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Critical Care General

Recommended antimicrobial therapy for common inpatient infections: a comparative review of guidelines across 51 hospital trusts in England.

Oct 05, 2020

The number of different antimicrobial recommendations between hospital trusts for the same indication in England is unknown.We aimed to evaluate the heterogeneity of antimicrobial recommendations for ...

Variability in Serum Sodium Concentration and Prognostic Significance in Severe Traumatic Brain Injury: A Multicenter Observational Study.

Oct 05, 2020

Dysnatremia is common in severe traumatic brain injury (TBI) patients and may contribute to mortality. However, serum sodium variability has not been studied in TBI patients. We hypothesized that such...

Optical coherence tomography microscopy in experimental traumatic brain injury.

Oct 05, 2020

Worldwide elderly traumatic brain injury (TBI) patients tend to become an increasing burden to the society. Thus, a faster and less expensive way of evaluating TBI victims is needed. In the present st...

The Effect of Trauma Center Verification Level on Outcomes in TBI patients undergoing Inter-facility Transfer.

Oct 05, 2020

Previous literature demonstrates increased mortality for Traumatic Brain Injury (TBI) with transfer to a Level II versus Level I trauma center. Our objective is to determine the effect of the most rec...

Systolic Blood Pressure and Outcomes in Older Patients with HFpEF and Hypertension.

Oct 05, 2020

New hypertension and heart failure guidelines recommend that systolic blood pressure (SBP) in patients with heart failure with preserved ejection fraction (HFpEF) and hypertension be lowered to <13...

β-Blocker Use and Risk of Mortality in Heart Failure Patients Initiating Maintenance Dialysis.

Oct 05, 2020

β-blockers are recommended for heart failure (HF) patients but their benefit in the dialysis population is uncertain. β-blockers are heterogeneous including with respect to their removal by hemodial...

Tumor Embolism Through Right-to-Left Shunt Due to Venous Invasion of Esophageal Carcinoma.

Oct 05, 2020

A 69-year-old man was admitted to the hospital with right hemiparesis and global aphasia. Perfusion computed tomography imaging revealed ischemic penumbra in the middle cerebral artery territory. Angi...

Impact of coronavirus disease 2019 (COVID-19) outbreak on acute admissions at the emergency and cardiology departments across Europe.

Oct 05, 2020

We evaluated whether the severe acute respiratory syndrome coronavirus 2 pandemic was associated with changes in the pattern of acute cardiovascular admissions across European centres.We set-up a mult...

Internet search volume for chest pain during the COVID-19 pandemic.

Oct 05, 2020

During the COVID-19 pandemic there has been a reduction in hospital admissions for acute myocardial infarction. This manuscript presents the analysis of Google Trends meta-data and shows a marked spik...

Bilateral optic disc edema with preserved visual function not related to papilledema.

Oct 05, 2020

Bilateral optic disc edema (ODE) with preserved visual function is typically a result of papilledema, but the causes of this finding in the absence of raised intracranial pressure have not been system...

Flow Cytometry: An Important Diagnostic Tool in Critically Ill Preterm Neonates with Suspected Sepsis.

Oct 01, 2020

 Sepsis is a major cause of neonatal mortality. The gold standard for diagnosis is blood culture which suffers from low sensitivity and huge turn-around time. Flow cytometry has been extensively app...

Improving the performance of CNN to predict the likelihood of COVID-19 using chest X-ray images with preprocessing algorithms.

Oct 01, 2020

This study aims to develop and test a new computer-aided diagnosis (CAD) scheme of chest X-ray images to detect coronavirus (COVID-19) infected pneumonia.CAD scheme first applies two image preprocessi...

Patterns of Mechanical Thrombectomy for Stroke Before and After the 2015 Pivotal Trials and US National Guideline Update.

Oct 01, 2020

Positive pivotal trials followed by guideline endorsement can be a major driver of change in US national medical practice patterns. We therefore analyzed national trends in the use and outcomes of mec...

Comparison between thoracic ultrasonography and thoracic radiography for the detection of thoracic lesions in dairy calves using a two-stage Bayesian method.

Oct 01, 2020

Infectious bronchopneumonia is a lower respiratory tract disease with major economic consequences in dairy calves. Thoracic radiography (TR) and thoracic ultrasonography (TUS) are two imaging diagnost...

Impact of Continuation of Parenteral Nutrition on Outcomes of Patients with Blood Stream Infections.

Oct 01, 2020

The impact of continuing parenteral nutrition (PN) in patients who develop blood stream infections (BSI) while receiving PN is largely unknown. Adult patients admitted to a large academic center ove...

Trends in Costs and Risk Factors of 30-Day Readmissions for Transcatheter Aortic Valve Implantation.

Oct 01, 2020

As transcatheter aortic valve implantation (TAVI) continues its rapid growth as a treatment approach for aortic stenosis, costs associated with TAVI and its burden to healthcare systems will assume gr...

The impact of extra-cerebral infection after subarachnoid hemorrhage: a single center cohort study.

Oct 01, 2020

Subarachnoid hemorrhage (SAH) is associated with high morbidity. Among all complications, infections, in particular if hospital-acquired, could represent an important cause of death in SAH patients. T...

Positive Beliefs the Likelihood of Successful Community Discharge from Skilled Nursing Facilities.

Oct 01, 2020

Examine the association of patient and direct-care staff beliefs about patients' capability to increase independence with activities of daily living (ADLs) and the probability of successful discharge ...

Is The Glymphatic System the Missing Link Between Sleep Impairments and Neurological Disorders? Examining the Implications and Uncertainties.

Oct 01, 2020

Until recently, both the purpose of the biological need for sleep and the mechanism by which the central nervous system eliminated metabolic waste products were unknown. The glymphatic system is the r...

Global mean diffusivity: a radiomarker discriminating good outcome long term after traumatic brain injury.

Oct 01, 2020

Traumatic brain injury (TBI) is a chronic pathology responsible for cognitive disorders impacting outcome. Global clinical outcome several years after TBI may be associated with anatomical sequelae. A...

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