Apr 06, 2020

Previous work by our group has shown the pro-differentiating effects of apotransferrin (aTf) on oligodendroglial cells in vivo and in vitro. Further studies showed the remyelinating effect of aTf in a...

Apr 06, 2020

E3 ubiquitin ligase gene, WWP2, is associated with acute kidney injury (AKI). This research was conducted to explore the role of WWP2 in AKI. AKI cell model was produced in human renal proximal tubula...

Apr 06, 2020

Aimed to balance the maximization of oncological results with the minimization of the surgery related impact on patient's quality of life and cosmetic, in 2018, the da Vinci Single-Port (SP) system wa...

Apr 06, 2020

This study used constitutive CD226 gene knockout (KO) mice as a model to investigate the functions and mechanisms of CD226 in megakaryocyte (MK) maturation and platelet activation. Although CD226 defi...

Apr 06, 2020

Sepsis is a potentially fatal complication of infections and there are currently no effective therapeutic options for severe sepsis. In this study, we revealed the secretion mechanism of transforming ...

Apr 06, 2020

The aim: To conduct an analysis of the complex treatment of severe forms of rectal abscesses complicated by NF.Materials and methods: The results of treatment in 471 patients with deep forms of RA was...

Apr 06, 2020

Curcumin derivatives have been shown to inhibit replication of human influenza A viruses (IAVs). However, it is not clear whether curcumin and its derivatives can inhibit neuraminidase (NA) of influen...

Apr 06, 2020

Autosomal dominant hyper IgE syndrome (AD-HIES) caused by STAT3 gene mutation is a rare primary immunodeficiency disease. To better understand the disease, we described the clinical characteristics of...

Apr 06, 2020

Avian influenza A(H5N6) keeps evolving, causing outbreaks in birds and sporadic infections in human. Here we report a fatal pediatric infection caused by a novel reassortant H5N6 virus. The patient wa...

Apr 06, 2020

Non-alcoholic fatty liver disease (NAFLD) and human immunodeficiency virus (HIV) are independently associated with cardiovascular disease (CVD). However, the factors associated with NAFLD in persons l...

Apr 06, 2020

In ENSURE-AF (NCT02072434), the oral Factor Xa inhibitor edoxaban showed similar efficacy and safety vs enoxaparin-warfarin in patients undergoing electrical cardioversion of nonvalvular atrial fibril...

Apr 06, 2020

Prasugrel was approved at a lower dose in 2014 in Japan than in the West because East Asian patients are considered more susceptible to bleeding than Western patients. However, real-world outcomes wit...

Apr 06, 2020

Occlusive atherosclerotic disease of the anterior cerebral circulation is one of the most common causes of anterior circulation ischemia and stroke. Treatment options include medical therapies (includ...

Apr 06, 2020

The early recognition of invasive bacterial infections (IBI) in children can be difficult. Clinically it is often challenging to differentiate between the early stages of an IBI and a benign self-limi...

Apr 06, 2020

Ceftobiprole is a new therapeutic option for bacterial pneumonia, with activity against most antimicrobial resistant gram-positive cocci, including methicillin-resistant Staphylococcus aureus. Data on...

Apr 06, 2020

The decision to perform a total knee arthroplasty (TKA) on a previously infected knee is made complicated by the higher risk for both a periprosthetic joint infection (PJI) and early failure. There is...

Apr 06, 2020

We review a series of isolated septic facet joints (ISFJ) that present as a distinct clinical entity compared with spondylodiscitis. We aim to raise awareness that septic facet joints are not a rare e...

Apr 06, 2020

To study the epidemiology of hospitalized serious infections in people with gout.We identified people with gout hospitalized with a primary diagnosis of pneumonia, sepsis/bacteremia, urinary tract inf...

Apr 06, 2020

Determine the frequency of polytraumatized pediatric patients involved in motorcycle accidents treated at the Pediatric Hospital of Sinaloa between 2015 and 2017, as well as to determine the frequency...

Apr 06, 2020

Dipeptidyl peptidase-4 inhibitors (or gliptins), a class of antidiabetic drugs, have recently been shown to have protective actions in the central nervous system. Their cellular and molecular mechanis...