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Critical Care General

Furosemide exacerbated the impairment of renal function, oxygenation and medullary damage in a rat model of renal ischemia/reperfusion induced AKI.

May 01, 2023

Perioperative acute kidney injury (AKI) caused by ischemia-reperfusion (IR) is a significant contributor to mortality and morbidity after major surgery. Furosemide is commonly used in postoperative pa...

Skin biopsy in adult patients with meningococcal purpura fulminans: a multicenter retrospective cohort study.

May 01, 2023

Neisseria meningitidis is the leading responsible bacterium of Purpura Fulminans (PF) accounting for two thirds of PF. Skin biopsy is a simple and minimally invasive exam allowing to perform skin cult...

Does Preterm Status Hinder the Timely Diagnosis of Intestinal Atresia?

May 01, 2023

Intestinal atresia is one of the most common causes of bowel obstruction in newborns. Unfortunately, this diagnosis is often missed or delayed in extremely preterm infants because of complications of ...

Systematic review of economic evaluations for paediatric pulmonary diseases.

May 01, 2023

Paediatric pulmonary diseases are the leading causes of mortality amongst children under five globally. Economic evaluations (EEs) seek to guide decision-makers on which health care interventions to a...

Case report: therapeutic monitoring of vancomycin in an acute liver failure patient with anuria under high-flow continuous hemodiafiltration.

May 01, 2023

High-flow continuous hemodiafiltration (HF-CHDF) combines diffusive and convective solute removal and is employed for artificial liver adjuvant therapy. However, there is no report on dosage planning ...

Early diagnosis leading to improvement of critical illness polyneuropathy associated with severe Staphylococcus aureus infection in a patient on hemodialysis.

May 01, 2023

Critical illness polyneuropathy (CIP) is a very rare complication of sepsis and multi-organ failure. Herein, we report the first case of CIP reported in a patient on maintenance hemodialysis, who impr...

Registry Data Show Complication Rates and Cost in Revision Hip Arthroplasty.

May 01, 2023

Revision THA (rTHA) places a burden on patients, surgeons, and health care systems because outcomes and costs are less predictable than primary THA. The purposes of this study were to define indicatio...

Prenatal diagnosis of isolated coronary artery fistula: systematic review, analysis of perinatal prognostic factors and case report.

May 01, 2023

Isolated coronary artery fistula (CAF) is a rare entity in which evidence for both prognosis and need for perinatal treatment is lacking. We aim to evaluate the characteristics, evolution and perinata...

ICU-acquired Pneumonia: Definitions, Incidence, Prevalence, and Mortality

Apr 27, 2023

The following is a summary of “Definitions, rates and associated mortality of ICU-acquired pneumonia: A multicenter cohort study,” published in the April 2023 issue of Critical Care by Johnstone e...

Clostridioides Difficile Infection among Critically Ill Patients on Mechanical Ventilation

Apr 27, 2023

The following is a summary of “Clostridioides difficile infection in mechanically ventilated critically ill patients: A nested cohort study,” published in the April 2023 issue of Critical Care by ...

Moderate-to-Severe COPD: Therapeutic Response to SITT

Apr 24, 2023

The following is a summary of “Therapeutic Response to Single-Inhaler Triple Therapies in Moderate-to-Severe COPD,” published in the March 2023 issue of Respiratory Care by Ohtsuka et al.  ...

[Influencing factors of small intestinal ischemia in elderly patients with incarcerated hernia].

Apr 24, 2023

To investigate the factors influencing small intestinal ischemia in elderly patients with incarcerated hernia. The clinical data of 105 elderly patients admitted for surgical procedures of incarcera...

Rnf144b alleviates the inflammatory responses and cardiac dysfunction in sepsis.

Apr 24, 2023

Sepsis is an inflammatory disease with high mortality and morbidity. Inflammation plays an essential role in sepsis, and suppressing inflammation has been shown to ameliorate sepsis. Rnf144b is an ubi...

Activities of a broad-spectrum antimicrobial peptide analogue SAMP-A4-C8 and its combat against pneumonia in Staphylococcus aureus infected mice.

Apr 24, 2023

Antimicrobial peptides and their analogues have become substitutes for antibiotics in recent years. The antimicrobial peptide analogue SAMP-A4-C8 (n-octanoic-VRLLRRRI) with high antimicrobial activity...

Effect of low-to-moderate hyperoxia on lung injury in preclinical animal models: a systematic review and meta-analysis.

Apr 24, 2023

Extensive animal investigation informed clinical practice regarding the harmful effects of high fractional inspired oxygen concentrations (FiOs > 0.60). Since questions persist whether lower bu...

Single versus dual antibiotic regimen in women with term prolonged rupture of membranes and intrapartum fever: a retrospective study.

Apr 24, 2023

The impact of E. coli in causing peripartum infections has been increasing due to rising ampicillin resistance. In this study, we compared maternal and neonatal outcomes of women with prolonged ruptu...

Identification of a novel gene signature for the prognosis of sepsis.

Apr 24, 2023

Sepsis is a life-threatening organ dysfunction caused by the host's dysfunctional response to infection, and its pathogenesis is still unclear. In view of the complex pathological process of sepsis, f...

Traumatic brain injury as a chronic disease: insights from the United States Traumatic Brain Injury Model Systems Research Program.

Apr 24, 2023

Traumatic brain injury (TBI) is a global health priority, associated with substantial burden. Historically conceptualised as an injury event with finite recovery, TBI is now recognised as a chronic co...

Impact of NIV on Oxygen Levels in Peripheral and Respiratory Muscles During High-intensity Exercise

Apr 21, 2023

The following is a summary of “ Effect of Adding Non-invasive Ventilation to High-Intensity Exercise on Peripheral and Respiratory Muscle Oxygenation," published in the March 2023 issue of Respirato...

Assessing Postextubation Stridor: The Role of Risk Stratification and Cuff Leak Testing

Apr 20, 2023

The following is a summary of “Utilization of a Risk Stratification Tool and Volume-Based Cuff Leak Test to Assess Postextubation Stridor," published in the March 2023 issue of Respiratory Care by ...

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