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Critical Care General

PROSPECTIVE, RANDOMIZED EVALUATION of LATISSIMUS DORSI TRANSFER and SUPERIOR CAPSULAR RECONSTRUCTION in MASSIVE, IRREPARABLE ROTATOR CUFF TEARS.

Mar 08, 2021

The treatment of massive, irreparable rotator cuff tears remains controversial today since there is no consensus on the ideal treatment option. This investigation aimed to prospectively evaluate and c...

Dexmedetomidine promotes inflammation resolving through TGF-β1 secreted by F4/80Ly6G macrophage.

Mar 08, 2021

Dexmedetomidine (DEX) is a highly selective α2-adrenoceptor agonist, which can regulate inflammatory responses. However, whether DEX interferes with the inflammation resolving remains unclear. Here, ...

Mycoplasmas bovis P48 induces apoptosis in EBL cells via an endoplasmic reticulum stress-dependent signaling pathway.

Mar 08, 2021

Mycoplasma bovis (M. bovis) is a small bacterium that lacks a cell wall. M. bovis infection can result in chronic pneumonia and polyarthritis syndrome (CPPS), otitis media, conjunctivitis, and meningi...

Causes of Cardiovascular Hospitalization and Death in Patients with Transthyretin Amyloid Cardiomyopathy (From the Tafamidis in Transthyretin Cardiomyopathy Clinical Trial [ATTR-ACT]).

Mar 08, 2021

In the Tafamidis in Transthyretin Cardiomyopathy Clinical Trial (ATTR-ACT), tafamidis significantly reduced mortality and cardiovascular (CV)-related hospitalizations compared with placebo in patients...

The Association of Sleep Apnea and Cardiorespiratory Fitness With Long-Term Major Cardiovascular Events.

Mar 08, 2021

To determine the risk of long-term major adverse cardiovascular events (MACE) when sleep-disordered breathing (SDB) and decreased cardiorespiratory fitness (CRF) co-occur.We included consecutive patie...

Early and Late Outcomes after Transcarotid Revascularisation for Internal Carotid Artery Stenosis: A Systematic Review and Meta-Analysis.

Mar 08, 2021

Transcarotid/transcervical revascularisation (TCAR) is an alternative to carotid endarterectomy (CEA) and transfemoral carotid stenting (tfCAS). This review aimed to evaluate pooled data on patients u...

Overview of Immunological Responses and Immunomodulation Properties of sp.: Prospects for Better Understanding Human Trichuriasis.

Mar 08, 2021

sp. infection has appeared as a pathological burden in the population, but the immunomodulation features could result in an opportunity to discover novel treatments for diseases with prominent inflam...

Body Mass Index and 90-Day Mortality Among 35,406 Danish Patients Hospitalized for Infection.

Mar 08, 2021

To examine the association between body mass index (BMI) and mortality after hospitalization for infection because obesity is associated with increased energy reserves that may protect against death f...

Complications and Soft Tissue Coverage Following Complete Articular, Open Tibial Plafond Fractures.

Mar 08, 2021

To evaluate the incidence of nonunion and wound complications following open, complete articular pilon fractures. Second, to study the effect that both timing of fixation and timing of flap coverage h...

Pediatric minor head injury related return visits to the emergency department and their outcome.

Mar 08, 2021

Minor head injury (MHI) in children is a common emergency department (ED) presentation. It is well established that majority of these patients don't require imaging and can be safely discharged. What ...

Minor head injury transfers: Trends and outcomes.

Mar 08, 2021

Children with traumatic head injury are often transferred from community Emergency Departments (ED) to a Pediatric Emergency Department (PED). The primary objective of this study was to describe the o...

Age at First Exposure to Tackle Football is Associated with Cortical Thickness in Former Professional American Football Players.

Mar 08, 2021

Younger age at first exposure (AFE) to repetitive head impacts while playing American football increases the risk for later-life neuropsychological symptoms and brain alterations. However, it is not k...

AMP-activated protein kinase: a remarkable contributor to preserve a healthy heart against ROS injury.

Mar 08, 2021

Heart failure is one of the leading causes of death and disability worldwide. Left ventricle remodeling, fibrosis, and ischemia/reperfusion injury all contribute to the deterioration of cardiac functi...

An ultrasensitive heart-failure BNP biosensor using B/N co-doped graphene oxide gel FET.

Mar 08, 2021

Heart failure (HF) is the number one cause of death in the world. B-type natriuretic peptide (BNP) is a recognized biomarker for HF and can be used for early detection. Field effect transistor (FET) b...

Development and validation of a liquid chromatography method using UV/fluorescence detection for the quantitative determination of metabolites of the kynurenine pathway in human urine: Application to patients with heart failure.

Mar 08, 2021

Recent evidence indicates the relevant role of the tryptophan (TRP) metabolites in the pathophysiology of cardiovascular diseases via inflammatory and oxidative stress mechanisms. Therefore, quantific...

Thyroid hormone levels as a predictor marker predict the prognosis of patients with sepsis.

Mar 04, 2021

Sepsis is a systemic inflammatory response syndrome with high mortality. There is an upward trend in sepsis prevalence and mortality worldwide. Early and accurate prediction of outcome in sepsis is im...

Hemodynamic support in septic shock.

Mar 04, 2021

The current article reviews recent findings on the monitoring and hemodynamic support of septic shock patients.The ultimate goal of hemodynamic resuscitation is to restore tissue oxygenation. A multim...

Mesenchymal Stromal Cell-Based Therapy: A Promising Approach for Severe COVID-19.

Mar 04, 2021

During the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many critically ill patients died of severe pneumonia, acute respiratory distress syndrome (ARDS), or multiple orga...

Cross-Reactivity of the IDEXX Legiolert Method with Other Gram-Negative Bacteria and Waterborne Pathogens Leads to False Positive Assay Results.

Mar 04, 2021

Legionella species are the causative agent of Legionnaires' disease, a potentially fatal bacterial pneumonia. New regulations and standards have prioritized the development of water safety plans to mi...

Pulmonary Histopathology Findings in Patients With STAT3 Gain of Function Syndrome.

Mar 04, 2021

Multiorgan autoimmunity and interstitial lung disease (ILD) are reported in patients with STAT3 GOF syndrome.We present lung histopathology findings in 3 such children, two of whom underwent wedge bio...

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