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Critical Care General

Prolonged minimal enteral nutrition versus early feeding advancements in preterm infants with birth weight ≤1250 g: a prospective randomized trial.

Jan 30, 2020

To determine the effect of two different feeding strategies on time to achieve full enteral feeding and the incidence of feeding intolerance in preterm infants with birth weight ≤1250 g. A prospe...

Cross-talk between CD38 and TTP Is Essential for Resolution of Inflammation during Microbial Sepsis.

Jan 30, 2020

The resolution phase of acute inflammation is essential for tissue homeostasis, yet the underlying mechanisms remain unclear. We demonstrate that resolution of inflammation involves interactions betwe...

In vitro Evaluation of Linezolid and Doripenem Clearance with Different Hemofilters.

Jan 30, 2020

Renal replacement therapy (RRT) is widely used in the treatment of septic acute kidney injury. However, little is known about how the adsorption properties of hemofilters used in RRT affect antibiotic...

Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia.

Jan 30, 2020

The initial cases of novel coronavirus (2019-nCoV)-infected pneumonia (NCIP) occurred in Wuhan, Hubei Province, China, in December 2019 and January 2020. We analyzed data on the first 425 confirmed ca...

Clinical Risk Factors of Thromboembolic and Major Bleeding Events for Patients with Atrial Fibrillation Treated with Rivaroxaban in Japan.

Jan 30, 2020

It is important to understand the risk of thromboembolism and bleeding in patients with nonvalvular atrial fibrillation (NVAF) receiving direct oral anticoagulants; however, data on risk factors in Ja...

Concentrations of dabigatran administered after acute ischemic stroke.

Jan 30, 2020

The aim of this study was to evaluate the anticoagulation intensity of dabigatran for acute ischemic stroke patients and hemorrhagic/ischemic events after early initiation of dabigatran. Acute ischem...

Outcome of pitavastatin versus atorvastatin therapy in patients with hypercholesterolemia at high risk for atherosclerotic cardiovascular disease.

Jan 30, 2020

There has been no report about outcome of pitavastatin versus atorvastatin therapy in high-risk patients with hypercholesterolemia.Hypercholesterolemic patients with one or more risk factors for ather...

Hormone replacement therapy after surgery for epithelial ovarian cancer.

Jan 30, 2020

Women who have undergone surgical treatment for epithelial ovarian cancer (EOC) may develop menopausal symptoms due to immediate loss of ovarian function following surgery and chemotherapy. Women may ...

Arterial Hypertension & Reduced Glomerular Filtration Rate

Jan 30, 2020

Living kidney donation represents the optimal renal replacement therapy, but recent data suggest an increased long-term renal risk for the donor. Here, we evaluated the risk for reduced estimated glom...

Markers of NETosis Do Not Predict Neonatal Early Onset Sepsis: A Pilot Study.

Jan 30, 2020

Early-onset sepsis in neonates potentially results in substantial morbidity and mortality. A key player in sepsis a neutrophil extracellular traps (NETs) to limit dissemination of pathogens. Aim of t...

Tension-Free Mesh Repair for Incarcerated Groin Hernia: A Comparative Study.

Jan 30, 2020

. Management of emergent groin hernias remains challenging, due to limited consensus in surgical approach and repair options (eg, mesh vs nonmesh, biological mesh, and polypropylene [PP] mesh). . A 5-...

Intravenous immunoglobulin for preventing infection in preterm and/or low birth weight infants.

Jan 30, 2020

Nosocomial infections continue to be a significant cause of morbidity and mortality among preterm and/or low birth weight (LBW) infants. Preterm infants are deficient in immunoglobulin G (IgG); theref...

An Examination of 4 Questions Assessing Self-reported Concussions Among High School Students Participating in Team Sports.

Jan 30, 2020

Current prevalence estimates of youth sports-related concussions are inconsistent because of variation in methodology and potentially unreported concussions.In 2013, Connecticut, Ohio, and Utah each a...

Benefit and harm of intravenous vasodilators across the clinical profile spectrum in acute cardiogenic pulmonary oedema patients.

Jan 30, 2020

The absence of high quality, large-scale data that indicates definitive mortality benefits does not allow for firm conclusions on the role of intravenous vasodilators in acute heart failure. We aimed ...

Many Family Caregivers Never Speak to Health Care Workers

Jan 27, 2020

MONDAY, Jan. 27, 2020 (HealthDay News) -- Many family or unpaid caregivers report never speaking with older adults' health care workers, according to a study published online Jan. 24 in JAMA Network O...

Indoxyl sulfate impairs valsartan-induced neovascularization.

Jan 24, 2020

Studies revealed that the use of renin-angiotensin-aldosterone system antagonism is not associated with a statistically significant reduction in the risk of cardiovascular events in patients with chro...

Longxuetongluo capsule alleviates LPS-induced neuro-inflammation by regulating multiple signaling pathways in BV2 microglia cells.

Jan 24, 2020

Longxuetongluo capsule (LTC), derived from the total phenolic compounds of Chinese dragon's blood, is now used to treatment of ischemic stroke in convalescence. The aim of this study is to explore the...

Use of home negative pressure wound therapy in peripheral artery disease and diabetic limb salvage.

Jan 24, 2020

Use of negative pressure wound therapy (NPWT) in peripheral artery disease (PAD) and diabetic limb salvage (DLS) improves wound healing by providing moist wound conditions, reducing exudate, controlli...

Respiratory support in acute heart failure with preserved vs reduced ejection fraction.

Jan 24, 2020

There is little evidence addressing the use and differential impact of respiratory support in acute heart failure (AHF) patients with preserved (HFPEF) vs reduced (HFREF) ejection fraction. Therefore,...

Evidence-based Clinical Decision Support Systems for the prediction and detection of three disease states in critical care: A systematic literature review.

Jan 24, 2020

Clinical decision support (CDS) systems have emerged as tools providing intelligent decision making to address challenges of critical care. CDS systems can be based on existing guidelines or best pra...

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