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Critical Care General

miR-532-3p-CSF2RA Axis as a Key Regulator of Vulnerable Atherosclerotic Plaque Formation.

Jun 01, 2020

The most dangerous atherosclerotic plaques, referred to as "vulnerable," are most likely to trigger acute atherothrombotic events such as myocardial infarction (heart attack) and stroke. Our goal was ...

The effects of body mass index on outcomes for patients undergoing surgical aortic valve replacement.

Jun 01, 2020

Most of the studies of obesity and postoperative outcome have looked predominantly at coronary artery bypass grafting with fewer focused on valvular disease. The purpose of this study was to compare t...

Prognostic accuracy of SIRS criteria and qSOFA score for in-hospital mortality among influenza patients in the emergency department.

Jun 01, 2020

The seasonal influenza epidemic is an important public health issue worldwide. Early predictive identification of patients with potentially worse outcome is important in the emergency department (ED)....

Whole blood transcriptomic investigation identifies long non-coding RNAs as regulators in sepsis.

Jun 01, 2020

Sepsis is a fatal disease referring to the presence of a known or strongly suspected infection coupled with systemic and uncontrolled immune activation causing multiple organ failure. However, curren...

Effectiveness of the Brains Ahead! Intervention: 6 Months Results of a Randomized Controlled Trial in School-Aged Children With Mild Traumatic Brain Injury.

Jun 01, 2020

To examine the effectiveness of Brains Ahead!, a psychoeducational intervention aimed to prevent long-term problems with activities and participation in children after mild traumatic brain injury (mTB...

Activities and Participation in the First 6 Months After Mild Traumatic Brain Injury in Children and Adolescents.

Jun 01, 2020

To investigate the natural course of activities and participation of children up to 6 months after a mild traumatic brain injury (mTBI).A prospective longitudinal cohort study with complete data sets ...

How Repetitive Traumatic Injury Alters Long-Term Brain Function.

Jun 01, 2020

How recurrent traumatic brain injury (rTBI) alters brain function years after insult is largely unknown. This study aims to characterize the mechanistic cause for long-term brain deterioration followi...

nAnnexin A1 is a Potential Novel Biomarker of Congestion in Acute Heart Failure.

Jun 01, 2020

The study sought to identify the role of Annexin A1 as a congestion marker in acute heart failure, and to identify its putative role in predicting clinical outcomes.Annexin A1 (AnxA1) is a protein tha...

Wearable Patch Based Estimation of Oxygen Uptake and Assessment of Clinical Status during Cardiopulmonary Exercise Testing in Patients with Heart Failure.

Jun 01, 2020

To estimate oxygen uptake (VO) from cardiopulmonary exercise testing (CPX) using simultaneously recorded seismocardiogram (SCG) and electrocardiogram (ECG) signals captured with a small wearable patch...

Aortic Insufficiency during HeartMate 3 Left Ventricular Assist Device Support: AI in HeartMate 3.

Jun 01, 2020

Aortic insufficiency (AI) is associated with morbidity and mortality in patients with continuous-flow left ventricular assist devices (LVADs), whereas its impact on the HeartMate 3 LVAD cohorts remain...

A single center retrospective cohort study evaluating use of direct oral anticoagulants (DOACs) in morbidly obese veteran population.

Jun 01, 2020

Direct oral anticoagulants (DOACs) are preferred over warfarin for the treatment of venous thromboembolism (VTE) as well as atrial fibrillation (AF). The efficacy and safety of fixed dose regimen of D...

Fenestrated Repair Improves Perioperative Outcomes but Lacks a Hospital Volume Association for Complex Abdominal Aortic Aneurysms.

Jun 01, 2020

Complex abdominal aortic aneurysms (cAAAs) have traditionally been treated with an open surgical repair (OSR). Over the past decade, fenestrated endovascular graft repair (FEVAR) has emerged as a viab...

Follow-Up Care & Post-Stroke Readmission

May 28, 2020

Research indicates that more than 750,000 patients per year are hospitalized for stroke in the US, with 50% experiencing lasting effects. Among stroke survivors, 5% to 14% experience another stroke in...

Subcapsular Renal Hematoma in Simultaneous Pancreas Kidney Transplantation.

May 28, 2020

Subcapsular renal hematoma (SRH) is a challenging condition, which may jeopardize kidney function or constitute a life-threatening event. This is particularly true in single-kidney patients, such as k...

Transperineal free-hand mpMRI fusion targeted biopsies under local anesthesia for Prostate Cancer Diagnosis: a multicenter prospective study of 1,014 cases.

May 28, 2020

No large multicentre prospective studies ever addressed the outcomes of mpMRI targeted fusion transperineal biopsy (TPFBx) under local anesthesia (LA). The debate upon best biopsy modality is still op...

Potential therapeutic effect of Qingwen Baidu Decoction against Corona Virus Disease 2019: a mini review.

May 28, 2020

The Corona Virus Disease 2019 (COVID-19) is an acute respiratory infectious disease. At present, COVID-19 has no specific therapeutic drugs, and the main clinical treatment is symptomatic treatment an...

Acute Esophageal Necrosis in a Septic Patient with a History of Cardiovascular Disease.

May 28, 2020

Acute esophageal necrosis (AEN), or colloquially named "black esophagus," is a rare clinical condition often associated with ischemic injury to the esophagus secondary to splanchnic vasoconstriction d...

Subcutaneous Selatogrel Inhibits Platelet Aggregation in Patients With Acute Myocardial Infarction.

May 28, 2020

Oral P2Y receptor antagonists exhibit delayed onset of platelet inhibition in patients with acute myocardial infarction (AMI). Selatogrel is a potent, highly selective, and reversible P2Y receptor ant...

Apixaban versus No Anticoagulation in Patients Undergoing Long-Term Dialysis with Incident Atrial Fibrillation.

May 28, 2020

The relative efficacy and safety of apixaban compared with no anticoagulation have not been studied in patients on maintenance dialysis with atrial fibrillation. We aimed to determine whether apixaban...

OUTCOMES AND STRATEGY OF TAILORED ANTIPLATELET THERAPY WITH TICAGRELOR IN PATIENTS UNDERGOING TRANSCAROTID ARTERY REVASCULARIZATION (TCAR).

May 28, 2020

Antiplatelet drug resistance is associated with periprocedural ischemic complications in patients undergoing intravascular stent implantation. Nonresponders are subject to increased risk of stent thro...

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