Meeting Coverage

In the phase IV open-label PROTECT trial of pegloticase therapy (pegylated recombinant uricase) in treating severe gout in renal transplant recipients, 89% of patients achieved the primary endpoint of serum uric acid (sUA) less...

We recently spoke with Andrea Lora Kossler, MD, FACS, from the Byers Eye Institute at Stanford University about results from the study “Effect of Teprotumumab on Ocular Surface Disease in Active Thyroid Eye Disease,” which she...

A post-hoc analysis of data from the ORION-9, ORION-10, and ORION-11 trials, presented during the 2021 American Heart Association (AHA) Scientific Sessions, showed that inclisiran treatment every 6 months resulted in effective...

According to a biomarker sub-study of patients with heart failure with reduced ejection fraction (HFrEF) from the DAPA-HF trial, presented during the 2021 American Heart Association (AHA) Scientific Sessions, increases in...

Physician’s Weekly spoke recently with Roman Shinder, MD, FACS, from the Departments of Ophthalmology and Otolaryngology at SUNY Downstate Medical Center, about study results he and his colleague, Anna Artymowicz, MD, presented...

Patients with active psoriatic arthritis are better off with monotherapy with ustekinumab compared with the combination of methotrexate and ustekinumab. The combination causes more side effects and does not enhance efficacy or...

People with difficult-to-treat rheumatoid arthritis who do not have success with one JAK inhibitor could succeed either by cycling to other JAK inhibitors or switching to a biologic. Both strategies led to comparable control of...

Tigulixostat was successfully tested in patients with gout and hyperuricemia for its serum urate-lowering capacity. The drug was overall well tolerated and without particular safety signals. These results support dose finding...

A retrospective chart review analysis in the first 24 hours after hospital admission revealed four predictors that discriminate between children with multisystem inflammatory syndrome and other syndromes: hypotension, abdominal...

Patients with rheumatoid arthritis and associated interstitial lung disease could be safely treated with pirfenidone, the TRAIL1 study showed. In participants receiving the antifibrotic, lung function decline was slowed down,...

A genome-wide association study (GWAS) of dry eye (DE) suggests DE-associated single nucleotide polymorphisms (SNPs) are correlated with increased ocular pain and comorbidities, but not with DE signs, according to study...

Several significant advances have occurred in dry eye disease (DED) treatment in recent years, according to Amy Lin, MD. Including treatments with novel mechanisms of action and delivery systems. “This news is very exciting for...

While high rates of mortality are recognized, data regarding recurrent ischemic events and rehospitalization for heart failure (HF) among patients with HF and acute coronary syndrome (ACS) are limited. Researchers evaluated the...

Approximately 40% of clinically diagnosed patients with heterozygous familial hypercholesterolemia (HeFH) have pathogenic variants of other lipid-related genes in addition to those of conventional FH genes, according to a study....

The normal delay in age of onset of atherosclerotic cardiovascular disease (ASCVD) in women versus men may be shortened in individuals with familial hypercholesterolemia (FH), according to a study. Researchers found that both...

The COVID-19 pandemic resulted in unforeseen changes in healthcare delivery for patients with MS, and the pandemic’s swift progression led to a knowledge gap about how the virus has impacted practice patterns for MS clinicians,...

In a dialysis-dependent population, patients with gout showed a higher cardiovascular comorbidity burden and an increased risk of hospitalization and mortality, compared with patients without gout. In addition, older age,...

Concomitant use of immunomodulators prolonged the effectiveness of pegloticase in patients with uncontrolled gout. Results from a large observational study were consistent with previously conducted smaller trials.1 The...