Meeting Coverage
Conference Highlights: IAS 2021
Jul 27, 2021
New research was presented at IAS 2021, the virtual 11th International AIDS Society Conference on...
Read MoreHighlights from ASCO 2021: Leukemia – eBook
Jul 23, 2021
ASCO Leukemia Annual Meetingv3 Featuring… ELEVATE-RR: Acalabrutinib demonstrates similar...
Read MoreEarly-Stage NSCLC: Promising Data for Neoadjuvant Durvalumab with Stereotactic Body Radiotherapy
Jul 16, 2021
A recently published phase 2 study in Lancet Oncology showed that the combination of neoadjuvant durvalumab with stereotactic body radiotherapy (SBRT) is safe and grants a nearly 55% major pathologic response rates among...
Read MoreT-DXd Combinations in HER2-positive Metastatic Breast Cancer
Jul 14, 2021
The DESTINY-Breast07 trial will test trastuzumab deruxtecan (T-DXd) combinations in patients with HER2-positive advanced or metastatic breast cancer, as a phase 1b/2, open-label, multicenter, dose-finding and dose-expansion...
Read MoreELEVATE-RR: Acalabrutinib demonstrates similar efficacy and better safety compared with ibrutinib
Jul 14, 2021
The phase 3 ELEVATE-RR trial was a head-to-head comparison of acalabrutinib versus ibrutinib in previously treated patients with chronic lymphocytic leukemia. The first results of this study demonstrated that acalabrutinib had...
Read MoreELEVATE-TN: long-term efficacy in chronic lymphocytic leukemia
Jul 14, 2021
Acalabrutinib with or without obinutuzumab demonstrated superior long-term efficacy over obinutuzumab + chlorambucil in patients with chronic lymphocytic leukaemia (CLL). Results from the 4-year follow-up of the ELEVATE-TN study...
Read MoreDurvalumab after chemoradiation proven safe in elderly NSCLC patients
Jul 14, 2021
The addition of durvalumab after chemoradiation (CRT) in unresectable stage 3 non-small cell lung cancer (NSCLC) can be safely delivered in elderly patients ≥70 years with comparable improvement in overall survival (OS), as...
Read MoreDoubling overall survival in US veterans with stage 3 non-small cell lung cancer
Jul 14, 2021
Median overall survival doubled for veterans with stage 3 non-small cell lung cancer who received chemoradiotherapy plus durvalumab, as compared to those receiving chemoradiotherapy alone, according to a new study presented at...
Read MorePreventing interstitial lung disease in patients on trastuzumab detruxtecan
Jul 14, 2021
Results from the phase 2 clinical trial DESTINY-Breast01 showed that the investigational human epidermal growth factor receptor 2 (HER2)-targeted antibody-drug conjugate [Fam-] trastuzumab deruxtecan (T-DXd) has durable...
Read MoreT-DXd Response on Brain Mets HER2+ Breast Cancer
Jul 8, 2021
Results from the phase 2 clinical trial DESTINY-Breast01 showed that the investigational human epidermal growth factor receptor 2 (HER2)-targeted antibody-drug conjugate [Fam-] trastuzumab deruxtecan (T-DXd) has just as durable...
Read More5-year PACIFIC data hold strong in NSCLC
Jul 8, 2021
Updated findings of the PACIFIC trial showed an overall survival (OS) rate of 43% after 5 years of treatment with durvalumab, which has . Physician’s Weekly spoke with Dr. Camille Hertzka, vice president and head of Oncology, US...
Read MoreThe EFFORT needed to overcome PARP resistance in ovarian cancer
Jul 8, 2021
Adavosertib with or without olaparib demonstrated clinical activity with a manageable toxicity...
Read MoreIncorporating New Targeted Therapies for Indolent B-Cell Lymphomas
Jul 1, 2021
For a presentation at ASCO 2021, John Seymour, PhD, Professor at the Peter MacCallum Cancer Centre of the Royal Melbourne Hospital and University of Melbourne in Australia, discussed six FDA-approved agents or drug...
Read MoreConsidering Cellular Therapy for Follicular Lymphoma
Jul 1, 2021
For a review presented at ASCO 2021, Sonali M. Smith, MD, FASCO, Elwood V. Jensen Professor in Medicine and Chief of the Section of Hematology/Oncology at the University of Chicago, discussed the findings of two studies focused...
Read MoreEncouraging Safety & Efficacy Profile for Mono- & Combination Therapy With TG-1701
Jul 1, 2021
TG-1701 (TG Therapeutics) is an investigational, once-daily, selective, convalent, oral Bruton tyrosine kinase inhibitor. Prior research has shown that inhibition of Bruton tyrosine kinase is superior to standard...
Read MoreRacial Disparity Examined in BRCA1/2 Testing in Ovarian Cancer
Jul 1, 2021
Genetic testing for BRCA1/2 mutations is recommended for all women with ovarian cancer, given the important implications for treatment and prognosis, according to the Caitlin E. Taylor, MD, lead author of a paper presented at...
Read MoreRacial Disparities in Ovarian Cancer Treatment and Overall Survival
Jul 1, 2021
It has long been identified that Black women with ovarian cancer have worse overall survival when compared to White women, explains Deanna L Huffman, DO, Department of Internal Medicine, Allegheny Health Network, in Pittsburgh....
Read MorePatient-Centered Communication Can Aid QOL in Women With Ovarian Cancer
Jul 1, 2021
Effective patient-clinician communication (PCC) is central to the delivery of high-quality care, according to the National Cancer Institute (NCI), and it becomes even more crucial in the cancer setting where patients deal with...
Read MoreExamining Treatment Symptom Burden & Management in Ovarian Cancer
Jul 1, 2021
A better understanding of the burden of treatment side effects in patients with gynecological malignancies could help guide symptom interventions and oncologic therapy decision-making, according to Ashley D. Hickman, MD, the...
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