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Critical Care General

FTZ protects against cardiac hypertrophy and oxidative injury via microRNA-214 / SIRT3 signaling pathway.

Feb 21, 2022

Despite the fact that the initial hypertrophic response to ventricular pressure overload is thought to be compensatory, prolonged stress often leads to heart failure. Previous studies have shown that ...

Minocycline Pretreatment Prevents Blood-Brain Barrier Disruption in Septic Rats.

Feb 14, 2022

The aim of the study was to explore the mechanism by which minocycline protects the blood-brain barrier (BBB) in septic rats.A sepsis rat model was generated in healthy, male Sprague-Dawley rats by ce...

Bone mesenchymal stem cell-derived extracellular vesicles inhibit DAPK1-mediated inflammation by delivering miR-191 to macrophages.

Feb 14, 2022

Alveolar macrophage activation and apoptosis are vital contributors to sepsis-associated acute lung injury (ALI). However, the mechanisms of alveolar macrophage activation are yet to be clarified. Dea...

Characterization of Guillain-Barré Syndrome in the Integrated Development Region of the Federal District and Surrounding Areas (RIDE), Brazil, between 2017 and 2019.

Feb 14, 2022

Guillain-Barré Syndrome (GBS) is an acute immune-mediated polyneuropathy that primarily affects the peripheral nerves. Following the Zika virus outbreak in LatinAmerica, all the Latin American and Br...

Critical Preoperative Hemoglobin Value to Predict Anemia-Related Complications After Cardiac Surgery.

Feb 14, 2022

Preoperative anemia is frequent in patients undergoing cardiac surgery and is associated with increased postoperative complications. The purpose of this observational study was to estimate the critica...

Multicentre point-prevalence survey of antibiotic use and healthcare-associated infections in Ethiopian hospitals.

Feb 14, 2022

Effective antimicrobial containment strategies such as Antimicrobial Stewardship Programs (ASPs) require comprehensive data on antibiotics use which are scarce in Ethiopia. This study sought to assess...

Cytomegalovirus Infections in Ugandan Infants: Newborn-Mother Pairs, Neonates with Sepsis, and Infants with Hydrocephalus.

Feb 14, 2022

To estimate the prevalence of cytomegalovirus (CMV) infections in newborn-mother pairs, neonates with sepsis, and infants with hydrocephalus in Uganda.Three populations: (1) newborn-mother pairs, (2) ...

The impact of mild traumatic brain injury on reading comprehension and eye movements: preliminary results.

Feb 14, 2022

Individuals who sustain a mild traumatic brain injury (mTBI) can suffer from executive function, working memory, and attention deficits, which can impact functional task performance, including reading...

Incidence, prevalence, and characteristics of heart failure among patients with multiple sclerosis: A systematic review and meta-analysis.

Feb 14, 2022

Multiple sclerosis (MS) is the most common neurological autoimmune disease. Although it primarily harms the central nervous system, other organs are liable to be affected by it as well. There is a gro...

A scale development study for evaluating the dietary behaviors of patients with heart failure.

Feb 14, 2022

Monitoring the dietary status of patients with heart failure (HF) and preventing malnutrition are of great importance in the prognosis of the disease.The study was conducted to develop a measurement t...

How Data-Driven and Data-Guided Methodologies Help Identify Contemporary Digital Heritage Topics and Trends?

Feb 10, 2022

For a study, it was determined that identifying trends and emerging and declining themes was an essential source of information for academic and innovative management in research and policies. Even th...

Association Between Preinfarction Angina and Culprit Lesion Morphology in Patients With ST-Segment Elevation Myocardial Infarction: An Optical Coherence Tomography Study.

Feb 07, 2022

Previous studies reported the cardiac protection effect of preinfarction angina (PIA) in patients with acute myocardial infarction (AMI). We sought to identify culprit-plaque morphology and clinical o...

Evaluation of procalcitonin (PCT) as a marker of infection in early post living donated liver transplant period.

Feb 07, 2022

Procalcitonin (PCT) has been increasingly used as a biomarker of bacterial infection and as a tool to guide antimicrobial therapy. Despite its increased use, data in patients with solid organ transpla...

When your cat takes you to the ICU: Miller Fisher/ Guillain-Barré-overlap-syndrome caused by Pasteurella multocida infection resembling wound botulism.

Feb 07, 2022

Pasteurella multocida can cause serious soft tissue infections and, less commonly, septic arthritis, osteomyelitis, and sepsis especially in immunocompromised hosts. P. multocida can cause meningitis ...

Role of nitric oxide in convective and diffusive skeletal microvascular oxygen kinetics.

Feb 07, 2022

Progress in understanding physiological mechanisms often consists of discrete discoveries made across different models and species. Accordingly, understanding the mechanistic bases for how altering ni...

#VisualAbstract: Convalescent Plasma Ineffective at Improving Clinical Outcomes or Mortality in Non-Ventilated Patients With COVID-19

Feb 03, 2022

This meta-analysis found that treatment with COVID-19 convalescent plasma (CCP), compared to control group treatment, did not improve clinical outcomes, as measured by the World Health Organizat...

Eosinophil Cell Count Predicts Mortality in the Intensive Care Unit after Return of Spontaneous Circulation.

Jan 31, 2022

Eosinophils constitute 1%-5% of peripheral blood leukocytes, less in the presence of acute infections (referred to as eosinopenia). Studies indicate that eosinopenia can be used as a prognostic predic...

Phylogenetic analysis and antimicrobial susceptibility profile of uropathogens.

Jan 31, 2022

The uropathogens is the main cause of urinary tract infection (UTI). The aim of the study was to isolate bacteria from urine samples of UTI patients and find out the susceptibility of isolated bacteri...

Association of Sex With Stroke and Bleeding Risk of Apixaban and Rivaroxaban in Elderly Atrial Fibrillation Patients Using Propensity Score Weights.

Jan 31, 2022

Evidence from clinical trials suggests a differential effect of sex on the effectiveness and safety of direct oral anticoagulants (DOACs) for stroke prophylaxis in atrial fibrillation (AF).This popula...

Defining Clinical and Microbiological Nonresponse in Ventilator-Associated Pneumonia.

Jan 31, 2022

Ventilator-associated pneumonia (VAP) is a severe complication of mechanical ventilation, with mortality reduced most effectively by adequate early antibiotic treatment. The clinical and microbiologic...

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