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Critical Care General

Incident Comorbidities, Aging and the Risk of Stroke in 608,108 Patients with Atrial Fibrillation: A Nationwide Analysis.

May 01, 2020

We hypothesized that the change in stroke risk profile between baseline and follow-up may be a better predictor of ischemic stroke than the baseline stroke risk determination using the CHADS-VASc scor...

Comparison of longitudinal change in sST2 vs BNP to predict major adverse cardiovascular events in asymptomatic patients in the community.

May 01, 2020

Biomarker-based preventative and monitoring strategies are increasingly used for risk stratification in cardiovascular (CV) disease. The aim of this study was to investigate the utility of longitudina...

Prevalence and Associated Risk Factors of Sepsis among Neonates Admitted into Neonatal Intensive Care Units of Public Hospitals in Dhaka.

May 01, 2020

To determine the prevalence and associated risk factors of sepsis among neonates admitted into neonatal intensive care units (NICU) of public hospitals in Dhaka.This was a cross-sectional study conduc...

Two Cases of Influenza B Virus-Related Fatal Fulminant Pneumonia Complicated With Infection in China Diagnosed Using Next-Generation Sequencing (2018).

May 01, 2020

Two rare cases of Chinese female patients with influenza B virus infection complicated with both fulminant pneumonia and septicemia caused by Panton-Valentine leukocidin(PVL) positive methicillin-sens...

Rapidly expanding saphenous vein graft myoctic aneurysm causing ST-elevation myocardial infarction: a case report.

May 01, 2020

Mycotic aneurysms of coronary vein grafts are rare and associated with high mortality. They are most commonly a result of surgical or percutaneous intervention, and present with complications includin...

Impact of prehospital antibiotic therapy on septic shock mortality.

May 01, 2020

Septic shock (SS) is associated with high morbidity and mortality rate. Early antibiotic therapy administration in septic patients was shown to reduce mortality but its impact on mortality in a preho...

Frequency and management of maternal infection in health facilities in 52 countries (GLOSS): a 1-week inception cohort study.

May 01, 2020

Maternal infections are an important cause of maternal mortality and severe maternal morbidity. We report the main findings of the WHO Global Maternal Sepsis Study, which aimed to assess the frequency...

Characteristics of Schools with Youth Sports Concussion-Related Educational Policies and Practices.

May 01, 2020

School policies and practices designed to educate athletes, parents, and coaches about youth sports concussions may be a way to reduce concussion risk and improve both the recognition and management o...

Functional Neuroimaging in Psychiatry-Aiding in Diagnosis and Guiding Treatment. What the American Psychiatric Association Does Not Know.

May 01, 2020

While early efforts in psychiatry were focused on uncovering the neurobiological basis of psychiatric symptoms, they made little progress due to limited ability to observe the living brain. Today, we ...

Predicting Concussion Outcome by Integrating Finite Element Modeling and Network Analysis.

May 01, 2020

Concussion is a significant public health problem affecting 1.6-2.4 million Americans annually. An alternative to reducing the burden of concussion is to reduce its incidence with improved protective ...

Immunization with neural-derived peptides increases neurogenesis in rats with chronic spinal cord injury.

May 01, 2020

Immunization with neural-derived peptides (INDP) has demonstrated to be a promising therapy to achieve a regenerative effect in the chronic phase of the spinal cord injury (SCI). Nevertheless, INDP-in...

Does the skull Hounsfield unit predict shunt dependent hydrocephalus after decompressive craniectomy for traumatic acute subdural hematoma?

May 01, 2020

Posttraumatic hydrocephalus affects 11.9%-36% of patients undergoing decompressive craniectomy (DC) after traumatic brain injury and necessitates a ventriculo-peritoneal shunt placement. As bone and a...

The prevalence and importance of frailty in heart failure with reduced ejection fraction - an analysis of PARADIGM-HF and ATMOSPHERE.

May 01, 2020

Frailty, characterized by loss of homeostatic reserves and increased vulnerability to physiological decompensation, results from an aggregation of insults across multiple organ systems. Frailty can be...

Management of low blood pressure in ambulatory heart failure with reduced ejection fraction patients.

May 01, 2020

Low blood pressure is common in patients with heart failure and reduced ejection fraction (HFrEF). While spontaneous hypotension predicts risk in HFrEF, there is only limited evidence regarding the re...

Folic acid affects cardiometabolic, oxidative stress and immunohistochemical parameters in monocrotaline-induced rat heart failure.

May 01, 2020

Heart failure (HF) is one of the major cardiovascular causes of death worldwide. In this study, we explored the effects of folic acid (FA) on cardiometabolic, oxidative stress-biomarker changes and th...

Empagliflozin improves left ventricular diastolic function of db/db mice.

May 01, 2020

Investigation of the effect of SGLT2-inhibition by empagliflozin on left ventricular function in a model of diabetic cardiomyopathy.SGLT2 inhibition is a new strategy to treat diabetes. In the EMPAREG...

Delay optimization of multipoint pacing increases the cardiac index and narrows the QRS width.

May 01, 2020

The benefits of MPP delay optimization on hemodynamics and ventricular contraction synchronicity can be quantified with cardiac index (CI) and QRS width. A delay with the maximum CI and minimum QRS wi...

Longitudinal Competence Programs for Basic Point of Care Ultrasound in Critical Care.

May 01, 2020

Competence in Point-of-Care Ultrasound (PoCUS) is widely recommended by several critical care societies. Despite numerous introductory short-courses, very few doctors attain PoCUS competence, due to t...

Acute and long-term results of bipolar radiofrequency catheter ablation of refractory ventricular arrhythmias of deep intramural origin.

May 01, 2020

Successful bipolar radiofrequency catheter ablation (RFCA) of refractory ventricular arrhythmias (VAs) has been reported. However, the efficacy, safety, and long-term outcomes of bipolar RFCA of VAs a...

Ganoderic acid A alleviates myocardial ischemia-reperfusion injury in rats by regulating JAK2/STAT3/NF-κB pathway.

May 01, 2020

This study aimed to investigate the protective effect of GanodericacidA (GA) on myocardial ischemia-reperfusion (MIR) injury. The myocardial injury model in rats was established by ligating left anter...

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