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Critical Care General

Does Performance of D-Dimer for Diagnosis of Periprosthetic Joint Infection Change with the Virulence of Infecting Organism?

May 22, 2023

The impact of the organism virulence on diagnostic accuracy of D-Dimer for periprosthetic joint infection (PJI) is unknown. Our objective was to assess if the performance of D-Dimer in PJI diagnosis c...

Analysis of risk factors for parenteral nutrition-associated cholestasis in preterm infants: a multicenter observational study.

May 22, 2023

It is proposed that the development of parenteral nutrition-associated cholestasis (PNAC) was significantly associated with preterm birth, low birth weight, infection, etc.; however, the etiology and ...

The American Congress of Rehabilitation Medicine Diagnostic Criteria for Mild Traumatic Brain Injury.

May 22, 2023

To develop new diagnostic criteria for mild traumatic brain injury (TBI) that are appropriate for use across the lifespan and in sports, civilian trauma, and military settings.Rapid evidence reviews o...

Scoping Review on Educational Programs for Medical Professionals on the Management of Acute Agitation.

May 22, 2023

Agitation is a common reason for psychiatric consultation in the general hospital. The CL psychiatrist is often tasked with teaching the medical team how to manage agitation.The purpose of this scopin...

Effect of sevoflurane-remifentanil and propofol-remifentanil anesthesia on glycocalyx shedding during deep inferior epigastric perforator flap breast reconstruction: a prospective randomized, controlled trial.

May 15, 2023

The endothelial glycocalyx (EG) is an important structure that regulates vascular homeostasis. Deep inferior epigastric perforator (DIEP) flap is expected to cause substantial EG breakdown owing to th...

RP58 knockdown contributes to hypoxia-ischemia-induced pineal dysfunction and circadian rhythm disruption in neonatal rats.

May 15, 2023

Hypoxia-ischemia (HI) of the brain not only impairs neurodevelopment but also causes pineal gland dysfunction, which leads to circadian rhythm disruption. However, the underlying mechanism of circadia...

Early Surgical Stabilization of Rib Fractures is Feasible in Patients With Non-Urgent Operative Pelvic Injuries.

May 15, 2023

The feasibility of prioritizing surgical stabilization of rib fractures (SSRF) in patients with other injuries is unknown. The purpose of this study was to evaluate the timing and outcomes of SSRF bet...

Comparison of postoperative outcomes of TURP, laser vaporization and laser enucleation: A Double Propensity Score Matched Analysis.

May 15, 2023

To compare postoperative outcomes of three types of endourologic surgeries (TURP, laser vaporization (LVP) and laser enucleation (LEP)) for BPH treatment using the ACS-NSQIP database.The ACS-NSQIP dat...

An experimental porcine model of invasive candidiasis.

May 15, 2023

Invasive candidiasis (IC) is a severe and often fatal fungal infection that affects critically ill patients. The development of animal models that mimic human disease is essential for advancing our un...

Longitudinal assessment of cardiac parameters through MRI in breast cancer patients treated with anti-HER2 therapy.

May 15, 2023

We evaluated the early changes in left ventricular (LV) volumetric, functional, and tissue characteristics in human epidermal growth factor receptor 2 (HER2)-positive breast cancer patients treated wi...

Experiences of dignity: Age at onset of serious illness matters.

May 15, 2023

Preserving persons' dignity is integral to nursing. More research is needed to explore how a diversity of patients, particularly those that experience illness from a young age, experience dignity.Desc...

Saudi Critical Care Society clinical practice guidelines on the prevention of venous thromboembolism in adults with trauma: reviewed for evidence-based integrity and endorsed by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine.

May 15, 2023

To develop evidence-based clinical practice guidelines on venous thromboembolism (VTE) prevention in adults with trauma in inpatient settings.The Saudi Critical Care Society (SCCS) sponsored guideline...

Necrotizing fasciitis of the chest wall caused by empyema necessitans following tuberculosis: Case report and literature review.

May 08, 2023

Empyema is a serious complication characterized by pus and bacteria in the pleural space which may progress to necrosis, cavitation, or fistulas in the thoracic cavity. Infection and trauma are the co...

Successful use of subcutaneous anakinra in hemophagocytic lymphohistiocytosis precipitated by candidiasis in a patient with systemic lupus erythematosus: A case report and description of a novel therapeutic regimen.

May 08, 2023

Hemophagocytic lymphohistiocytosis (HLH) is a rare and often fatal condition characterized by inappropriate immune system activation leading to a "cytokine storm", and ultimately resulting in end-orga...

AT 1 inhibition mediated neuroprotection after experimental traumatic brain injury is dependent on neutrophils in male mice.

May 08, 2023

After traumatic brain injury (TBI) cerebral inflammation with invasion of neutrophils and lymphocytes is a crucial factor in the process of secondary brain damage. In TBI the intrinsic renin-angiotens...

Emulating target trials comparing early and delayed intubation strategies.

May 08, 2023

Whether intubation should be initiated early in the clinical course of critically ill patients remains a matter of debate. Results from prior observational studies are difficult to interpret because o...

Assessing Decision-Making Algorithm for Collecting Blood Culture in the ICU

May 05, 2023

The following is a summary of “Assessing a standardized decision-making algorithm for blood culture collection in the intensive care unit,” published in the February 2023 issue of Critical Care by...

Interpretable and Accurate Prediction of ICU-acquired AKI

May 04, 2023

The following is a summary of "Accurate and interpretable prediction of ICU-acquired AKI ," published in the February 2023 issue of Critical Care by Schwager et al. Two parsimonious algorithms ...

Revolutionizing ARDS Detection: The Power of Reverse-Triggering Neural Networks

May 03, 2023

The following is a summary of “Reverse triggering neural network and rules-based automated detection in acute respiratory distress syndrome,” published in the January 2023 issue of  Critical Care...

PEEP in COVID-19 Patients: A Retrospective Study on RV Dysfunction

May 01, 2023

The following is a summary of "Optimal positive end-expiratory pressure reduces right ventricular dysfunction in COVID-19 patients on venovenous extracorporeal membrane oxygenation: A retrospective si...

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