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Critical Care General

Prehospital clinical signs are a poor predictor of raised intracranial pressure following traumatic brain injury.

Sep 21, 2020

For the prehospital diagnosis of raised intracranial pressure (ICP), clinicians are reliant on clinical signs such as the Glasgow Coma Score (GCS), pupillary response and/or Cushing's triad (hypertens...

Differential Regional Responses in Soluble Monomeric Alpha Synuclein Abundance Following Traumatic Brain Injury.

Sep 21, 2020

Alpha synuclein (α-synuclein) is a neuronal protein found predominately in presynaptic terminals. While the pathological effect of α-synuclein aggregates has been a topic of intense study in several...

Unmet rehabilitation needs indirectly influence life satisfaction 5 years after traumatic brain injury: A Veterans Affairs TBI Model Systems study.

Sep 21, 2020

Describe the association between unmet rehabilitation needs and life satisfaction five years after traumatic brain injury (TBI).Prospective observational cohort.Five Veterans Affairs (VA) Polytrauma R...

Silencing circ_0062389 alleviates cardiomyocyte apoptosis in heart failure rats via modulating TGF-β1/Smad3 signaling pathway.

Sep 21, 2020

CircRNA serves a crucial role in the development of heart failure (HF). Nevertheless, the regulatory mechanisms of circ_0062389 in HF are unknown. This study aims to examine the effect and mechanism o...

Association between reproductive lifespan and lung function among postmenopausal women.

Sep 21, 2020

Hye Yun Park, MD, PhD. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06...

Hospital attendance and admission trends for cardiac diseases during the COVID-19 outbreak and lockdown in Greece.

Sep 21, 2020

The coronavirus disease 2019 (COVID-19) outbreak, along with implementation of lockdown and strict public movement restrictions, in Greece has affected hospital visits and admissions. We aimed to inve...

Underuse of oral anticoagulants in privately insured patients with atrial fibrillation: A population being targeted by the IMplementation of a randomized controlled trial to imProve treatment with oral AntiCoagulanTs in patients with Atrial Fibrillation (IMPACT-AFib).

Sep 21, 2020

Many studies showing underuse of oral anticoagulants (OACs) in patients with atrial fibrillation (AF) predated the advent of the non-vitamin K antagonist OACs. We retrospectively examined use of OACs ...

Compound Dan Zhi tablet attenuates experimental ischemic stroke via inhibiting platelet activation and thrombus formation.

Sep 17, 2020

Compound Dan Zhi tablet (DZT) is a commonly used traditional Chinese medicine formula. It has been used for the treatment of ischemic stroke for many years in clinical. However, its pharmacological me...

Pediatric chest x-ray in covid-19 infection.

Sep 17, 2020

The outbreak of COVID-19 has become pandemic. Pediatric population has been less studied than adult population and prompt diagnosis is challenging due to asymptomatic or mild episodes. Radiology is an...

Adherence to study drug in a stroke prevention trial"?>.

Sep 17, 2020

Standards for reporting and analyzing adherence to medical therapy have recently improved due to international consensus efforts. If applied to clinical trial research in patients with stroke, these i...

Recent advances in developing biosensing based platforms for neonatal sepsis.

Sep 17, 2020

Neonatal sepsis is a bloodstream infection primarily caused by Escherichia coli (E. coli), Group B Streptococcus (GBS), Listeria monocytogenes, Haemophilus influenzae, S. aureus, Klebsiella spp. and n...

Multiplexed Plasma Immune Mediator Signatures Can Differentiate Sepsis From NonInfective SIRS: American Surgical Association 2020 Annual Meeting Paper.

Sep 17, 2020

Sepsis and sterile both release "danger signals' that induce the systemic inflammatory response syndrome (SIRS). So differentiating infection from SIRS can be challenging. Precision diagnostic assays ...

Helmet Usage Reduces Serious Head Injury Without Decreasing Concussion After Bicycle Riders Crash.

Sep 17, 2020

The importance of bicycle helmets in reducing injuries is unclear. Our center receives a disproportionate number of bicycle crash victims. We sought to evaluate the types of injuries observed and the ...

Whole Blood is Superior to Component Transfusion for Injured Children: A Propensity Matched Analysis.

Sep 17, 2020

To compare a propensity-matched cohort of injured children receiving conventional blood component transfusion to injured children receiving low-titer group O negative whole blood.Transfusion of whole ...

The effect of age and competition level on subtle motor performance in adolescents medically-cleared post-concussion: Preliminary findings.

Sep 17, 2020

To examine the effect of age and level of competition on subtle motor performance in adolescents who have recently been medically-cleared post-concussion (MC post-concussion) and never-injured control...

Clinical Course of COVID-19 Infection in Patients Urgently Operated of Cardiac Surgical Procedures.

Sep 17, 2020

The aim of this study was to describe the clinical course of a consecutive series of patients operated of urgent cardiac surgery during COVID-19 outbreak.In Italy, COVID outbreak has mostly occurred i...

Functional status mediates the association of nutritional status with depressive symptoms in patients with heart failure.

Sep 17, 2020

The decline of nutritional status and depressive symptoms are pandemic in heart failure patients and functional status may play a pivotal role between these. This study aimed to determine whether nutr...

The Extent of Late Gadolinium Enhancement Can Predict Adverse Cardiac Outcomes in Patients with Non-Ischemic Cardiomyopathy with Reduced Left Ventricular Ejection Fraction: A Prospective Observational Study.

Sep 17, 2020

The clinical course of an individual patient with heart failure is unpredictable with left ventricle ejection fraction (LVEF) only. We aimed to evaluate the prognostic value of cardiac magnetic resona...

The COVID-19 Pandemic's Impact on Critical Care Resources and Providers: A Global Survey.

Sep 17, 2020

The COVID-19 pandemic has severely impacted Intensive Care Units (ICUs) and Critical Care Healthcare Providers (HCPs) worldwide.How do regional differences and perceived lack of ICU resources affect c...

Persistent Racial and Sex Disparities in Outcomes After Coronary Artery Bypass Surgery: A Retrospective Clinical Registry Review in the Drug-eluting Stent Era.

Sep 17, 2020

The purpose of this study was to assess the temporal trends in 30-day mortality by race group for patients undergoing coronary artery bypass grafting (CABG) between 2011 and 2018 and to investigate th...

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