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Critical Care General

Presepsin:albumin ratio and C-reactive protein:albumin ratio as novel sepsis-based prognostic scores : A retrospective study.

Feb 18, 2020

To investigate the prognostic value of the presepsin:albumin ratio and C‑reactive protein:albumin ratio in patients with sepsis in the intensive care unit (ICU).A total of 228 (129 males and 99 fem...

Implantation of biologic mesh in ventral hernia repair-does it make sense?

Feb 18, 2020

Biological acellular porcine dermis mesh, such as Permacol™, has been used since 2009 to treat abdominal incisional hernias in a septic context. This study investigated the risk factors for inc...

Low vasopressin and progression of neonatal sepsis to septic shock: a prospective cohort study.

Feb 18, 2020

The study objective was to analyze the association between low plasma vasopressin and progression of sepsis to septic shock in neonates ...

Trajectory of Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock.

Feb 18, 2020

In-hospital pediatric sepsis mortality has decreased substantially, but long-term mortality and morbidity among children initially surviving sepsis, is unknown. Accordingly, the Life After Pediatric S...

Systemic Endothelial Activation Is Associated With Early Acute Respiratory Distress Syndrome in Children With Extrapulmonary Sepsis.

Feb 18, 2020

Systemic endothelial activation may contribute to sepsis-associated organ injury, including acute respiratory distress syndrome. We hypothesized that children with extrapulmonary sepsis with versus wi...

Complement interactions with the pathogenic Neisseriae: clinical features, deficiency states and evasion mechanisms.

Feb 18, 2020

Neisseria gonorrhoeae causes the sexually transmitted infection gonorrhea, while Neisseria meningitidis is an important cause of bacterial meningitis and sepsis. Complement is a central arm of innate ...

Peri- and Post-operative Amplitude-integrated Electroencephalography in Infants with Congenital Heart Disease.

Feb 18, 2020

To identify the factors influencing brain injury in infants with congenital heart disease (CHD) after cardiac surgery.This retrospective study investigated 103 infants with CHD undergoing cardiac surg...

[Treatment strategies and outcomes for injection-associated inguinal perivascular abscesses in intravenous drug addicts].

Feb 18, 2020

Long-term drug users regularly present with deep inguinal vascular-associated abscesses due to continued drug injections utilizing superficial veins. The treatment of these complications continues to ...

Effects of RO27-3225 on neurogenesis, PDGFRβ cells and neuroinflammation after cerebral infarction.

Feb 18, 2020

Cerebral infarction causes severe social and economic burdens to patients due to its high morbidity and mortality rates, and the available treatments are limited. RO27-3225 is a highly selective melan...

Occupant injuries in light passenger vehicles-A NASS study to enable priorities for development of injury prediction capabilities of human body models.

Feb 18, 2020

To prioritize how the development of mathematical human body models for injury prediction in crash safety analysis should be made, the most frequent injuries in the NASS CDS data from 2000 to 2015 wer...

Differential Expression of Circulating Inflammatory Proteins Following Sport-Related Traumatic Brain Injury.

Feb 18, 2020

Sport-related traumatic brain injury (TBI) elicits a multifaceted inflammatory response leading to brain injury and morbidity. This response could be a predictive tool for the progression of TBI and t...

Changes in macrophage inflammatory protein-1 (MIP-1) family members expression induced by traumatic brain injury in mice.

Feb 18, 2020

A deep knowledge of the profound immunological response induced by traumatic brain injury (TBI) raises the possibility of novel therapeutic interventions. Existing studies have highlighted the importa...

Serum Amyloid A is Expressed in the Brain After Traumatic Brain Injury in a Sex-Dependent Manner.

Feb 18, 2020

Serum amyloid A (SAA) is an acute phase protein upregulated in the liver after traumatic brain injury (TBI). So far, it has not been investigated whether SAA expression also occurs in the brain in res...

Short-term effects of low-dose tolvaptan in acute decompensated heart failure patients with severe aortic stenosis: The LOHAS registry.

Feb 18, 2020

Tolvaptan exerts potent diuretic effects in heart failure patients without hemodynamic instability. Nonetheless, its clinical efficacy for acute decompensated heart failure (ADHF) due to severe aortic...

Mechanisms of left ventricular dyssynchrony: A multinational SPECT study of patients with bundle branch block.

Feb 18, 2020

To better understand the mechanisms of left ventricular (LV) mechanical dyssynchrony (LVMD), we explored the relative contributions of QRS duration (QRSd), LV ejection fraction (EF), volumes and scar ...

Incremental value of myocardial wall motion and thickening to perfusion alone by gated SPECT myocardial perfusion imaging for viability assessment in patients with ischemic heart failure.

Feb 18, 2020

The objective of this study was to assess the incremental value of myocardial wall motion and thickening compared with perfusion alone obtained from gated single-photon emission computed tomography (S...

Inpatient Mortality and 30-Day Readmission Rates Associated with Troponin Testing in Patients without Acute Myocardial Infarction.

Feb 18, 2020

Troponin values above the threshold established to diagnose acute myocardial infarction (AMI; >99 percentile) are commonly detected in patients with diagnoses other than AMI. The objective of this stu...

Cardiac protection of Bauhinia championii against reperfusion injury.

Feb 18, 2020

This study aims to investigate the protective effects of the Bauhinia championii (BC) against ischemia/reperfusion (I/R)-induced injury in an isolated heart model. Langendorff-perfused C57BL/6JNarl mi...

Data-driven discovery of changes in clinical code usage over time: a case-study on changes in cardiovascular disease recording in two English electronic health records databases (2001-2015).

Feb 18, 2020

To demonstrate how data-driven variability methods can be used to identify changes in disease recording in two English electronic health records databases between 2001 and 2015.Repeated cross-sectiona...

The First Disease X is Caused by a Highly Transmissible Acute Respiratory Syndrome Coronavirus.

Feb 18, 2020

Based on the announcement of the World Health Organization (WHO) in 2018, the Wuhan pneumonia caused by an unknown etiology should be recognized as the first Disease X. Later, the pathogen was identif...

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