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Critical Care General

Potential of mesenchymal stem cells alone, or in combination, to treat traumatic brain injury.

Mar 12, 2020

Traumatic brain injury (TBI) causes death and disability in the United States and around the world. The traumatic insult causes the mechanical injury of the brain and primary cellular death. While a c...

Traumatic Brain Injury, Working Memory, and Violent Crime in a Sample of U.S. Service Members Involved in the Military Justice System.

Mar 12, 2020

This study examined working memory impairment following mild traumatic brain injury (mTBI) among active duty service members charged with criminal offenses. The prevalence of mTBI among service member...

Changes in Coagulation following Brain Injury.

Mar 12, 2020

Traumatic brain injury (TBI) is a worldwide public health concern due to increasing mortality, affecting around 10 million patients per year. A wide variety of clinical presentations are a function of...

Temporal Changes in Fibrinolysis following Injury.

Mar 12, 2020

Trauma patients present to the emergency department with a spectrum of fibrinolytic activity. This wide variance in fibrinolysis activity is a complex multifactorial process impacted by the degree of ...

Diagnostic analysis of abnormal increase of PASP in fetus in middle- and late-stage pregnancy by color Doppler echocardiography.

Mar 12, 2020

Our study was conducted with an attempt to investigate the diagnostic analysis of abnormal increase of fetal pulmonary artery systolic pressure in middle and late pregnancy by color Doppler echocardio...

Reactive oxygen species and nitric oxide imbalances lead to in vivo and in vitro arrhythmogenic phenotype in acute phase of experimental chagas disease.

Mar 12, 2020

Chagas Disease (CD) is one of the leading causes of heart failure and sudden death in Latin America. Treatments with antioxidants have provided promising alternatives to ameliorate CD. However, the sp...

Outcome differences in acute vs. acute on chronic heart failure and cardiogenic shock.

Mar 12, 2020

Despite advances in coronary reperfusion and percutaneous mechanical circulatory support, mortality among patients presenting with cardiogenic shock (CS) remains unacceptably high. Clinical trials and...

Variation in clinical and patient-reported outcomes among complex heart failure with preserved ejection fraction phenotypes.

Mar 12, 2020

The aim of this study is to use six previously described heart failure with preserved ejection fraction (HFpEF) phenotypes to describe differences in (i) the biological response to spironolactone, (ii...

Remote blood pressure monitoring and behavioral intensification for stroke: A randomized controlled feasibility trial.

Mar 12, 2020

Measuring blood pressure (BP) at home and remote monitoring can improve the patient's adherence to BP control and vascular outcomes. This study evaluated the feasibility of a trial regarding the effec...

Use of Electronic Health Records by Older Adults, 85 Years and Older, and Their Caregivers.

Mar 12, 2020

Healthcare providers may not offer patient portal (PP) access to electronic health records (EHRs) to their patients older than 85 years, due to the false impression that they do not utilize technolo...

Effectiveness of inactivated influenza vaccine in autoimmune rheumatic diseases treated with disease-modifying anti-rheumatic drugs.

Mar 12, 2020

The effectiveness of inactivated influenza vaccine in people with autoimmune rheumatic disease (AIRDs) is not known. We investigated whether the influenza vaccine is effective in preventing respirator...

Addressing Global Infectious Diseases With Dual Infectious Diseases/Critical Care Medicine Fellowships

Mar 12, 2020

The discipline of infectious diseases is ever-growing, with a spectrum of practice pathways adopted by ID physicians, including sub-specialized fields of expertise in public health, hospital epidemio...

Daily Rounding Helps Curb CAUTIs in Pediatric ICU Patients

Mar 11, 2020

WEDNESDAY, March 11, 2020 (HealthDay News) -- Targeted rounding for pediatric patients with an indwelling urinary catheter is an effective and sustainable strategy to reduce catheter-associated urinar...

Comparing TEE vs Non-TEE guided cardioversion of atrial fibrillation: the ENSURE-AF trial.

Mar 10, 2020

ENSURE-AF (NCT02072434) assessed therapy with edoxaban versus enoxaparin-warfarin in patients with nonvalvular atrial fibrillation (AF) undergoing elective electrical cardioversion (ECV).To evaluate c...

Lumbar Puncture Guidance

Mar 09, 2020

Data indicate that nearly 400,000 lumbar punctures (LPs) are performed annually for either diagnostic workup or therapeutic relief in the United States. Regular referral to radiology for assistance ...

Development of a novel minimally invasive technique to washout necrotic bone marrow content from epiphyseal bone: A preliminary cadaveric bone study.

Mar 09, 2020

Legg-Calvé-Perthes disease is a juvenile ischemic osteonecrosis which produces extensive necrotic cell debris and release of damage associated molecular patterns (DAMPs) in the femoral head. The necr...

Risk factors for ischemic complications in vascular reconstructive surgeries.

Mar 09, 2020

There have been reports on postoperative ischemic complications with vascular reconstructive surgery. However, various factors, such as lesions, operative technique, and perioperative treatment, preve...

Revascularization and limb salvage following critical limb ischemia by nanoceria-induced Ref-1/APE1-dependent angiogenesis.

Mar 09, 2020

In critical limb ischemia (CLI), overproduction of reactive oxygen species (ROS) and impairment of neovascularization contribute to muscle damage and limb loss. Cerium oxide nanoparticles (CNP, or 'na...

Thyroid-related hormones as potential markers of hypoxia/ischemia.

Mar 09, 2020

This study aimed to investigate the usefulness of the thyroid-related hormones as markers of acute systemic hypoxia/ischemia to identify deaths caused by asphyxiation due to neck compression in human ...

Enasidenib in patients with mutant IDH2 myelodysplastic syndromes: a phase 1 subgroup analysis of the multicentre, AG221-C-001 trial.

Mar 09, 2020

Mutations in isocitrate dehydrogenase-2 (IDH2) occur in around 5% of patients with myelodysplastic syndromes. Neomorphic activity of mutant IDH2 proteins results in hypermethylation of DNA and histone...

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