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Hybrid closed-loop therapy improves glycemic control for children with Type 1 Diabetes

1. In very young children with type 1 diabetes, a hybrid closed-loop therapy provided significantly improved glycemic children. 2. The hybrid closed-loop therapy did not significantly increase the time spent in hypoglycemia in very young children with type 1 diabetes. Evidence Rating Level: 1 (Excellent) Study Rundown: In very young children, managing Type 1 Diabetes […]

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Intracranial efficacy of alectinib in ALK-positive NSCLC patients with CNS metastases

1. Treatment with alectinib reduced CNS lesion sizes and significantly improved symptoms, ECOG performance scores and requirements for mannitol and corticosteroids in patients with metastases from non-small cell lung cancer. Evidence Level Rating: 2 (Good) Central nervous system metastases are highly prevalent in patients with ALK gene mutations driving advanced non-small cell lung cancer despite […]

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