Quantifying the increased mortality associated with delayed antibiotics in pediatric sepsis
1. Administration of antibiotics beyond 330 minutes from emergency department arrival in pediatric...
Read More
Emergency
Andexanet reduces hematoma expansion in factor Xa inhibitor-associated intracerebral hemorrhage
1. In this randomized controlled trial, among patients presenting with acute intracerebral...
Read More
Early blood-pressure control not associated with improved outcomes in patients with undifferentiated stroke
1. In this randomized controlled trial, patients with stroke symptoms who were given...
Read More
No benefit to fractional flow reserved-guided revascularization in myocardial infarction
1. In this randomized controlled trial, compared to culprit-lesion-only percutaneous coronary...
Read More
Empagliflozin does not decrease risk of hospitalization or death after myocardial infarction
1. In this randomized controlled trial, empagliflozin was not shown to decrease the risk of...
Read More
Decompressive Craniectomy May Benefit Patients With Supratentorial Intracerebral Hemorrhage
1. Fewer patients in the decompressive craniectomy group had an mRS score of 5-6 compared to...
Read More
Nirmatrelvir does not decrease symptom duration in COVID-19
1. In this randomized controlled trial, there was no difference in the median time to sustained...
Read More
Endovascular thrombectomy associated with improved cognitive outcomes for acute ischemic stroke at 5 months
1. In post-stroke patients, endovascular thrombectomy (EVT) was associated with favourable...
Read More
Large language models may be effective in assessing clinical acuity of adult patients in the emergency department
1. The large language model, GPT-4, was capable of assessing clinical acuity when presented with...
Read More
Microaxial flow pump improves infarct-related cardiogenic shock outcomes
1. In this randomized controlled trial, in patients with infarct-relate cardiogenic shock, death...
Read More
Minimally invasive surgery provides functional benefit in acute supratentorial intracerebral hemorrhage
1. In this randomized controlled trial, patients who underwent minimally invasive surgical...
Read More
Endovascular Thrombectomy Post-Large-Vessel Ischemic Stroke Lowers Mortality & Improves Functional Outcomes
Patients in the thrombectomy plus medical care group reported a significantly lower mRS score at...
Read More
Immediate weight-bearing following clavicle fracture fixation with concurrent lower extremity fracture does not change outcomes
1. This retrospective cohort study found that immediate weight-bearing following clavicle fracture...
Read More
Conservative oxygenation improves outcomes in critically ill children on invasive ventilation
1. Duration of organ support or death at 30 days was lower in the conservative oxygenation group...
Read More
Early fixation of extremity fractures may be appropriate for patients with traumatic brain injury
1. In a cohort of patients with traumatic brain injury, early fixation of extremity fractures...
Read More
Tenecteplase is equivalent to placebo between 4.5 and 24 hours after stroke onset
1. In this randomized controlled trial, tenecteplase administered at 4.5 to 24 hours after stroke...
Read More
ED Visits Up for Adults With Diabetes
ED visit rates for adults with diabetes increased from 2012 to 2021, with the highest rates among Black individuals and those with two to four chronic conditions.
Read More
Epinephrine prior to advanced airway management favourable for out-of-hospital cardiac arrest survivability
1. In those with out-of-hospital cardiac arrest (OHCA) and attempted resuscitation by emergency...
Read More
Use of direct oral anticoagulants should not delay surgical intervention for patients with hip fractures
1. In geriatric patients with hip fractures on direct oral anticoagulants (DOACs), surgical...
Read More
Direct Oral Anticoagulants Usage Should Not Delay Surgical Intervention for Patients With Hip Fractures
1. In geriatric patients with hip fractures on direct oral anticoagulants (DOACs), surgical...
Read More