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Critical Care General

Ex Vivo Evaluation of Glutamine Treatment in Sepsis and Trauma in a Human Peripheral Blood Mononuclear Cells Model.

Jan 09, 2023

We aimed to assess the lipopolysaccharide (LPS), or heat shock (HS) induction, and glutamine-modulating effects on heat shock protein-90α (HSP90α) and cytokines in an ex vivo model using peripheral ...

Pulmonary manifestations in VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome: a systematic review.

Jan 09, 2023

VEXAS (vacuoles, E1 enzyme, X-linked, auto-inflammatory, somatic) syndrome is a newly described auto-inflammatory disease. Many cases feature pulmonary infiltrates or respiratory failure. This systema...

No "July Effect" in the management and outcomes of acute myocardial infarction: An 18-year United States national study.

Jan 09, 2023

There has been conflicting reports on the effect of new trainees on clinical outcomes at teaching hospitals in the first training month (July in the United States of America). We sought to assess this...

Neutrophil Gelatinase-Associated Lipocalin in Synovial Fluid from Horses with and without Septic Arthritis.

Jan 09, 2023

Neutrophil gelatinase-associated lipocalin (NGAL) has been suggested to be a highly sensitive and specific marker of joint infection in humans. The aim of the study was to investigate NGAL concentrati...

New Child and Adolescent Memory Profile Embedded Performance Validity Test.

Jan 09, 2023

It is essential to interpret performance validity tests (PVTs) that are well-established and have strong psychometrics. This study evaluated the Child and Adolescent Memory Profile (ChAMP) Validity In...

Comparison of Various Metrics of Repetitive Head Impact Exposure And Their Associations With Neurocognition in Collegiate-Aged Athletes.

Jan 09, 2023

Characterize the levels of various metrics of repetitive head impacts (RHI) in contact (CS) and non-contact (NCS) sport athletes and determine the extent to which they are associated with fluid cognit...

New and Persistent Sedative Prescriptions Among Older Adults After Critical Illness: A Population-Based Cohort Study.

Jan 09, 2023

ICU survivors often have complex care needs and can experience insufficient medication reconciliation and polypharmacy. It is unknown which ICU survivors are at risk of new sedative use post-hospitali...

Diabetic Foot Ulcers: Assessing The Quality of Life in Patients

Jan 06, 2023

The following is a summary of "Quality of Life in Patients with Diabetic Foot Ulcers: A Cross-sectional Study," published in the December 2022 issue of Critical care by Dias, et al. For a study...

A Study of Transient and Prolonged Positioning Events Among Nursing Home Residents

Jan 06, 2023

The following is a summary of "Movement Patterns of Transient and Prolonged Positioning Events in Nursing Home Residents: Results from the TEAM-UP Trial," published in the December 2022 issue of Criti...

Management of a Specific Wound Entity in Fungating Malignancies

Jan 06, 2023

The following is a summary of "Fungating Malignancies: Management of a Distinct Wound Entity," published in the December 2022 issue of Critical care by Kondra, et al. For a study, researchers s...

Insights into Prognostication Following Cardiac Arrest: EEG and Evoked Potential Studies

Jan 03, 2023

The following is the summary of “Prognostication after cardiac arrest: how EEG and evoked potentials may improve the challenge” December 2022 Issue of Intensive Care By  Benghanem, et al. ...

Relationship Between SIC and Mortality in Septic Patients

Jan 03, 2023

The following is the summary of “Association of sepsis-induced cardiomyopathy and mortality: a systematic review and meta-analysis” published in the December 2022 Issue of Intensive Care by Lin, ...

Clinical Outcome of wtAE Infection in Patients Treated with β-lactams

Jan 02, 2023

The following is the summary of ‘Clinical outcome of wild-type AmpC-producing Enterobacterales infection in critically ill patients treated with β-lactams: a prospective multicenter study” publis...

ROX Index Predicts Noninvasive Ventilation Failure in Patients

Jan 02, 2023

The following is the summary of “Prediction of noninvasive ventilation failure using the ROX index in patients with de novo acute respiratory failure” published in the  December 2022 issue of Int...

First-time revision knee arthroplasty using a hinged prosthesis : temporal trends, indications, and risk factors associated with re-revision using data from the National Joint Registry for 3,855 patients.

Jan 02, 2023

The aim of this study was to identify variables associated with time to revision, demographic details associated with revision indication, and type of prosthesis employed, and to describe the survival...

Neighborhood disadvantage and immune-related illnesses among residents living in the US Gulf States.

Jan 02, 2023

Neighborhood disadvantage has been associated with increased risk for pneumonia and influenza-associated hospitalizations. Few studies, however, have investigated how neighborhood disadvantage may inf...

Prediction and risk assessment of sepsis-associated encephalopathy in ICU based on interpretable machine learning.

Jan 02, 2023

Sepsis-associated encephalopathy (SAE) is a major complication of sepsis and is associated with high mortality and poor long-term prognosis. The purpose of this study is to develop interpretable machi...

Limits on using the clock drawing test as a measure to evaluate patients with neurological disorders.

Jan 02, 2023

The Clock Drawing Test (CDT) is used as a quick-to-conduct test for the diagnosis of dementia and a screening tool for cognitive impairments in neurological disorders. However, the association between...

Experiences with cross-sectional healthcare and treatment in heart failure patients: implications for medical education.

Jan 02, 2023

to explore how cross-sectional healthcare and treatment is experienced a) by patients with advanced heart failure and multimorbidity and b) by hospital-employed healthcare professionals.Individual tel...

Moral Distress in Canadian Intensivists: A Complex Interplay of Contextual and Relational Factors.

Jan 02, 2023

Healthcare professionals experience moral distress when they cannot act based on their moral beliefs because of perceived constraints. Moral distress prevalence is high among critical care (ICU) clini...

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