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Critical Care General

Estradiol resolves pneumonia via ER-β regulatory T cells.

Dec 10, 2020

Current treatments for pneumonia (PNA) are focused on the pathogens. Mortality from PNA-induced acute lung injury (PNA-ALI) remains high, underscoring the need for additional therapeutic targets. Clin...

Clinicopathologic Features of Tissue Granulomas in Transplant Recipients: A Single Center Study in a Nontuberculosis Endemic Region.

Dec 10, 2020

There is a paucity of literature about tissue granulomas in transplant patients.To characterize the clinicopathologic features of granulomas in this population and develop a clinically judicious appro...

Trends in Cardiovascular Complications and Mortality among Patients with Diabetes in South Korea.

Dec 10, 2020

We investigated the cardiovascular complications and mortality rates of patients with diabetes in South Korea. The rates of hospitalization due to cardiovascular complications and mortality were analy...

Effect Of Pre-Operative Β-Blocker Therapy After Cabg Surgery: Long-Term Survival And Postoperative Complications.

Dec 10, 2020

Introduction Perioperative medication in cardiac surgery recommends β-blockers' use but it is not clear if its prescription should be started before or after cardiac surgery. Objectives To determine ...

Burden of carbapenem non-susceptible infections in high-risk patients: systematic literature review and meta-analysis.

Dec 10, 2020

Owing to their resistance to an important class of antibiotics, the prevention and treatment of carbapenem-resistant (CR)/non-susceptible Gram-negative (GN) infections has become an important public h...

Menstrual blood-derived stromal cells modulate functional properties of mouse and human macrophages.

Dec 10, 2020

Menstrual blood-derived stromal cells (MenSCs) are emerging as a strong candidate for cell-based therapies due to their immunomodulatory properties. However, their direct impact on innate immune popul...

Patient-specific cruciate-retaining total knee replacement with individualized implants and instruments (iTotal™ CR G2).

Dec 10, 2020

Treatment of tricompartimental osteoarthritis (OA) using customized instruments and implants for cruciate-retaining total knee arthroplasty. Use of patient-specific instruments and implants (ConforMIS...

Biomechanical analysis of skull trauma and opportunity in neuroradiology interpretation to explain the post-concussion syndrome: literature review and case studies presentation.

Dec 10, 2020

Traumatic head injuries are one of the leading causes of emergency worldwide due to their frequency and associated morbidity. The circumstances of their onset are often sports activities or road accid...

Links between thrombosis and inflammation in traumatic brain injury.

Dec 10, 2020

Traumatic brain injury (TBI) continues to be a major healthcare problem and there is much to be explored regarding the secondary pathobiology to identify early predictive markers and new therapeutic t...

Role for histone deacetylation in traumatic brain injury-induced deficits in neuropeptide Y in arcuate nucleus: Possible implications in feeding behaviour.

Dec 10, 2020

Repeated traumatic events result in long-lasting neuropsychiatric ailments, including neuroendocrine imbalances. Neuropeptide Y (NPY) in the arcuate nucleus (Arc) is an important orexigenic peptide. H...

Meta-Analysis of the Usefulness of Catheter Ablation of Atrial Fibrillation in Patients with Heart Failure with Preserved Ejection Fraction.

Dec 10, 2020

Catheter ablation improves clinical outcomes in atrial fibrillation (AF) patients with heart failure (HF) with reduced ejection fraction (HFrEF). However, the role of catheter ablation in HF with a pr...

Tracheostomy in the pediatric trisomy 21 population.

Dec 10, 2020

Tracheostomy in children is often performed to alleviate airway obstruction (AO) or to facilitate long-term ventilator support due to respiratory failure of various etiologies, such as heart failure, ...

The risk of cardiac events in patients receiving immune checkpoint inhibitors: a nationwide Danish study.

Dec 10, 2020

The study aimed to estimate the risk of cardiac events in immune checkpoint inhibitor (ICI)-treated patients with lung cancer or malignant melanoma.The study included consecutive patients with lung ca...

Characterizing spatiotemporal progression and prediction of infarct lesion volumes in experimental acute ischemia using quantitative perfusion and diffusion imaging.

Dec 10, 2020

This study was conducted to explore the diagnostic value of arterial spin labeling (ASL) combined with diffusion weighted imaging (DWI) in characterizing the spatiotemporal progression of infarct lesi...

Atherosclerosis is associated with poorer outcome in non-occlusive mesenteric ischemia.

Dec 10, 2020

To evaluate whether abdominal atherosclerosis was associated with poorer outcome in a single-centre cohort of patients suffering from nonocclusive mesenteric ischemia (NOMI).From January 2009 to Decem...

Red and White Thrombus Characteristics in Patients Undergoing Carotid Endarterectomy.

Dec 07, 2020

The study aimed to compare the characteristics of red and white thrombi in patients undergoing carotid endarterectomy.The study was conducted in 81 patients with ischemic stroke who underwent carotid ...

Synovial fluid presepsin as a novel biomarker for the rapid differential diagnosis of native joint septic arthritis from crystal arthritis.

Dec 07, 2020

To investigate whether presepsin can be used as a novel biomarker to differentiate between native joint septic arthritis (NJSA) and crystal arthritis (CA).This study included 75 patients diagnosed wit...

The Use of Real-Time 3D Intraoperative Ultrasound "Angiography" in Localization and Occlusion Control of a Ruptured Mycotic Aneurysm: A Case Report.

Dec 07, 2020

 Infectious (mycotic) aneurysms are rare with high mortality and are most commonly found at the distal branches of the middle cerebral artery (MCA). Because aneurysms of the distal MCA are located d...

Low-dose Whole-lung Irradiation for COVID-19 Pneumonia: Final Results of a Pilot Study.

Dec 07, 2020

Radiotherapy (RT) -commonly employed in cancer management- has been considered as one of the potential treatments for COVID-19 pneumonia. Here, we present the results of the pilot trial evaluating low...

Myeloid arginase-1 controls excessive inflammation and modulates T cell responses in Pseudomonas aeruginosa pneumonia.

Dec 07, 2020

Regulatory properties of macrophages associated with alternative activation serve to limit the exaggerated inflammatory response during pneumonia caused by Pseudomonas aeruginosa infection. Arginase-1...

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