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Critical Care General

Sodium-glucose cotransporter 2 inhibitors represent a paradigm shift in the prevention of heart failure in type 2 diabetes patients.

Jun 22, 2020

Recent major clinical trials of the use of sodium-glucose cotransporter 2 (SGLT2) inhibitors in patients with type 2 diabetes have shown that they reduce three-point major adverse cardiovascular event...

Use of in vitro assays to identify antibiotics that are cytotoxic to normal equine chondrocytes and synovial cells.

Jun 18, 2020

Intra-articular (IA) antibiotic usage is prevalent in equine practice. However, recent emergence of antimicrobial resistance prompts re-evaluation of antibiotic selection, particularly when used proph...

Analysis of 2019 novel coronavirus infection and clinical characteristics of outpatients: An epidemiological study from a fever clinic in Wuhan, China.

Jun 18, 2020

Since the outbreak of 2019 novel coronavirus (SARS-CoV-2) pneumonia, thousands of patients with fever or cough were flocked into fever clinic of designated hospitals in Wuhan, China. To date, no data ...

Alterations of the oral microbiome and cumulative carbapenem exposure are associated with Stenotrophomonas maltophilia infection in patients with acute myeloid leukemia receiving chemotherapy.

Jun 18, 2020

Stenotrophomonas maltophilia is increasingly common in patients with acute myeloid leukemia (AML). Relatively little is known about factors that drive S. maltophilia infection. We evaluated the utilit...

Mechanical Ventilation in Pregnancy Due to COVID-19: A Cohort of Three Cases.

Jun 18, 2020

We describe our experience with three pregnant women with novel coronavirus disease 2019 (COVID-19) who required mechanical ventilation. Recent data suggest a mortality of 88% in nonpregnant patients ...

Protamine Use in Transfemoral Carotid Artery Stenting is Not Associated with an Increased Risk of Thromboembolic Events.

Jun 18, 2020

Protamine use in carotid endarterectomy has been shown to be associated with fewer perioperative bleeding complications without higher rates of thromboembolic events. However, the effect of protamine ...

Effect of Low Diastolic Blood Pressure to Cardiovascular Risk in Patients With Ischemic Stroke or Transient Ischemic Attacks Under Different Systolic Blood Pressure Levels.

Jun 18, 2020

In the context of recently updated strategies of pressure management, there is a paucity of evidence on the effect of diastolic blood pressure (DBP) level on adverse events among stroke patients. Thi...

Chemotactic invasion in deep soft tissue by is essential for the progression of necrotic lesions.

Jun 18, 2020

Necrotizing soft tissue infections (NSTI) progress to severe necrosis and result in fatal sepsis within a short time. is a causative agent and can spread from the initial infection site through soft ...

Genomic characterization of multi-drug resistant ESBL-producing Escherichia coli ST58 causing fatal colibacillosis in critically endangered Brazilian merganser (Mergus octosetaceus).

Jun 18, 2020

Even though antimicrobial-resistant bacteria have begun to be detected in wildlife, raising important issues related to their transmission and persistence of clinically important pathogens in the envi...

Mimicry of surgical site infection - Case report.

Jun 18, 2020

Calciphylaxis is a rare complication of secondary hyperparathyroidism caused by calcifications of small blood vessels in the skin and soft tissue. The disease occurs almost exclusively in patients wit...

Separate N-acetyl aspartyl glutamate, N-acetyl aspartate, aspartate, and glutamate quantification after pediatric mild traumatic brain injury in the acute phase.

Jun 18, 2020

To separately measure N-acetyl aspartul glutamate (NAAG), N-acetyl aspartate (NAA), aspartate (Asp), and glutamate (Glu) concentrations in white matter (WM) using J-editing techniques in patients with...

Data mining to understand how health status preceding traumatic brain injury affects functional outcome: A population-based sex-stratified study.

Jun 18, 2020

To understand how health status preceding traumatic brain injury (TBI) affects relative functional gain after inpatient rehabilitation using a data mining approach.Population-based, sex-stratified, re...

Clinical presentation and 3-year outcomes of patients with acute coronary syndromes and non-obstructive coronary arteries on angiography.

Jun 18, 2020

With the emerging interest in patients with myocardial infarction with non-obstructive coronary arteries (MINOCA), there is a need to define an even broader group of patients with the syndrome of myoc...

Adjustment of Stent Retriever Length to Clot Extent Affects First-Pass Reperfusion in Endovascular Treatment of Acute Ischemic Stroke.

Jun 18, 2020

Stent retriever technology has evolved, and significantly longer devices have become available for mechanical thrombectomy (MT) of large cerebral vessel occlusions in ischemic stroke. We hypothesized ...

Diffusion-Weighted Imaging-Fluid-Attenuated Inversion Recovery Mismatch Is Associated with 90-Day Functional Outcomes in Patients Undergoing Mechanical Thrombectomy.

Jun 18, 2020

Diffusion-weighted imaging-fluid-attenuated inversion recovery (DWI-FLAIR) mismatch is an early sign of acute ischemic stroke. DWI-FLAIR mismatch was reported to be valuable to select patients with un...

Luteolin alleviates myocardial ischemia reperfusion injury in rats via Siti1/NLRP3/NF-κB pathway.

Jun 18, 2020

The purpose of this study was to investigate the effects of luteolin (Lu) on myocardial ischemia-reperfusion (I/R) injury in rats. I/R model was established by ligating left anterior descending branch...

Clinical and radiological risk factors of autograft cranioplasty resorption after decompressive craniectomy for traumatic brain injury.

Jun 18, 2020

The repositioning of an autologous bone flap after decompressive craniectomy (DC) for traumatic intracranial hypertension remains the first-line treatment for cranial reconstruction. Aseptic autologou...

Sestrin 2 controls the cardiovascular aging process via an integrated network of signaling pathways.

Jun 18, 2020

As an inevitable biological process, cardiovascular aging is the greatest risk factor for cardiovascular diseases (CVDs). Sestrin 2 (Sesn2), a stress-inducible and age-related protein associated with ...

Prognosis and Natural History of Conduction System Disease in Patients Undergoing Coronary Angiography.

Jun 18, 2020

Infranodal conduction abnormalities, including right or left bundle branch block bifascicular block, and nonspecific intraventricular conduction block are common electrocardiogram (ECG) abnormalities ...

Spectrum of common and uncommon causes of knee joint hyaline cartilage degeneration and their key imaging features.

Jun 15, 2020

Hyaline cartilage lining the surfaces of diarthrodial joints is an important construct for transmission of load and to reduce friction between the bones. Normal wear and tear accounts for about 3-5 pe...

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