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Critical Care General

Clinical presentation of simple and combined or syndromic arteriovenous malformations.

Oct 18, 2021

Arteriovenous malformations of the lower extremities (AVM) can present as simple or complex combined or syndromic forms (e.g. Parkes Weber Syndrome). We aimed to characterize the differences in clinic...

Decompressive Craniectomy After Traumatic Brain Injury: Incorporating Patient Preferences into Decision Making.

Oct 18, 2021

Decompressive craniectomy (DC) is highly effective in relieving intracranial hypertension, however patient selection, intracranial pressure threshold, timing, and long-term functional outcomes, are al...

Mega-dose 90Y-Ibritumomab tiuxetan prior to allogeneic transplantation is effective for aggressive large B-cell lymphoma.

Oct 18, 2021

Allogeneic hematopoietic cell transplantation (allo-HCT) can be curative for relapsed or refractory B-cell lymphomas (BCL), though outcomes are worse in aggressive disease and most patients will still...

How Question Wording & Setting Impacts CKD Awareness

Oct 14, 2021

More than 30 million adults in the United States are affected by CKD, but studies during the past 10-15 years indicate that CKD awareness is suboptimal. “Patient awareness of CKD is a critical first...

Inhaled Nitric Oxide Aids Ventilatory Efficiency & Exercise Capacity in Mild COPD

Oct 11, 2021

“Patients with mild COPD frequently present with chronic dyspnea and poor exercise capacity, often to a greater extent than would be expected based on their resting lung function values,” explains...

Association between platelet count and multiorgan dysfunction and outcomes in patients with sepsis in the pediatric intensive care unit in Saudi Arabia.

Oct 11, 2021

Sepsis is one of the leading causes of morbidity and mortality in the pediatric population worldwide. This study aimed to establish a correlation between platelet count and outcomes of severe sepsis/s...

Molecular identification of Klebsiella pneumoniae and expression of immune genes in infected spotted gar Lepisosteus oculatus.

Oct 11, 2021

Spotted gar (Lepisosteus oculatus) is a primitive ray-finned fish which has not undergone the third round whole genome duplication and commonly used as a model to study the evolution of immune genes. ...

Sex-difference in air pollution-related acute circulatory and respiratory mortality and hospitalization.

Oct 11, 2021

Numerous studies have estimated adverse effects of short-term exposure to ambient air pollution on public health. Few have focused on sex-differences, and results have been inconsistent. The purpose o...

Safety and Efficacy of Single vs Dual Antiplatelets Therapy After Atrial Septal Defect Device Closure.

Oct 11, 2021

Atrial septal defect device closure has become a standard procedure. Antiplatelet therapy is used to prevent thrombus formation in the device. There is no clear recommendation about the antiplatelets ...

WNK3 promotes neuronal survival after traumatic brain injury in rats.

Oct 11, 2021

With-no-lysine kinase 3 (WNK3) is a key regulator of chloride ion transport and neuronal survival in diverse cell types. WNK3 was previously found to regulate the activity of Na-K-2Cl cotransporter-1 ...

Predictors of Mortality, Withdrawal of Life-Sustaining Measures, and Discharge Disposition in Octogenarians with Subdural Hematomas.

Oct 11, 2021

Risk factors for mortality in patients with subdural hematoma (SDH) include poor Glasgow Coma Scale (GCS), pupil non-reactivity, and hemodynamic instability on presentation. Little is published regard...

Handgrip strength to predict extubation outcome: a prospective multicenter trial.

Oct 11, 2021

ICU-acquired weakness (ICUAW) has been shown to be associated with prolonged duration of mechanical ventilation and extubation failure. It is usually assessed through Medical Research Council (MRC) sc...

Endovascular Recanalization of Native Superficial Femoral Artery Chronic Total Occlusion After Failed Bypass Graft: Mid-term Results.

Oct 04, 2021

To evaluate the safety, effectiveness and outcomes of endovascular revascularization of superficial femoral artery (SFA) chronic total occlusion (CTO) in patients with critical limb ischemia (CLI) aft...

Fifteen years single-center experience with In Situ Reconstruction for Infected Native Aortic Aneurysms.

Oct 04, 2021

The purpose of this study was to evaluate survival and freedom from reinfection of patients with infected native aortic aneurysms (INAA) managed with in situ revascularization (ISR), either with open ...

Refinement of microbiota analysis of specimens from patients with respiratory infections using next-generation sequencing.

Oct 04, 2021

Next-generation sequencing (NGS) technologies have been applied in bacterial flora analysis. However, there is no standardized protocol, and the optimal clustering threshold for estimating bacterial s...

Chronic Porphyromonas gingivalis lipopolysaccharide induces adverse myocardial infarction wound healing through activation of CD8+ T-cells.

Oct 04, 2021

Oral and gum health have long been associated with incidence and outcomes of cardiovascular disease. Periodontal disease increases myocardial infarction (MI) mortality by seven-fold through mechanisms...

The First Fatal Case of Chromobacterium violaceum Infection in Japan.

Oct 04, 2021

BACKGROUND Chromobacterium violaceum (C. violaceum) is a gram-negative and facultative anaerobic oxidase-positive bacillus generally seen in tropical or subtropical areas (latitudes between 35°N and ...

STRONG STAR and the consortium to alleviate PTSD: Shaping the future of combat PTSD and related conditions in military and veteran populations.

Oct 04, 2021

The STRONG STAR Consortium (South Texas Research Organizational Network Guiding Studies on Trauma and Resilience) and the Consortium to Alleviate PTSD are interdisciplinary and multi-institutional res...

Role of systemic inflammation in functional recovery, dysphagia, and 1-y mortality in heart failure: A prospective cohort study.

Oct 04, 2021

This study evaluated the relationship between systemic inflammation and clinical outcomes in people hospitalized with acute heart failure (AHF).We prospectively enrolled people newly hospitalized with...

Minocycline attenuates oxidative and inflammatory injury in a intestinal perforation induced septic lung injury model via down-regulating lncRNA MALAT1 expression.

Sep 27, 2021

Oxidative stress and inflammatory responses play an important role in acute lung injury (ALI). Although minocycline (MINO) has anti-inflammatory effects and is a promising candidate in treating inflam...

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