Nov 26, 2020

Sepsis is an intractable clinical syndrome characterised by organ dysfunction when the body over-responds to an infection. Sepsis has a high fatality rate and lacks effective treatment. Family with se...

Nov 26, 2020

Traumatic brain injury (TBI) and hemorrhage remain the leading causes of death after trauma. We have previously shown that a dose of Valproic Acid (VPA) at (150 mg/kg) can decrease brain lesion size &...

Nov 26, 2020

Acquired brain injury affects many brain areas and causes a range of dysfunctions including vision-related issues. These issues can have negative impacts on rehabilitation progress and activities of d...

Nov 26, 2020

Review the literature on predictors of participation and quality of life in children and young people who sustained a traumatic brain injury (TBI), spinal cord injury (SCI), and/or multi-trauma in a m...

Nov 26, 2020

Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus-2. The clinical presentation of this virus mainly manifests in the respiratory system but may also lead t...

Nov 26, 2020

African-American and Hispanic postmenopausal women have the highest risk for heart failure (HF) compared to other races, but HF prevalence is lower than expected in some national cohorts. It is unknow...

Nov 26, 2020

The NOD-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome activation-mediated pyroptosis pathway has been linked to myocardial ischemia-reperfusion (MI/R) injury. This study explore...

Nov 26, 2020

Phosphodiesterase-5A inhibitors (PDE5i) are sometimes used in patients with advanced HFrEF prior to heart transplant or LVAD to reduce RV afterload and mitigate the risk of right HF. Conflicting evide...

Nov 26, 2020

 Previous studies showed inconsistent results regarding associations between inflammatory bowel disease (IBD) and risk of ischemic heart disease (IHD) and diabetes. The present study aimed to make a...

Nov 23, 2020

Stroke leads to significant neuronal death and long-term neurological disability due to synergistic pathogenic mechanisms. Stroke induces a change in eating habits and in many cases, leads to undernut...

Nov 23, 2020

Cannabinoids have been shown to protect the retina from ischemic/excitotoxic insults. The aim of the present study was to investigate the neuroprotective and anti-inflammatory properties of the synthe...

Nov 23, 2020

The prevalence of obesity is increasing. The association with knee osteoarthritis is well documented, resulting in the population requesting total knee arthroplasty (TKA) for invalidating symptoms to ...

Nov 23, 2020

The outbreak of coronavirus disease 2019 (COVID-19) with the origin of the spread assumed to be located in Wuhan, China, began in December 2019, and is continuing until now. With the COVID-19 pandemic...

Nov 23, 2020

The long-term effects of ambient PM and chemical constituents on childhood pneumonia were still unknown. A cross-sectional study was conducted in 30,315 children in the China Children, Homes, Health (...

Nov 23, 2020

The risk and burden of cardiovascular disease (CVD) are higher in homeless than in housed individuals but population-based analyses are lacking. The aim of this study was to investigate prevalence, in...

Nov 23, 2020

Early-onset sepsis (EOS) is a potentially life-threatening complication of birth. Clinical symptoms are often unspecific and biomarkers have low predictive values for EOS. Therefore, clinical suspicio...

Nov 23, 2020

Bacterial infection triggers a cytokine storm that needs to be resolved to maintain the host's wellbeing. Here, we report that ablation of mA methyltransferase subunit METTL14 in myeloid cells exacerb...

Nov 23, 2020

The primary lesion arising from the initial insult after traumatic brain injury (TBI) triggers a cascade of secondary tissue damage, which may also progress to connected brain areas in the chronic pha...

Nov 23, 2020

Despite its many benefits, bicycling carries the risk of accidents. Although numerous studies have reported the effect of helmet use on traumatic brain injury, it remains unclear if, and to what exten...

Nov 23, 2020

Impairments in gait and balance function are typical after concussion. There is evidence that these neuromuscular deficits persist past the typical time of symptom resolution. The ability to quantify ...