) Clinical trial results from the randomized, non-comparative Phase II EFFORT study showed that...
Read MoreMedian overall survival doubled for veterans with stage 3 non-small cell lung cancer who received chemoradiotherapy plus durvalumab, as compared to those receiving chemoradiotherapy alone, according to a new study presented at...
Read MoreFor a meta-analysis, researchers compared the effect of different non-surgical diabetes prevention strategies on regression to normoglycemia among people with prediabetes. They systematically searched medical literature for...
Read MorePrevious studies have shown that diabetes self-management education and support services empower people with diabetes to follow preventive care practices that reduce disease complications. Investigators who aimed to describe...
Read MoreResearchers hypothesized that US adults with prediabetes and normal BMI develop diabetes through different pathophysiological mechanisms than those with high BMIs and that, therefore, methods of prevention may differ in the...
Read MoreCarbohydrate restriction (CR) confers greater benefit on health outcomes for adults with T2D if done more frequently throughout 1 year. For a study that examined the extent to which ongoing CR is needed to sustain health...
Read MorePrior research indicates that adherence to a Mediterranean (Med) diet pattern, and decreased intake of red/processed meats, refined grains, starches, and added sugars, is associated with reduced cardiometabolic risk independent...
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Given either alone or in combination with chemotherapy PFS, OS not improved, study suggests...
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A study evaluating the utility of novel imaging biomarkers (radiomics) to distinguish patients...
Read MoreSince the 1950s, when the movement disorder tardive dyskinesia (TD) was first described, several drugs have been studied for potential effectiveness or used off-label for the treatment of TD, but none provided clear evidence of...
Read MoreFinal results from the head-to-head ELEVATE-RR Phase III trial of acalabrutinib demonstrated non-inferior progression-free survival (PFS) and statistically significantly fewer events of atrial fibrillation versus ibrutinib in...
Read MoreThe phase III PAOLA-1/ENGOT-ov25 trial evaluated the addition of maintenance olaparib to bevacizumab in women with advanced ovarian cancer who were in response after first-line platinum-based CTx with bevacizumab. In the Phase...
Read MoreClinical trial results from the randomized, non-comparative Phase II EFFORT study showed that adavosertib, a Wee1 inhibitor, was effective in patients with PARP inhibitor-resistant ovarian cancer when given alone and in...
Read MoreTG-1701 (TG Therapeutics) is an investigational, once-daily, selective, convalent, oral Bruton tyrosine kinase inhibitor. Prior research has shown that inhibition of Bruton tyrosine kinase is superior to standard...
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This ongoing trial was presented at the American Society of Clinical Oncology (ASCO) Annual...
Read MoreData indicate that many children with asthma have poorly controlled disease due to poor adherence with inhaled corticosteroids. To determine if an intervention can overcome this barrier, investigators administered a simplified...
Read MoreWhile navigational bronchoscopy (NB) and convex-probe endobronchial ultrasound transbronchial needle aspiration (CP-EBUS-TBNA) are commonly performed in a single setting to evaluate suspicious pulmonary lesions, evidence...
Read MoreEvidence shows that physical exercise can significantly improve exercise tolerance and quality of life in patients with systemic lupus erythematosus (SLE); however its impact on cardiorespiratory fitness in this patient...
Read MorePrior research suggest gender-specific differences in symptom levels and comorbidity prevalence among patients with COPD. Investigators conducted an analysis to determine whether the relationship between these characteristics is...
Read MoreAlthough data indicate that e-cigarettes are the most commonly used tobacco product among adolescents and young adults (AYAs), frequent co-use with combustible cigarettes and cannabis products causes difficulty in disentangling...
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