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Critical Care General

Prognostic value of plasma mitochondrial DNA in acute respiratory distress syndrome (ARDS): a single-center observational study.

May 19, 2020

Mitochondrial DNA (mtDNA) has been reported to play a critical role in the progression of systemic inflammatory response syndrome (SIRS). The pathophysiology of acute respiratory distress syndrome (AR...

Up-regulated CCL2 promotes ischemic stroke via chemokine signaling pathway.

May 19, 2020

This study aims to evaluate the potential effect and the underlying mechanism of CCL2 in ischemic stroke.An integrated bioinformatics analysis was performed to identify the differentially expressed (D...

An Updated Systematic Review and Meta-Analysis of Results of Transcervical Carotid Artery Stenting with Flow Reversal.

May 19, 2020

Transcervical carotid artery stenting (CAS) has emerged as an alternative to transfemoral CAS. An earlier systematic review from our group (n = 12 studies; 739 transcervical CAS procedures [489/739 wi...

Isovaleroylbinankadsurin A ameliorates cardiac ischemia/reperfusion injury through activating GR dependent RISK signaling.

May 19, 2020

Ischemia/reperfusion (I/R) injury is a pathological process caused by reperfusion. The prevention of I/R injury is of great importance as it would enhance the efficacy of myocardial infarction treatme...

A directed network analysis of the cardiome identifies molecular pathways contributing to the development of HFpEF.

May 19, 2020

The metabolic syndrome and associated comorbidities, like diabetes, hypertension and obesity, have been implicated in the development of heart failure with preserved ejection fraction (HFpEF). The mol...

Demographic Characteristics Among Patients With Chronic Exertional Compartment Syndrome of the Lower Leg.

May 19, 2020

Clinical Scenario: Chronic exertional compartment syndrome (CECS) is a condition related with ischemia of the body's tissue due to increases in intracompartmental pressures, which involves, among othe...

Severe obesity is associated with higher in-hospital mortality in a cohort of patients with COVID-19 in the Bronx, New York.

May 19, 2020

New York is the current epicenter of Coronavirus disease 2019 (COVID-19) pandemic. The underrepresented minorities, where the prevalence of obesity is higher, appear to be affected disproportionately....

Validating the APPROACH CVICU Readmission Score

May 16, 2020

Published reports indicate that as many as 8% of cardiac surgical patients are readmitted to a cardiovascular intensive care unit (CVICU) during the same hospital stay, with readmission associated wit...

Developing ICU Recovery Centers

May 14, 2020

Data indicate that more than 6 million people will become critically ill each year, and of these patients, an increasing number will survive due to advances in critical care. These treatments, however...

Immune responses to stroke: mechanisms, modulation, and therapeutic potential.

May 12, 2020

Stroke is the second leading cause of death worldwide and a leading cause of disability. Most strokes are caused by occlusion of a major cerebral artery, and substantial advances have been made in elu...

Hydrogel-based zinc ion sensor on optical fiber with high resolution and application to neural cells.

May 12, 2020

Solid-state zinc ion sensor is developed with high enough resolution and reproducibility for the potential application in brain injury monitoring. An optical diffuser is incorporated into the zinc ion...

Post-stroke infections associated with spleen volume reduction: A pilot study.

May 12, 2020

Spleen volume reduction followed by re-expansion has been described in acute ischemic stroke in both animal and human studies. Splenic contraction might be partially due to sympathetic hyperactivity a...

Association between body mass index and stroke severity in acute ischemic stroke with non-valvular atrial fibrillation.

May 12, 2020

The objective of this study was to investigate the association between body mass index (BMI) and both initial stroke severity at presentation and functional outcomes after acute ischemic stroke (AIS) ...

The Frequency of the Minor Polymorphisms in the , Genes, and Clinical Outcomes in Russian and Buryat Patients with Acute Coronary Syndrome.

May 12, 2020

To determine the differences in the frequencies of polymorphic variants at the rs4244285(*2), rs4986893 (*3), rs12248560 (*17), loci of the gene, and the rs2305948 locus of the gene in patients rec...

Argatroban Treatment and Decreased Fibrinogen in a Septic Patient.

May 12, 2020

Disseminated intravascular coagulation (DIC) is a consumptive coagulopathy associated with multiple conditions. Diagnosis is based upon clinical and laboratory findings with assessment of fibrinogen,...

A signal cascade amplification strategy based on RT-PCR triggering of a G-quadruplex DNAzyme for a novel electrochemical detection of viable Cronobacter sakazakii.

May 12, 2020

Cronobacter sakazakii is an important opportunistic food-borne pathogen, and it can cause severe diseases with main symptoms including neonatal meningitis, necrotizing enterocolitis, and sepsis. For t...

Operative Surgery Is Rarely Required in the Acute Management of Diverticulitis in the Modern Era.

May 12, 2020

Acute diverticulitis is an emergency surgical condition that is commonly managed an acute surgical unit model. Operative surgery is indicated in selected situations including generalized peritonitis ...

[CT imaging features of patients with different clinical types of COVID-19].

May 12, 2020

To investigate the CT findings of patients with different clinical types of coronavirus disease 2019 (COVID-19).A total of 67 patients diagnosed as COVID-19 by nucleic acid testing were collected and ...

CT Scans Obtained for Nonpulmonary Indications: Associated Respiratory Findings of COVID-19.

May 12, 2020

Background Atypical manifestations of COVID-19 are being encountered as the pandemic unfolds, leading to non-chest CT scans that may uncover unsuspected pulmonary disease. Purpose To investigate patie...

[The e-cigarette: the ultimate Trojan horse].

May 12, 2020

Electronic cigarettes have rapidly attracted interest as a method to help people quit smoking, on the premise that e-cigarettes are less harmful than tobacco. However, so far studies have not provided...

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