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Critical Care General

Insulin therapy and blood glucose management in critically ill patients: a 1-day cross-sectional observational study in 69 French intensive care units.

Jun 19, 2023

Hyperglycaemia is common in critically ill patients, but blood glucose and insulin management may differ widely among intensive care units (ICUs). We aimed to describe insulin use practices and the re...

Impact of transfer to reference centres and surgical timing on the prognosis of surgically treated patients with infective endocarditis: a prospective multicenter cohort study.

Jun 12, 2023

To compare outcomes of patients with infective endocarditis (IE) first treated in secondary hospitals and then transferred to reference centres for surgery, to those diagnosed in reference centres, an...

Comparison of endotracheal aspirate and bronchoalveolar lavage fluid metagenomic next-generation sequencing in severe pneumonia: a nested, matched case-control study.

Jun 12, 2023

To compare clinical outcomes in patients with severe pneumonia according to the diagnostic strategy used.In this retrospective, nested, case-control study, patients with severe pneumonia who had under...

Late diagnosis of congenital diaphragmatic hernia: a case report.

Jun 12, 2023

Congenital diaphragmatic hernia beyond the neonatal period is not uncommon. Its diagnosis in infancy and early childhood poses a challenge owing to different clinical presentation ranging from gastroi...

Comparison of Veno-arterial Extracorporeal Membrane Oxygenation Configurations for Patients Listed for Heart Transplantation.

Jun 05, 2023

Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) as a bridge to eventual heart transplantation (HT) is increasingly used worldwide. However, the effect of different VA-ECMO types on HT outc...

Identification of proteins regulated by chlorogenic acid in an ischemic animal model: a proteomic approach.

Jun 05, 2023

Cerebral ischemia is a serious neurological disorder that can lead to high morbidity and mortality. Chlorogenic acid is a polyphenol compound with antioxidant that can regulate proteins in cerebral is...

Outcomes Following Hemiarthroplasty for Femoral Neck Fracture in Patients with Hemiparesis.

Jun 05, 2023

Hemiparesis increases the risk of femoral neck fracture (FNF) in the elderly, which frequently necessitates hemiarthroplasty. There are limited reports on the outcomes of hemiarthroplasty in patients ...

ICP, PRx, CPP, and ∆CPPopt in pediatric traumatic brain injury: the combined effect of insult intensity and duration on outcome.

Jun 05, 2023

The aim was to investigate the combined effect of insult intensity and duration, regarding intracranial pressure (ICP), pressure reactivity index (PRx), cerebral perfusion pressure (CPP), and optimal ...

Effect of voluntary exercise on endogenous pain control systems and post-traumatic headache in mice.

Jun 05, 2023

Traumatic brain injury (TBI) can cause acute and chronic pain along with motor, cognitive and emotional problems. Although the mechanisms are poorly understood, previous studies suggest disruptions in...

High-intensity interval training versus moderate-intensity continuous training in patients with heart failure: a systematic review and meta-analysis.

Jun 05, 2023

The effects of high-intensity interval training (HIIT) in patients with heart failure (HF) remain controversial. This systematic review and meta-analysis aimed to examine the efficacy of HIIT versus m...

Association of diabetic retinopathy with risk of developing cardiovascular diseases in patients undergoing hemodialysis: A population-based cohort study.

May 29, 2023

While patients undergoing dialysis have substantially increased cardiovascular event rates compared with the general population, predicting individual risk remains difficult. Whether diabetic retinopa...

Nucleated Red Blood Cells Are Predictive of In-Hospital Mortality for Pediatric Patients.

May 29, 2023

We sought to establish whether nucleated red blood cells (NRBCs) are predictive of disposition, morbidity, and mortality for pediatric patients presenting to the emergency department (ED).A single-cen...

Clinical characteristics of hospitalized children with community-acquired pneumonia and respiratory infections: Using machine learning approaches to support pathogen prediction at admission.

May 29, 2023

Acute respiratory infections (ARIs) are common in children. We developed machine learning models to predict pediatric ARI pathogens at admission.We included hospitalized children with respiratory infe...

E. faecalis sepsis and Asherman's syndrome as complications of Sonata System transcervical fibroid ablation.

May 29, 2023

The Sonata System is a minimally-invasive, ultrasound-guided transcervical fibroid ablation procedure for management of symptomatic uterine fibroids. Since its approval by the U.S Food and Drug Admini...

Annual trends of cystectomy complications: A contemporary analysis of the NSQIP database.

May 29, 2023

Despite significant morbidity, radical cystectomy (RC) is standard of care for muscle invasive bladder cancer, certain high-risk nonmuscle invasive tumors and after failure of intravesical or trimodal...

Repeated mild traumatic brain injury in mice elicits long term innate immune cell alterations in blood, spleen, and brain.

May 29, 2023

Mild traumatic brain injury is an insidious event whereby the initial injury leads to ongoing secondary neuro- and systemic inflammation through various cellular pathways lasting days to months after ...

Temporal relationship between vasopressor and sedative administration and cerebrovascular response in traumatic brain injury: a time-series analysis.

May 29, 2023

Although vasopressor and sedative agents are commonly used within the intensive care unit to mediate systemic and cerebral physiology, the full impact such agents have on cerebrovascular reactivity re...

Simplifying Retroperitoneal Robotic Single-port Surgery: Novel Supine Anterior Retroperitoneal Access.

May 22, 2023

Multiport robotic surgery in the retroperitoneum is limited by the bulky robotic frame and clashing of instruments. Moreover, patients are placed in the lateral decubitus position, which has been link...

Multi-task learning with dynamic re-weighting to achieve fairness in healthcare predictive modeling.

May 22, 2023

The emphasis on fairness in predictive healthcare modeling has increased in popularity as an approach for overcoming biases in automated decision-making systems. The aim is to guarantee that sensitive...

Relationship between frailty and methotrexate discontinuation due to adverse events in rheumatoid arthritis patients.

May 22, 2023

Methotrexate (MTX) is an anchor drug in the treatment of rheumatoid arthritis (RA). Frailty is the intermediate condition between being healthy and disabled, and can lead to negative health outcomes. ...

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