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Critical Care General

Can carotid artery calcifications on dental radiographs predict adverse vascular events? A systematic review.

Nov 30, 2020

To investigate the predictive value of carotid artery calcifications (CACs) seen on dental imaging for future adverse events related to cerebrovascular and cardiovascular diseases.Electronic databases...

Optimal Empiric Treatment for Infections in Short-Stay ICU Patients During Continuous Renal Replacement Therapy: Results from a Population Pharmacokinetic/Pharmacodynamic Analysis.

Nov 30, 2020

There is a paucity of published data to evaluate the efficacy and safety of imipenem (IPM) and piperacillin-tazobactam (PT) dosing regimens in the treatment of septic patients acquiring continuous ren...

Primarily treated patients versus referred patients in the treatment of native septic arthritis of digits: a retrospective comparative study.

Nov 30, 2020

Septic arthritis of digits needs urgent treatment. When treatments delayed or insufficient, patients may be referred to the upper-level hospital due to uncontrolled infection. We reviewed the treatmen...

Gene expression signatures identify paediatric patients with multiple organ dysfunction who require advanced life support in the intensive care unit.

Nov 30, 2020

Multiple organ dysfunction syndrome (MODS) occurs in the setting of a variety of pathologies including infection and trauma. Some patients decompensate and require Veno-Arterial extra corporeal membra...

Position Paper on Post-Traumatic Headache: The Relationship Between Head Trauma, Stress Disorder, and Migraine.

Nov 30, 2020

Traumatic brain injury (mTBI) is a major public health concern, with mild TBI (mTBI) constituting the vast majority of the injuries. Post-traumatic headache (PTH) is one of the most frequent symptoms ...

Effects of Fibrinogen Synthesis Inhibition on Vascular Cognitive Impairment during Traumatic Brain Injury in Mice.

Nov 30, 2020

Traumatic brain injury (TBI) is associated with increased blood content of fibrinogen (Fg), called hyperfibrinogenemia (HFg), which results in enhanced cerebrovascular permeability and leads to short-...

Ion Channels and Transporters in Microglial Function in Physiology and Brain Diseases.

Nov 30, 2020

Microglial cells interact with all components of the central nervous system (CNS) and are increasingly recognized to play essential roles during brain development, homeostasis and disease pathologies....

I want to go home. Should we abandon open surgery for treatment of rectal prolapse? Consideration of discharge destination following surgery for rectal prolapse.

Nov 30, 2020

Despite the financial and value-based implications associated with higher levels of care at discharge, few studies have evaluated modifiable treatment factors that may optimize post-acute care. The ai...

The impact of psychoeducational interventions on the outcomes of caregivers of patients with heart failure: A systematic review and meta-analysis.

Nov 30, 2020

Heart failure is a global health care problem that causes a significant economic burden. Despite medical advancements, it's prognosis remains poor as many patients with heart failure experience sympto...

Are early measured resting-state EEG parameters predictive for upper limb motor impairment six months poststroke?

Nov 30, 2020

Investigate whether resting-state EEG parameters recorded early poststroke can predict upper extremity motor impairment reflected by the Fugl-Meyer motor score (FM-UE) after six months, and whether th...

Predictive model of Ischemic optic neuropathy in spinal fusion surgery using a longitudinal medical claims database.

Nov 30, 2020

Perioperative ischemic optic neuropathy (ION) is a devastating complication of spinal fusion surgery.To develop predictive models of this blinding condition using longitudinal medical administrative c...

Treatment Approaches and Outcomes for Acute Anterior Circulation Stroke Patients with Tandem Lesions.

Nov 30, 2020

Endovascular thrombectomy (EVT) has revolutionized stroke care for large vessel occlusions (LVOs). However, over half treated remain functionally disabled or die. Patients with tandem lesions, or seve...

An Unusual Case of Iron-Deficiency Anemia: The Culprit Hides in the Aorta.

Nov 26, 2020

In a 72-year-old patient with anemia (Hb 7 g/dl), duodenoscopy exhibited an area of polypous irregular-looking mucosa. Histology revealed duodenal infiltration by epithelioid tumor cells, immunhisto...

Effects of S100B neutralization on the long-term cognitive impairment and neuroinflammatory response in an animal model of sepsis.

Nov 26, 2020

The nervous system is one of the first systems to be affected during sepsis. Sepsis not only has a high risk of mortality, but could also lead to cerebral dysfunction and cognitive impairment in long-...

Short Bowel Syndrome: Epidemiology, Hospitalization trends, In-hospital Mortality, and Healthcare utilization.

Nov 26, 2020

Short Bowel Syndrome (SBS) is a common cause of chronic intestinal failure and is associated with increased morbidity, mortality, poor quality of life, and an increased burden on health care costs.We ...

Comparative lung distribution of radiolabelled tobramycin between nebulized and intravenous administration in a mechanically ventilated ovine model, an observational study.

Nov 26, 2020

Ventilator associated pneumonia occurs commonly and nebulized antibiotics are being used for its treatment. Although adequate pulmonary biodistribution is important for antibiotic effect, there is a l...

Risk factors associated with the progression of COVID-19 in elderly diabetes patients.

Nov 26, 2020

To describe the clinical characteristics and risk factors associated with the progression of COVID-19 in elderly diabetes patients.This was a retrospective cohort study, including elderly COVID-19 pat...

The impact of a stewardship programme on antibiotic administration in community-acquired pneumonia: results from an observational before-after study.

Nov 26, 2020

A majority of patients with community-acquired pneumonia (CAP) receive antibiotics. According to the evidence, 5-7 days of treatment should be sufficient for most patients. Many, however, are treated ...

Emerging challenges in the evaluation of fever in cancer patients at risk of febrile neutropenia in the era of COVID-19: a MASCC position paper.

Nov 26, 2020

Patients with cancer are at higher risk of more severe COVID-19 infection and have more associated complications. The position paper describes the management of cancer patients, especially those recei...

Leukopenia and Neutropenia at Birth and Sepsis in Preterm Neonates of <32 Weeks' Gestation.

Nov 26, 2020

 This study aimed to evaluate associations between leukopenia or neutropenia at birth and risk of sepsis in very preterm neonates. We conducted a retrospective unmatched cohort study of neonates o...

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