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Critical Care General

Clinical utility of CorVue intrathoracic impedance alert with device-measured physical activity in predicting heart failure events.

Mar 18, 2021

Cardiac implantable electronic devices (CIEDs) offer heart failure (HF) diagnostic information, including intrathoracic impedance (ITI) or physical activity (PA). However, few studies have evaluated t...

Actions taken by US hospitals to prepare for increased demand for intensive care during the first wave of COVID-19: A national survey.

Mar 18, 2021

The coronavirus disease 2019 (COVID-19) pandemic placed considerable strain on critical care resources. How United States (U.S.) hospitals responded to this crisis is unknown.What actions did U.S. hos...

The effectiveness of vitamin C for patients with severe viral pneumonia in respiratory failure.

Mar 18, 2021

Vitamin C is a well-known antioxidant and essential cofactor for numerous biological reactions. Several studies reported that vitamin C can improve the symptoms and prognosis of patients with sepsis a...

Comparing Survival by RRT Modality in Patients With Severe Burns

Mar 16, 2021

Findings from numerous studies indicate that patients with burns who develop acute kidney injury (AKI) in the ICU have an increased mortality rate when compared with those who do not develop AKI, expl...

Early life programming of adult ischemic heart disease within and across generations: The role of the socioeconomic context.

Mar 15, 2021

The developmental origins of ischemic heart disease (IHD) have been widely documented but little is known about their persistence across more than one generation. This study aimed to investigate wheth...

Sodium-Glucose Cotransporter-2 Inhibitors and Protection Against stroke in Patients with type 2 Diabetes and Impaired Renal Function: A Systematic Review and Meta-Analysis.

Mar 15, 2021

Recent evidence indicates that treatment with sodium-glucose cotransporter-2 inhibitors (SGLT2i) may favorably affect the risk of stroke in patients with type 2 diabetes mellitus (T2DM) and chronic ki...

Higher BMI Confers a Long-Term Functional Status Advantage in Elderly New Zealand European Stroke Patients.

Mar 15, 2021

Obesity is a risk factor for ischaemic stroke but provides a survival advantage. The relationship between body mass index (BMI) and long-term function is less clear. The presence of an obesity paradox...

Inhibition of endotoxin-induced acute lung injury in rats by bone marrow-derived mesenchymal stem cells: Role of Nrf2/HO-1 signal axis in inhibition of NLRP3 activation.

Mar 15, 2021

Both the Nuclear factor-erythroid 2 p45-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) antioxidant pathway and Nucleotide-binding oligomerization domain (NOD)-like receptor protein 3 (NLRP3) pathway ...

Effect of an emergency department intensive care unit on medical intensive unit admissions and care: A retrospective cohort study.

Mar 15, 2021

Evaluate the impact of an emergency critical care center (EC3) on the admissions of critically ill patients to a critical care medicine unit (CCMU) and their outcomes.This was a retrospective before/a...

A COVID-19 risk score combining chest CT radiomics and clinical characteristics to differentiate COVID-19 pneumonia from other viral pneumonias.

Mar 15, 2021

With the continued transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) throughout the world, identification of highly suspected COVID-19 patients remains an urgent priority. I...

Frequency of ventilator circuit changes to prevent ventilator-associated pneumonia in neonates and children-A systematic review and meta-analysis.

Mar 15, 2021

To assess the effect of different frequencies of ventilator circuit changes in neonates and children through a systematic review and meta-analysis.(1) "No routine change of ventilator circuit (unless ...

Quantitative assessment of COVID-19 pneumonia in neonates using lung ultrasound score.

Mar 15, 2021

Lung ultrasound (LUS) and lung ultrasound score (LUSS) have been successfully used to diagnose neonatal pneumonia, assess the lesion distribution, and quantify the aeration loss. The present study des...

Multidrug-resistant mcr-1 gene-positive Klebsiella pneumoniae ST307 causing urinary tract infection in a cat.

Mar 15, 2021

The Klebsiella pneumoniae (K. pneumoniae) bacterium is responsible for many opportunistic infections such as sepsis, and a multidrug-resistant (MDR) clone sequence type (ST) 307 has recently begun to ...

Probiotic Properties of Alcaligenes faecalis Isolated from Argyrosomus regius in Experimental Peritonitis (Rat Model).

Mar 15, 2021

A strain of Alcaligenes faecalis A12C (A. faecalis A12C) isolated from Argyrosomus regius is a probiotic in fish. Previous experiments showed that A. faecalis A12C had inhibitory effects on the growth...

Infant outcomes and maternal COVID-19 status at delivery.

Mar 15, 2021

To compare clinical characteristics and outcomes of infants born to COVID-19 to non COVID-19 mothers at delivery in a community hospital in Queens, New York.Case-control study conducted March 15 to Ju...

M-CSF, IL-6, and TGF-β promote generation of a new subset of tissue repair macrophage for traumatic brain injury recovery.

Mar 15, 2021

Traumatic brain injury (TBI) leads to high mortality rate. We aimed to identify the key cytokines favoring TBI repair and found that patients with TBI with a better outcome robustly increased concentr...

Differential normal skin transcriptomic response in total body irradiated mice exposed to scattered versus scanned proton beams.

Mar 15, 2021

Proton therapy allows to avoid excess radiation dose on normal tissues. However, there are some limitations. Indeed, passive delivery of proton beams results in an increase in the lateral dose upstrea...

Downregulation of lncRNA KCNQ1OT1 relieves traumatic brain injury induced neurological deficits via promoting "M2" microglia polarization.

Mar 15, 2021

Microglia-induced neuroinflammation is one of the main characteristics of traumatic brain injury (TBI). Presently, we aim to investigate the role of long non-coding RNA (lncRNA) KCNQ1 overlapping tran...

Longitudinal profiling of circulating miRNA during cardiac allograft rejection: a proof-of-concept study.

Mar 15, 2021

Allograft rejection following heart transplantation (HTx) is a serious complication even in the era of modern immunosuppressive regimens and causes up to a third of early deaths after HTx. Allograft r...

Global longitudinal strain in heart failure with reduced ejection fraction: Prognostic relevance across disease severity as assessed by automated cluster analysis.

Mar 15, 2021

Ejection fraction (EF) is still widely used to categorize heart failure (HF) patients but has limitations. Global longitudinal strain (GLS) has emerged as a new prognosticator in HF, independent of EF...

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