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Critical Care General

EMMPRIN/CD147 plays a detrimental role in clinical and experimental ischemic stroke.

Mar 20, 2020

Ischemic stroke is a devastating disease, often resulting in death or permanent neurological deficits. EMMPRIN/CD147 is a plasma membrane protein that induces the production of matrix metalloproteinas...

Aortic stiffness and related complications after endovascular repair of blunt thoracic aortic injury in young patients.

Mar 20, 2020

: This study aimed to evaluate the changes in aortic stiffness in young patients undergoing thoracic endovascular aortic repair (TEVAR) after blunt thoracic aortic injury (TBAI) and to examine the ass...

Pterostilbene improves cardiac function in a rat model of right heart failure through modulation of calcium handling proteins and oxidative stress.

Mar 20, 2020

This study explored the effect of pterostilbene (PTS) complexed with hydroxypropyl-β-cyclodextrin (HPβCD) on right heart function, glutathione and glutaredoxin systems and the expression of intracel...

The improvement of the shear stress and oscillatory shear index of coronary arteries during Enhanced External Counterpulsation in patients with coronary heart disease.

Mar 20, 2020

Enhanced External Counterpulsation (EECP) can chronically relieve ischemic chest pain and improve the prognosis of coronary heart disease (CHD). Despite its role in mitigating heart complications, EEC...

Anaphylactic cardiovascular collapse manifesting as myocardial infarction following salad consumption. A case of Kounis variant type I syndrome.

Mar 20, 2020

Anaphylactic cardiovascular events constitute an underrated cause of medical emergencies in hospitalized patients. Coronary arteries and myocardium are targeted by anaphylactic mediators leading to ac...

The value of chest magnetic resonance imaging compared to chest radiographs with and without additional lung ultrasound in children with complicated pneumonia.

Mar 20, 2020

In children with pneumonia, chest x-ray (CXR) is typically the first imaging modality used for diagnostic work-up. Repeated CXR or computed tomography (CT) are often necessary if complications such as...

[Antibiotic Stewardship in Community-Acquired Pneumonia].

Mar 20, 2020

Antibiotic stewardship (ABS) denotes structured and continuous measures to improve the quality of prescribing anti-infectives. The aim is to achieve optimal treatment results and to minimize undesirab...

Digestive Symptoms Reported for About Half of COVID-19 Patients

Mar 19, 2020

THURSDAY, March 19, 2020 (HealthDay News) -- Patients with coronavirus 2019 (COVID-19) frequently have digestive symptoms, and those with digestive symptoms have a worse clinical outcome, according to...

Asthma-Related ED Visits in Children With Depression & Anxiety

Mar 18, 2020

Research indicates that adults with asthma as well as depression, anxiety, or both demonstrate higher asthma-related healthcare use, including emergency department (ED) visits. Naomi S. Bardach, MD, ...

Insulin Autoimmune Syndrome: A Case of Clopidogrel-induced Autoimmune Hypoglycemia.

Mar 18, 2020

Insulin autoimmune syndrome (IAS) is characterized by hyperinsulinemic hypoglycemia with elevated anti-insulin antibodies. Most commonly observed in the Japanese population, elsewhere it is rare and a...

Oral high dose vitamin B12 decreases renal superoxide and post-ischemia/reperfusion injury in mice.

Mar 18, 2020

Renal ischemia/reperfusion injury (IRI) is a leading cause of acute kidney injury (AKI), a potentially fatal syndrome characterized by a rapid decline in kidney function. Excess production of superoxi...

25-Hydroxy Vitamin D Deficiency Is Associated With Cardiovascular Sequential Organ Failure Assessment and Pediatric Risk of Mortality III Scores in Critically Ill Children.

Mar 18, 2020

Investigate 25-hydroxy vitamin D (25(OH)D) levels and the correlation with cardiovascular sequential organ failure assessment (CV-SOFA) and pediatric risk of mortality III (PRISM-III) scores in criti...

LncRNA CYTOR attenuates sepsis-induced myocardial injury via regulating miR-24/XIAP.

Mar 18, 2020

This work aims to investigate the function and mechanism of long non-coding RNA (lncRNA) cytoskeleton regulator RNA (CYTOR) in myocardial injury induced by sepsis. The sepsis-induced myocardial injury...

Bacterial contamination rate of platelet components by primary culture: a systematic review and meta-analysis.

Mar 18, 2020

Platelets have the highest bacterial contamination risk of all blood components, and septic transfusion reactions remain a problem. A good estimate of contamination rates could provide information abo...

Impact of the pre-illness lipid profile on sepsis mortality.

Mar 18, 2020

To determine if baseline lipid levels contribute to the relationship between lipid levels during sepsis and outcomes.We conducted a retrospective cohort study at a tertiary-care academic medical cente...

A guideline for homology modeling of the proteins from newly discovered betacoronavirus, 2019 novel coronavirus (2019-nCoV).

Mar 18, 2020

During an outbreak of respiratory diseases including atypical pneumonia in Wuhan, a previously unknown β-coronavirus was detected in patients. The newly discovered coronavirus is similar to some β-c...

Platelet-to-lymphocyte ratio is associated with prognosis in patients with Corona Virus Disease-19.

Mar 18, 2020

SinceDecember 2019, novelcoronavirus infected pneumonia emerged in Wuhan city and rapidly spread throughout China. In severe novel coronavirus pneumonia cases, the number of platelets, their dynamic c...

Epidemiology and effective pertussis vaccination of hospitalized children at Vietnam National Children's Hospital, 2015 - 2018.

Mar 18, 2020

Evaluate effect and costs of pertussis vaccination at Vietnam national children's hospital.Pertussis cases were defined by positive laboratory tests of children under 5 years January 2015 - June 2018,...

Circ_0038467 regulates lipopolysaccharide-induced inflammatory injury in human bronchial epithelial cells through sponging miR-338-3p.

Mar 18, 2020

Pneumonia is a common acute lower respiratory infection in children and elders. Circular RNAs (circRNAs) have recently been uncovered to play important roles in pneumonia. However, the function and me...

Uncovering sex-specific mechanisms of action of testosterone and redox balance.

Mar 18, 2020

The molecular and pharmacological manipulation of the endogenous redox system is a promising therapy to limit myocardial damage after a heart attack; however, antioxidant therapies have failed to full...

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